2020  (updated 12.04.20)

• Barmeyer C, Erko I, Fromm A, Bojarski C, Loddenkemper C, Dames P, Kerick M, Siegmund B, Fromm M, Schulzke JD (2016) ENaC dysregulation through activation of MEK1/2 contributes to impaired Na⁺ absorption in lymphocytic colitis. Inflamm. Bowel Dis. 22(3): 539-547 (IF 4.5) [PubMed] [WebPage] [PDF]

• Conrad MP*, Piontek J* (*shared first authorship), Günzel D, Fromm M, Krug SM (2016) Molecular basis of claudin-17 anion selectivity. Cell. Mol. Life Sci. 73(1): 185-200 (IF 5.8) [PubMed] [WebPage] [PDF] [Supplement]

• Demehri FR*, Krug SM* (*shared first authorship), Feng Y, Lee IM, Schulzke JD, Teitelbaum DH (2016) Tight junction ultrastructure alterations in a mouse model of enteral nutrient deprivation. Dig. Dis. Sci. 61(6): 1524-1533 (IF 2.9)  [PubMed] [WebPage] [PDF]

• Hering NA, Fromm A, Kikhney J, Lee IM, Moter A, Schulzke JD, Bücker R (2016) Yersinia enterocolitica affects intestinal barrier function in the colon. J. Infect. Dis. 213(7): 1157-1162 (IF 6.3) [PubMed] [WebPage] [PDF]

• Liao Z, Yang Z, Piontek A, Eichner M, Krause G, Chen B, Li L, Piontek J, Zhang J (2016) Specific binding of a mutated fragment of Clostridium perfringens enterotoxin to endothelial claudin-5 and its modulation of cerebral vascular permeability. Neuroscience 327: 53-63 (IF 3.3) [PubMed] [WebPage] [PDF]

• Luettig J, Rosenthal R, Lee IM, Krug SM, Schulzke JD (2016) The ginger component 6-shogaol prevents TNFα-induced barrier loss via inhibition of PI3K/Akt and NF-kB sigaling. Mol. Nutr. Food Res. 60(12): 2576-2586 (IF 4.3) [PubMed] [WebPage] [PDF]

• Mudnakudu Nagaraju KK, Babina M, Weise C, Kühl A, Schulzke JD, Worm M (2016) Bortezomib treatment diminishes hazelnut-induced intestinal anaphylaxis in mice. Eur. J. Immunol. 46(7): 1727-1736 (IF 4.2) [PubMed] [WebPage] [PDF]

• Preiß JC, Barmeyer C, Bürgel N, Daum S, Epple HJ, Günther U, Maul J, Siegmund B, Schumann M, Tröger H, Stroux A, Adler A, Veltzke-Schlieker W, Jürgensen C, Wentrup R, Wiedenmann B, Binkau J, Hartmann D, Nötzel E, Domagk D, Wacke W, Wahnschaffe U, Bojarski C (2016) EndoClot polysaccharide hemostatic system in nonvariceal gastrointestinal bleeding: results of a prospective multicenter observational pilot study. J. Clin. Gastroenterol. 50(10): e95-e100 (IF 3.3) [PubMed] [WebPage] [PDF]

• Richter JF, Schmauder R, Krug SM, Gebert A, Schumann M (2016) A novel method for imaging sites of paracellular passage of macromolecules in epithelial sheets. J. Contr. Release 229: 70-79 (IF 7.8) [PubMed] [WebPage] [PDF] [Supplement] [Movie S1] [Movie S2]

• Yang S*, Krug SM* (*shared first authorship), Heitmann J, Hu L, Reinhold AK, Sauer S, Bosten J, Sommer C, Fromm M, Brack A*, Rittner HL* (*shared last authorship) (2016) Analgesic drug delivery via recombinant tissue plasminogen activator and mRNA-183-triggered opening of the blood-nerve barrier. Biomaterials 82: 20-33 (IF 8.4) [PubMed] [WebPage] [PDF] [Supplement]

