Dear speakers, poster presenters, and participants,
We, including all our coworkers, wish to thank you for your great contributions which caused this conference to become a big success.
As we have got tons of pics, we will compile a selection for Picasa and then send the access address to all of you.
Thanks again and best regards,
Michael Fromm & J?g Schulzke
 
Posters and winners of the poster awards

Program Upate 27.09.11

duration = talk time+discussion time (min), resulting in 15, 20, and 25 min slots. 

Thursday, September 22

 time

duration

 

 

14:00

5

Michael Fromm,
J?g Schulzke

Opening

 

10

Annette Gr?ers-Kieslich,
Dean of Charit?/span>

Welcome address

14:15

 

Session A
Chairs: Jerrold Turner, Dorothee G?zel

Molecular structure of the tight junction

 

20+5

Alan Yu (Kansas City, KS)

Structure-function studies of the claudin ion pore

 

20+5

Ingolf Blasig (FMP Berlin, Germany)

Heterologous interactions between TJ proteins

 

20+5

Mikio Furuse (Kobe, Japan)

Tricellular tight junction formation

 

16+4

J?g Piontek (FMP Berlin, Germany)

Protein interactions and morphometric analysis of claudins

 

16+4

Gerd Krause (FMP Berlin, Germany)

Structural bioinformatic studies on protein interactions of classic claudins

 

30

Coffee break

 

 

16+4

Otmar Huber (Jena, Germany)

CK2-dependent phosphorylation of occludin

 

12+3

Christopher Weber (Chicago, IL)

Submicron dynamics of tight junction structure and function

 

16+4

Werner Franke (Heidelberg, Germany)

A new category of structures: Tight junction proteins out of tight junctions

 

20+5

Asma Nusrat (Atlanta, GA)

Unraveling relationships between intercellular junction proteins and epithelial homeostasis

 

12+3

Johan S?erholm (Linkoeping, Sweden)

Bacterial-epithelial interaction in the follicle-associated epithelium of Crohn's disease

18:30

open

Get together Dinner Buffet
@Harnack House

 

 

Friday, September 23

9:00

 

Session B
Chairs: Martin Zeitz, Ursula Seidler

Inflammation and gastrointestinal function

 

16+4

Alessio Fasano (Baltimore, MD)

Zonulin, tight junctions regulation, and autoimmune diseases: The celiac disease and type 1 diabetes paradigms

 

12+3

Hans-J?g Epple (Berlin, Germany)

Intestinal mucosal barrier function in HIV infection

 

20+5

Gail Hecht (Chicago, IL)

Control of intestinal epithelial tight junctions by enteropathogenic E. coli

 

12+3

Michael Schumann (Berlin, Germany) Defective tight junctions and altered cell polarity in celiac disease

 

20+5

Marshall Montrose (Cincinnati, OH)

Interventional imaging of the gastric barrier in vivo

 

30

Coffee break

 

 

20+5

Sachiko Tsukita (Osaka, Japan)

Knockout mouse studies of barrier-type and ion-leaky-type claudins on inflammation and nutrient-absorption

 

16+4

Dietmar Vestweber (M?ster, Germany)

Regulation of endothelial cell contacts in leukocyte extravasation

 

16+4

Jon Meddings (Edmonton, Canada)

Increased permeability in relatives - what does it mean?

 

12+3

Le Shen (Chicago, IL)

Tight junction determinants of TNF-induced epithelial dysfunction

 

20+5

Jerrold Turner (Chicago, IL)

From tight junction molecular interactions to barrier restorative therapeutic approaches

13:00

90

Poster-Lunch Buffet

 

 

14:30

 

Session C
Chairs: James Anderson, Rudolf Tauber

Regulation of the tight junction and barrier function

 

16+4

Alastair Watson (Norwich, UK) Cell shedding and epithelial barrier function

 

12+3

Kai Schmidt-Ott (MDC Berlin, Germany)

Transcriptional control of apical junctional complex composition in epithelia

 

16+4

Alan Fanning (Chapel Hill, NC)

Novel Insights into the role of ZO-1 and ZO-2 in the regulation of epithelial permeability and cytoskeletal dynamics at cell-cell junctions

 

16+4

Sandra Citi (Geneva, Switzerland)

Cingulin, paracingulin, and PLEKHA7: Signaling modules at epithelial tight and adherens junctions