2011

2010

• Amasheh M, Fromm A, Krug SM, Amasheh S, Andres S, Zeitz M, Fromm M, Schulzke JD (2010) TNFa-induced and berberine-antagonized tight junction barrier impairment via tyrosine kinase, pAkt, and NFkB signaling. J. Cell Sci. 123(23): 4145-4155 [PubMed] [WebPage] [PDF] [Supplements]

• Becker S*, Wandel E* (*shared first authorship), Wobus M, Schneider R, Amasheh S, Sittig D, Kerner C, Naumann R, Hamann J, Aust G (2010) Overexpression of CD97 in intestinal epithelial cells of transgenic mice attenuates colitis by strengthening adherens junctions. Plos One 5(1): e8507 (print 1-11) [PubMed] [WebPage] [PDF]

• Epple HJ, Allers K, Tröger H, Kühl A, Erben U, Fromm M, Zeitz M, Loddenkemper C*, Schulzke JD*, Schneider T* (*shared last authorship) (2010) Acute HIV infection induces mucosal infiltration with CD4+ and CD8+ T cells, epithelial apoptosis, and a mucosal barrier defect. Gastroenterology 139(4): 1289-1300 [PubMed] [WebPage] [PDF] [Supplement PDF]

• Hillenbrand B, Günzel D, Richter JF, Höhne, Schreier E, Schulzke JD, Mankertz J (2010) Norovirus non-structural protein p20 leads to impaired restitution of epithelial defects by inhibition of actin cytoskeleton remodelling. Scand. J. Gastroent. 45(11): 1307-1319 [PubMed] [WebPage] [PDF]

• Kirschner N, Houdek P, Fromm M, Moll I, Brandner JM (2010) Tight junctions form a barrier in human epidermis. Eur. J. Cell Biol. 89(11): 839-842 [PubMed] [WebPage] [PDF]

• Markov AG*, Veshnyakova A* (*shared first authorship), Fromm M, Amasheh M, Amasheh S (2010) Segmental expression of claudin proteins correlates with tight junction barrier properties in rat intestine. J. Comp. Physiol. B 180(4): 591-598 [PubMed] [WebPage] [PDF]

• Milatz S, Krug SM, Rosenthal R, Günzel D, Müller D, Schulzke JD, Amasheh S*, Fromm M* (*shared last authorship) (2010) Claudin-3 acts as a sealing component of the tight junction for ions of either charge and uncharged solutes. Biochim. Biophys. Acta Biomembr. 1798: 2048-2057 [PubMed] [WebPage] [PDF]

• Schmid T, Günzel D, Bogdan M (2010) Using an artificial neural network to determine electrical properties of epithelia. In: Diamantaras K, Duch W, Iliadis LS Eds., ICANN 2010, Part I, Lect. Notes Comput. Sci. 6352: 211-216 (DOI: 10.1007/978-3-642-15819-3_28) [Abstract] [PDF]

• Preston P, Wartosh L, Günzel D, Fromm M, Kongsuphol P, Ousingsawat J, Kunzelmann K, Barhanin J, Warth R, Jentsch TJ (2010) Disruption of the K⁺-channel β-subunit KCNE3 reveals an important role in colonic and tracheal Cl^- transport. J. Biol. Chem. 285(10): 7165-7175 [PubMed] [PDF] [Supplement]

• Rosenthal R, Milatz S, Krug SM, Oelrich B, Schulzke JD, Amasheh S, Günzel D, Fromm M (2010) Claudin-2, a component of the tight junction, forms a paracellular water channel. J. Cell Sci. 123(11): 1913-1921 [PubMed] [WebPage] [PDF] [Supplement]

• Schulzke JD*, Pfaffenbach S* (*shared first authorship), Fromm A, Epple HJ, Troeger H*, Fromm M* (*shared last authorship) (2010) PGI₂ sensory input into the ENS during distension-induced colonic chloride secretion in rat colon. Acta Physiol. 199(3): 305-316 [PubMed] [WebPage] [PDF]

• Westphal JK, Dörfel MJ, Krug SM, Cording JD, Piontek J, Blasig IE, Tauber R, Fromm M, Huber O (2010) Tricellulin forms homomeric and heteromeric tight junctional complexes. Cell. Mol. Life Sci. 67(12): 2057-2068 [PubMed] [WebPage] [Supplement WebPage] [PDF] [Suppl. Fig. 1] [Suppl. Fig. 2]

• Will C, Breiderhoff T, Thumfart J, Stuiver M, Kopplin K, Sommer K, Günzel D, Querfeld U, Meij IC, Shan Q, Bleich M, Willnow TE, Müller D (2010) Targeted deletion of murine Cldn16 identifies extra- and intrarenal compensatory mechanisms of Ca²⁺ and Mg²⁺ wasting. Am. J. Physiol. Renal Physiol. 298: F1152-F1161 [PubMed] [WebPage] [PDF]

  • Reviews / Textbook chapters

• Bücker R, Schumann M, Amasheh S, Schulzke JD (2010) Claudins in intestinal function and disease. Curr. Top. Membr. 65: 195-227 [Directory] [WebPage] [PDF] (Review / book chapter)  

• Fromm M (2010) Chapter 3 "Transport in Membranen und Epithelien", In: Physiologie des Menschen mit Pathophysiologie. Schmidt RF, Lang F, Heckmann M (eds.), 31. edn., Springer Medizin, Heidelberg. ISBN 978-3-642-01650-9, p 36-48 and 895-897, review booklet 3-4. [Publisher's ad] (Textbook of Physiology)

• Günzel D, Krug SM, Rosenthal R, Fromm M (2010) Biophysical methods to study tight junction permeability. Curr. Top. Membr. 65: 39-78 [Directory] [WebPage] [PDF] (Review / book chapter)

2009

• Amasheh M, Grotjohann I, Amasheh S, Fromm A, Söderholm JD, Zeitz M, Fromm M, Schulzke JD (2009) Regulation of mucosal structure and barrier function in rat colon exposed to tumor necrosis factor alpha and interferon gamma in vitro: A novel model for studying the pathomechanisms of inflammatory bowel disease cytokines. Scand. J. Gastroent. 44(10): 1226-1235 [PubMed] [WebPage] [PDF]

• Amasheh S, Dullat S, Fromm M, Schulzke JD, Buhr HJ, Kroesen AJ (2009) Inflamed pouch mucosa possesses altered tight junctions indicating recurrence of inflammatory bowel disease. Int. J. Colorectal Dis. 24(10): 1149-1156 [PubMed] [WebPage] [PDF] 

• Amasheh S*, Milatz S* (*shared first authorship), Krug SM, Bergs M, Amasheh M, Schulzke JD, Fromm M (2009, Epub 08.11.2008) Na⁺ absorption defends from paracellular back-leakage by claudin-8 upregulation. Biochem. Biophys. Res. Comm. 378(1): 45-50 [PubMed] [WebPage] [PDF]

• Bergann T, Plöger S, Fromm A, Zeissig S, Borden SA, Fromm M, Schulzke JD (2009) A colonic mineralocorticoid receptor cell model expressing epithelial Na⁺ channels. Biochem. Biophys. Res. Comm. 381(2): 280-285 [PubMed] [WebPage] [PDF]

• Bergann T, Zeissig S, Fromm A, Richter JF, Fromm M, Schulzke JD (2009) Glucocorticoid and tumor necrosis factor-alpha synergize to induce absorption by the epithelial sodium channel in the colon. Gastroenterology 136(3): 933-942 [PubMed] [WebPage] [PDF]

• Bücker R*, Troeger H* (*shared first authorship), Kleer J, Fromm M, Schulzke JD (2009) Arcobacter butzleri induces barrier dysfunction in intestinal epithelial cells. J. Infect. Dis. 200(5): 756-764 [PubMed] [WebPage] [PDF]

• De Santo NG, Fromm M, Russo F, Wiederholt M (2009) Klaus Hierholzer [1929-2007] and his impact on our understanding of the renal effects of steroid hormones. J. Nephrol.  22(S14): 159-178 [PubMed] [PDF]