 

16+4

Christina van Itallie (Bethesda, MD)

Assembly and modification of claudins

 

30

Coffee break

 

 

16+4

Klaus Beyenbach (Ithaca, NY)

Signaling to the paracellular pathway: A proteomic analysis

 

20+5

Takashi Kojima (Sapporo, Japan)

Regulation of tight junctions in normal human pancreatic duct epithelial cells and cancer cells

 

16+4

Charles Parkos (Atlanta, GA)

The many contributions of junctional proteins to mucosal pathobiology: Lessons learned from JAM proteins

 

16+4

Declan McCole (San Diego, CA)

Regulation of epithelial barrier function by the IBD candidate gene, PTPN2

 

12+3

Michael Scharl (Z?ich, Switzerland)

The role for PTPN2 in maintaining intestinal barrier function by regulating autophagy and apoptosis

19:00

90

Dinner @ Harnack house

 

20:30

open

"The Tight Junctions"

Classic rock

 

Saturday, September 24

9:00

 

Session D
Chairs: Daniel Teitelbaum, J?gen Stein

Epithelial transport, barrier repair, food components

 

12+3

Maren Amasheh (Berlin, Germany)

Intestinal barrier protection by plant secondary metabolites

 

12+3

J?g Aschenbach (FU Berlin, Germany)

Microbial butyrate and its effect on epithelia of the gastrointestinal tract

 

16+4

Daniel Teitelbaum (Ann Arbor, MI)

Total parenteral nutrition and loss of intestinal barrier function: How what you don't eat can hurt you

 

12+3

Markus Bleich (Kiel, Germany)

Calcium regulation of tight junction permeability

 

16+4

Masuo Kondoh (Osaka, Japan)

Development of claudin binders using a baculoviral displaying system

 

30

Coffee break

 

 

16+4

James Anderson (Bethesda, MD)

Characterizing epithelial oxalate transport: A possible link between IBD and oxalate nephrolithiasis

 

16+4

Salah Amasheh (Berlin, Germany)

Effects of absorption enhancers in intestinal epithelial cell models

 

12+3

Stefania Vetrano (Milano, Italy)

Unexpected role of the anti-coagulative protein C in controlling epithelial barrier integrity and intestinal inflammation

 

12+3

Salim Seyfried (MDC Berlin, Germany)

Elucidating the developmental roles of claudin-5 using the zebrafish embryo

 

20+5

Johanna Brandner (Hamburg, Germany)

Barriers and more: Function of tight junction proteins in the skin

12:30

90

Poster-Lunch Buffet

 

 

14:00

 

Session E
Chairs: Werner Franke, Hans-Joachim Galla

Tight junctions in lung, renal, endothelial, and nerval tissues

 

12+3

James A. Frank (UCSF, CA)

Regulation of epithelial barrier function and repair in the lung by claudins

 

20+5

Michael Koval (Atlanta, GA)

Transport and assembly of claudins: Regulation and misregulation in alcoholic lung disease

 

16+4

Martin Konrad (M?ster, Germany)

Tight junction defects in human renal diseases

 

12+3

Susanne Krug (Berlin, Germany)

Claudin-17 forms anion-selective channels and is present in proximal kidney tubules

 

16+4

Dorothee G?zel (Berlin, Germany)

Lessons from impedance

 

30

Coffee break

 

 

16+4

Jianghui Hou (St. Louis, MO)

The role of claudin in renal handling of magnesium and calcium

 

16+4

Heike Rittner (W?zburg, Germany)

Tight junction proteins in the perineurium for regional pain control

 

20+5

Lorenza Gonzalez-Mariscal (Mexico City, Mex)

ZO-2 protects against podocyte disfunction in a model of nephropathy induced by ADR in mice

10

Lorenza Gonzalez-Mariscal (Mexico City, Mex) Announcement of the conference "Molecular Structure and Function of Tight Junctions" in Merida, Mexico, Oct. 2012

 

10

J?g Schulzke

Closing remarks

18:15

 

Departure for Dinner @ Schloss Glienicke

 

   

Posters 

A poster jury, consisting of Asma Nusrat, Alastair Watson, and Alan Yu, has elected three presenters, who will be invited to submit regular articles for a dedicated Ann. NY Acad. Sci. volume.