• Epple HJ, Schneider T, Troeger H, Kunkel D, Allers K, Moos V, Amasheh M, Loddenkemper C, Fromm M, Zeitz M, Schulzke JD (2009) Impairment of the intestinal barrier is evident in untreated but absent in suppressively treated HIV-infected patients. Gut 58: 220-227 [PubMed] [WebPage] [PDF]

• Günzel D, Amasheh S, Pfaffenbach S, Richter JF, Kausalya PJ, Hunziker W, Fromm M (2009) Claudin-16 affects transcellular Cl^- secretion in MDCK cells. J. Physiol. (Lond.) 587(15): 3777-3793 [PubMed] [WebPage] [PDF] [Supplement]

• Günzel D, Stuiver M, Kausalya PJ, Haisch L, Krug SM, Rosenthal R, Meij IC, Hunziker W, Fromm M, Müller D (2009) Claudin-10 exists in six alternatively spliced isoforms which exhibit distinct localization and function. J. Cell Sci. 122: 1507-1517 [PubMed] [WebPage] [PDF]

• Günzel D, Yu ASL (2009, Epub 16.09.2008) Function and regulation of claudins in the thick ascending limb of Henle. Pflügers Arch. 458(1): 77-88 [PubMed] [WebPage] [PDF]

• Krug SM, Amasheh S, Richter JF, Milatz S, Günzel D, Westphal JK, Huber O, Schulzke JD, Fromm M (2009) Tricellulin forms a barrier to macromolecules in tricellular tight junctions without affecting ion permeability. Mol. Biol. Cell 20: 3713-3724 [PubMed] [WebPage] [PDF] [Supplement text] [Supplement video]

 

• Krug SM, Fromm M, Günzel D (2009) Two-path impedance spectroscopy for measuring paracellular and transcellular epithelial resistance. Biophys. J. 97(8): 2202-2211 [PubMed] [WebPage] [PDF] [Supplement]

• Kuhne M, Erben U, Schulze-Tanzil G, Köhler D, Wu P, Richter JF, John T, Radbruch A, Sieper J, Appel H (2009) HLA-B27 restricted antigen presentation by human chondrocytes to CD8+ T cells: potential contribution to local immunpathology in ankylosing spondylitis. Arthritis Rheum. 60(6): 1635-1646 [PubMed] [WebPage] [PDF]

• Mankertz J*, Amasheh M* (*shared first authorship), Krug SM, Fromm A, Amasheh S, Hillenbrand B, Tavalali S, Fromm M, Schulzke JD (2009) TNFalpha up-regulates claudin-2 expression in epithelial HT-29/B6 cells via phosphatidylinositol-3-kinase signaling. Cell Tiss. Res. 336(1): 67-77 [PubMed] [WebPage] [PDF]

• Richter JF, Gitter AH, Günzel D, Weiss S, Mohamed W, Chakraborti T, Fromm M, Schulzke JD (2009) Listeriolysin O affects barrier function and induces chloride secretion in HT-29/B6 colon epithelial cells. Am. J. Physiol. Gastrointest. Liver Physiol. 296(6): G1350-G1359 [PubMed] [WebPage] [PDF]

• Troeger H, Loddenkemper C, Schneider T, Schreier E, Epple HJ, Zeitz M, Fromm M, Schulzke JD (2009) Structural and functional changes of the duodenum in human norovirus infection. Gut 58: 1070-1077 [PubMed] [WebPage] [PDF]

• Yu ASL, Cheng MH, Angelow S, Günzel D, Kanzawa SA, Schneeberger EE, Fromm M, Coalson RD (2009) Molecular basis for cation selectivity in claudin-2-based paracellular pores: Identification of an electrostatic interaction site. J. Gen. Physiol. 133(1): 111-127 [PubMed] [WebPage] [PDF]

• Ziera T, Irlbacher H, Fromm A, Latouche C, Krug SM, Fromm M, Jaisser F, Borden SA (2009) Cnksr3 is a direct mineralocorticoid receptor target gene and plays a key role in the regulation of the epithelial sodium channel. FASEB J. 23(11): 3936-3946 [PubMed] [WebPage] [PDF]

  • Reviews / Textbook chapters

• Amasheh M, Andres S, Amasheh S, Fromm M, Schulzke JD (2009) Barrier effects of nutritional factors. Ann. N.Y. Acad. Sci. 1165: 267-273 [PubMed] [WebPage] [PDF]

• Amasheh S, Milatz S, Krug SM, Markov AG, Günzel D, Amasheh M, Fromm M (2009) Tight junction proteins as channel formers and barrier builders: claudin-2, -5, and -8. Ann. N.Y. Acad. Sci. 1165: 211-219 [PubMed] [WebPage] [PDF]

• Fromm M, Gaebel G (2009) chapter 13: "Niere" [Kidney], In: Physiologie der Haustiere. Engelhardt W von (ed), 3rd fully revised edn, Enke Verlag, Stuttgart, p 292-320 [Publishers ad] (Textbook of veterinary physiology)

• Fromm M, Krug SM, Zeissig S, Richter JF, Rosenthal R, Schulzke JD, Günzel D (2009) High resolution analysis of barrier function. Ann. N.Y. Acad. Sci. 1165: 74-81 [PubMed] [WebPage] [PDF]

• Fromm M, Schulzke JD, Volume Editors (2009) Molecular structure and function of the tight junction. Ann. N.Y. Acad. Sci. 1165, pp 1-346, 46 papers, ISBN 978-1-57331-749-8 [Contents and Full Papers] [Cover]

• Günzel D, Haisch L, Pfaffenbach S, Krug SM, Milatz S, Amasheh S, Hunziker W, Müller D (2009) Claudin function in the thick ascending limb of Henle's loop. Ann. N.Y. Acad. Sci. 1165: 152-162 [PubMed] [WebPage] [PDF]

• Schulzke JD, Fromm M (2009) Tight junctions: Molecular structure meets function. Ann. N.Y. Acad. Sci. 1165: 1-6 [PubMed] [WebPage] [PDF]

• Schulzke JD*, Ploeger S* (*shared first authorship), Amasheh M, Fromm A, Zeissig S, Troeger H, Richter JF, Bojarski C, Schumann M, Fromm M (2009) Epithelial tight junctions in intestinal inflammation. Ann. N.Y. Acad. Sci. 1165: 294-300 [PubMed] [WebPage] [PDF]

2008

• Amasheh M, Schlichter S, Amasheh S, Mankertz J, Zeitz M, Fromm M, Schulzke JD (2008) Quercetin enhances epithelial barrier function and increases claudin-4 expression in Caco-2 cells. J. Nutr.  138(6): 1067-1073 [PubMed] [WebPage] [PDF]

• Heller F, Fromm A, Gitter AH, Mankertz J, Schulzke JD (2008) Epithelial apoptosis is a prominent feature of the epithelial barrier disturbance in intestinal inflammation: effect of pro-inflammatory interleukin-13 on epithelial cell function. Mucosal Immun. 1: S58-S61 [PubMed] [WebPage] [PDF]

• Kroesen AJ, Dullat S, Schulzke JD, Fromm M, Buhr HJ (2008) Permanently increased mucosal permeability in patients with backwashileitis after ileoanal pouch for ulcerative colitis. Scand. J. Gastroent. 43(6): 704-711 [PubMed] [WebPage] [PDF]

• Renieri G, Choritz L, Rosenthal R, Meissner S, Pfeiffer N, Thieme H (2008) Effects of endothelin-1 on calcium-independent contraction of bovine trabecular meshwork. Graefes Arch. Clin. Exp. Ophthalmol. 246(8): 1107-1115 [PubMed] [WebPage] [PDF]

• Schumann M, Richter JF, Wedell I, Moos V, Zimmermann-Kordmann M, Schneider T, Daum S, Zeitz M, Fromm M, Schulzke JD (2008) Mechanisms of epithelial translocation of the a2-gliadin-33mer in celiac sprue. Gut 57(6): 747-754 [PubMed] [WebPage] [PDF]