Winners of the poster awards (in alphabetic order):

Christian Barmeyer, Irene Erko, Anja Fromm, Christian Bojarski, Jan F. Richter, Christoph Loddenkemper, Martin Zeitz, Michael Fromm, J?g-Dieter Schulzke. Diarrhea in lymphocytic colitis is characterized by malabsorption and a barrier defect. Department of Gastroenterology, Infectious Diseases, and Rheumatology, Charit? Campus Benjamin Franklin, Berlin, Germany

Victor Castro, Christian Bellman, Susanne M. Krug, Michael Fromm, Ingolf E. Blasig. On the functional relevance of the C-terminal domain of occludin. Leibniz-Institute of Molecular Pharmacology (FMP), Berlin, Germany

Caroline Weight, Simon Carding. The protozoan parasite Toxoplasma gondii targets epithelial tight junctions and occludin to invade the host. Institute of Food Research, Norwich, UK

 

1

Christian Barmeyer (Charit? Berlin)

Diarrhea in lymphocytic colitis is characterized by malabsorption and a barrier defect

2

Roland B?ker (Charit? Berlin)

Tight junction changes in intestinal epithelial cells by Campylobacter jejuni and non-jejuni Campylobacter species

3

Victor Castro (FMP, Berlin)      

On the functional relevance of the C-terminal domain of occludin

4

Jimmi Cording (FMP, Berlin)

Principles of the molecular organization of cerebral tight junctions

5

Dagmar Hackel (W?zburg, Germany)

Antinociception of perineurally applied drugs via modulation of tight junction proteins in the perineurium

6

Nina Hering (Charit? Berlin)

Up-regulation of claudin-14 by probiotic E. coli Nissle enhances barrier function in human colon cell line HT-29/B6

 7

Marina Juric (Hannover, Germany) Enhanced luminal alkalization and increased epithelial permeability in TNF-α overexpressing murine proximal colon

8

Alexander Markov (St. Petersburg, Russia)

Tight junctions of murine lactating mammary epithelium

9

Susanne Milatz (Charit? Berlin)

Endothelial tight junction proteins are regualted by shear stress and hypoxia

10

Yusuke Ono (Sapporo, Japan)

Significant expression of tricellulin in the nuclei is associated with cell proliferation in human pancreatic cancer cells

11

Svenja Pl?er (FU, Berlin)

Barrier stabilization in HT-29/B6-GR/MR cells via HNF-4alpha-dependent down-regulation of claudin-2 by sodium butyrate

12

Arina Riabinska (Charit? Berlin)

Influence of pigment epithelium-derived factor on blood brain barrier in normal and ischemic brain

13

Jan Richter (Charit? Berlin)

Cholera toxin subunit B increases bystander cargo uptake and transcytosis in intestinal epithelial cells

14

Rita Rosenthal (Charit? Berlin)

Water permeability of tight junction proteins

17

Christian Staat (FMP, Berlin)

Structure and action of claudin peptidomimetics

16

Atsushi Tamura (Osaka, Japan)

Loss of claudin-2 and -15 causes Na+ deficiency and malabsorption in mouse small intestine

17

Hanno Troeger (Charit? Berlin)

Epithelial barrier dysfunction in human intestinal graft-versus-host disease

18

Christian Tscheik (FMP, Berlin)

The effect of sodium caprate on claudin-5/claudin-5 interactions

19

Luzia Valentini (Charit? Berlin)

Bridging low grade inflammation with intestinal barrier function and gut microbiota in elderly humans

20

Anna Veshnyakova (FMP, Berlin)

Molecular determinants for sealing and/or pore formation: Chimera studies between claudin-1 and claudin-2

21

Juliane Walter, Reiner Haseloff (FMP, Berlin)

Proteomic approaches for identification of proteins bound to PDZ domains of Zonula occludens-1

22

Caroline Weight (Norwich, UK)

The protozoan parasite Toxoplasma gondii targets epithelial tight junctions and occludin to invade the host

23

Yuji Yamazaki (Osaka, Japan)

Regulation of claudin species-specific polymerization for forming epithelial tight junctions

  
DFG Research Unit FOR 721: www.charite.de/klinphysio/for721/index_e.htm
Institute of Clinical Physiology: www.charite.de/klinphysio/index_e.htm

Harnack House of the Max Planck Society: www.harnackhaus-berlin.mpg.de/eng-index.htm      Virtual tour