• Thumfart J, Jung S, Amasheh S, Krämer S, Peters H, Sommer K, Biber J, Murer H, Meij I, Querfeld U, Wagner CA, Müller D (2008) Magnesium stimulates renal phosphate reabsorption. Am. J. Physiol. Renal Physiol. 295(4): F1126-F1133 [PubMed] [WebPage] [PDF]

• Will C, Fromm M, Müller D (2008) Claudin tight junction proteins: novel aspects in paracellular transport. Periton. Dialysis Int. 28(6): 577-584 [PubMed] [PDF]

• Wimmers S, Coeppicus L, Rosenthal R, Strauss O (2008) Expression profile of voltage-dependent Ca²⁺ channel subunits in the human retinal pigment epithelium. Graefes Arch. Clin. Exp. Ophthalmol. 246(5): 685-692 [PubMed] [WebPage] [PDF]

• Zeissig S, Bergann T, Fromm A, Bojarski C, Heller F, Guenther U, Zeitz M, Fromm M, Schulzke JD (2008) Altered ENaC expression leads to impaired sodium absorption in the non-inflamed intestine in Crohn's disease. Gastroenterology 134(5): 1436-1447 [PubMed] [WebPage] [PDF]

  • Book

• De Santo NG, Fromm M, Russo F, Wiederholt M (2008) Klaus Hierholzer in memoriam: Klaus Hierholzer and his impact on the renal effects of steroid hormones. Arte Tipografica, Napoli, ISBN 978-88-89776-97-1, pp 48.

  • Textbook chapters

• Fromm M, Schulzke JD (2008) Diarrhea. In: Encyclopedia of molecular mechanisms of disease. Lang F (ed), Springer, Berlin Heidelberg, ISBN 978-3-540-67136-7 (Print) 978-3-540-29676-8 (Online), Part 4, p 528-530. [Online entry] [WebPage]

• Schulzke JD, Fromm M (2008) Malabsorption. In: Encyclopedia of molecular mechanisms of disease. Lang F (ed), Springer, Berlin Heidelberg, ISBN 978-3-540-67136-7 (Print) 978-3-540-29676-8 (Online), Part 13, p 1250-1252. [Online entry] [WebPage]

2007

• Gabriel TE, Günzel D (2007) Quantification of Mg²⁺ extrusion and cytosolic Mg²⁺-buffering in Xenopus oocytes. Arch. Biochem. Biophys. 458(1): 3-15 [PubMed] [WebPage] [PDF]

• Markov AG, Veshnyakova A, Krug SM, Milatz S (2007) Expression of tight junction proteins in the epithelium of small intestine of the rat. Russ. J. Physiol. (Ross. Fiziol. Zh. Im. I. M. Sechenova) 93(9): 1043-1054 [PubMed]

• Mousa SA, Bopaiah CP, Richter JF, Yamdeu RS, Schäfer M (2007) Inhibition of inflammatory pain by CRF at peripheral, spinal and supraspinal sites: involvement of areas coexpressing CRF receptors and opioid peptides. Neuropsychopharmacology doi:10.1038/sj.npp.1301393, p 1-13 [PubMed] [Full paper ahead online]

• Rittner HL, Labuz D, Richter JF, Brack A, Schäfer M, Stein C, Mousa SA (2007) CXCR1/2 ligands induce p38 MAPK-dependent translocation and release of opioid peptides from primary granules in vitro and in vivo. Brain Behav. Immun. 21(8): 1021-3102 [PubMed] [Full paper+links WebPage] [PDF]

• Rosenthal R, Choritz L, Zorn R, Münzer G, Fromm M, Pfeiffer N, Thieme H (2007) Endothelin receptor B in trabecular meshwork. Exp. Eye Res. 85: 482-491 [PubMed] [Full paper+links WebPage] [PDF]

• Rosenthal R, Heimann H, Agostini H, Martin G, Hansen LL, Strauss O (2007) Ca²⁺ channels in retinal pigment epithelial cells regulate VEGF secretion rates in health and disease. Mol. Vision 13: 443-456 [PubMed] [WebPage] [PDF]

• Troeger H, Epple HJ, Schneider T, Wahnschaffe U, Ullrich R, Burchard GD, Jelinek T, Zeitz M, Fromm M, Schulzke JD (2007) Effect of chronic Giardia lamblia infection on epithelial transport and barrier function in human duodenum. Gut 56(3): 328-335 [PubMed] [WebPage] [PDF]  Comment in: Gut 2007 56(3): 316-317

• Troeger H*, Richter JF* (*shared first authorship), Beutin L, Günzel D, Dobrindt U, Epple HJ, Gitter AH, Zeitz M, Fromm M, Schulzke JD (2007) E. coli alpha-hemolysin induces focal leaks in colonic epithelium – a novel mechanism of bacterial translocation. Cell. Microbiol. 9(10): 2530-2540 [PubMed] [WebPage] [PDF]

• Zeissig S, Bürgel N, Günzel D, Richter JF, Mankertz J, Wahnschaffe U, Kroesen AJ, Zeitz M, Fromm M, Schulzke JD (2007) Changes in expression and distribution of claudin-2, -5 and -8 lead to discontinuous tight junctions and barrier dysfunction in active Crohn's disease. Gut 56(1): 61-72 [PubMed] [WebPage] [PDF]

• Zeissig S, Fromm A, Mankertz J, Weiske J, Zeitz M, Fromm M, Schulzke JD (2007) Butyrate induces intestinal sodium absorption via Sp3-mediated transcriptional up-regulation of epithelial sodium channels. Gastroenterology 132(1): 236-248 [PubMed] [WebPage] [PDF]

  • Textbook chapters

• Fromm M (2007) {Numerous key words}, In: Pschyrembel, Klinisches Wörterbuch. Pschyrembel W (Hrsg.), 261. Auflage, deGruyter, Berlin. Book: ISBN 978-3-11-018534-8, CD-ROM: ISBN 978-3-11-019126-4, Book plus CD-ROM: ISBN 978-3-11-019127-1 [Medical dictionary] [Publisher's ad] [Online version]

• Fromm M (2007) Chapter 3: "Transport in Membranen und Epithelien", In: Physiologie des Menschen mit Pathophysiologie. Schmidt RF, Lang F (Hrsg.), 30. Auflage, Springer, Berlin Heidelberg NewYork. ISBN 978-3-540-32908-4, p 41-54 and 971-973 [Textbook of Physiology] [Publisher's ad]

2006

• Ebel H, Günther T (2006) Stimulation of choline/Mg²⁺ antiport in rat erythrocytes by mefloquine. Magnesium Res. 19(1): 7-11 [PubMed] [Full text] [PDF]

• Günzel D*, Florian P* (*shared first authorship), Richter JF, Troeger H, Schulzke JD, Fromm M, Gitter AH (2006) Restitution of single-cell defects in the mouse colon epithelium differs from that of cultured cells. Am. J. Physiol. - Reg. Integ. Comp. Physiol. 290: R1496-R1507 [PubMed] [WebPage] [PDF] [Supplemental videos]

• Günzel D, Kucharski LM, Kehres DG, Romero MF, Maguire ME (2006) The MgtC virulence factor of Salmonella enterica serovar typhimurium activates Na⁺,K⁺-ATPase. J. Bacteriol. 188(15): 5586-5594 [PubMed] [WebPage] [PDF]

• Kausalya PJ*, Amasheh S* (*shared first authorship), Günzel D, Wurps H, Müller D, Fromm M, Hunziker W (2006) Disease-associated mutations affect intracellular traffic and paracellular Mg²⁺ transport function of claudin-16. J. Clin. Invest. 116(4): 878-891 [PubMed] [WebPage] [PDF]

• Kroesen AJ, Leistenschneider P, Lehmann K, Ransco C, Dullat S, Blaut M, Schulzke JD, Fromm M, Buhr HJ (2006) Increased bacterial permeation in long-lasting ileoanal pouches. Inflamm. Bowel Dis. 12(8): 736-744 [PubMed] [WebPage and PDF]

• Markov AG, Shadrin LV, Veshnyakova A, Amasheh S, Fromm M (2006) The tight junction proteins claudin-2 and -16 expression in mammary epithelium of mice. Russ. J. Physiol. (Ross. Fiziol. Zh. Im. I. M. Sechenova) 92(11): 1382-1386 [PubMed listing]

• Reiter B, Kraft R, Günzel D, Zeissig S, Schulzke JD, Fromm M, Harteneck C (2006) TRPV4-mediated regulation of epithelial permeability. FASEB J. 20: 1802-1812 [PubMed] [WebPage] [PDF]

• Rosenthal R, Bakall B, Peachey N, Wimmers S, Wadelius C, Marmorstein A, Strauss O (2006) Expression of bestrophin-1, the product of the VMD2 gene, modulates voltage-dependent Ca²⁺ channels in retinal pigment epithelial cells. FASEB J. 20(1): 178-180 [PubMed] [WebPage] [PDF]

• Schierack P, Nordhoff M, Pollmann M, Weyrauch KD, Amasheh S, Lodemann U, Jores J, Tachu B, Kleta S, Blikslager A, Tedin K, Wieler LH (2006) Characterization of a porcine intestinal epithelial cell line for in vitro studies of microbial pathogenesis in swine. Histochem. Cell Biol. 125(3): 293-305 [PubMed] [WebPage] [PDF]

• Schulzke JD, Bojarski C, Zeissig S, Heller F, Gitter AH, Fromm M (2006) Disrupted barrier function through epithelial cell apoptosis. Ann. N.Y. Acad. Sci. 1072: 288-299 [PubMed] [PDF] [Publisher's ad]

• Thieme H, Schimmat C, Münzer G, Boxberger M, Fromm M, Pfeiffer N, Rosenthal R (2006) Endothelin-antagonism: effects of FP receptor agonists prostaglandin F2a and fluprostenol on trabecular meshwork contractility. Invest. Ophth. Vis. Sci. 47(3): 938-945 [PubMed] [WebPage] [PDF]

• Wollmann G, Lenzner S, Berger W, Rosenthal R, Karl MO, Strauss O (2006) Voltage-dependent ion channels in the mouse RPE: Comparison with Norrie disease mice. Vision Res. 46(5): 688-698 [PubMed] [WebPage] [PDF]

• Zeissig S, Fromm A, Mankertz J, Zeitz M, Fromm M, Schulzke JD (2006) Restoration of ENaC expression by glucocorticoid receptor transfection in human HT-29/B6 colon cells. Biochem. Biophys. Res. Commun. 344(4): 1065-1070 [PubMed] [WebPage] [PDF] 

  • Textbook chapter

• Häussinger D, Fromm M, Tauber R (2006) Chapter 3: "Proteinstoffwechsel", In: Klinische Pathophysiologie. Siegenthaler W, Blum HE, ed., 9^th edtn., Thieme Verlag, Stuttgart, p 108-128 [Textbook of Pathophysiology] [Verlagsprospekt / publisher's ad]

2005

• Amasheh S, Schmidt T, Mahn M, Florian P, Mankertz J, Tavalali S, Gitter AH, Schulzke JD, Fromm M (2005) Contribution of claudin-5 to barrier properties in tight junctions of epithelial cells. Cell Tiss. Res. 321(1): 89-96 [PubMed] [WebPage] [PDF]

• Bode H, Lenzner L, Kraemer OH, Bendfeldt K, Schulzke JD, Fromm M, Stoltenburg-Didinger G, Zeitz M, Ullrich R (2005) The HIV protease inhibitors saquinavir, ritonavir, and nelfinavir induce apoptosis and decrease barrier function in human intestinal epithelial cells. Antivir. Ther. 10(5): 645-655 [PubMed] [PDF]

• Choritz L, Rosenthal R, Fromm M, Foerster MH, Thieme H (2005) Pharmacological and functional characterization of endothelin receptors in bovine trabecular meshwork and ciliary muscle. Ophthalm. Res. 37(4): 179-187 [PubMed] [PDF]

• Ebel H, Günther T (2005) Na⁺/Mg²⁺ antiport in erythrocytes of spontaneously hypertensive rats: role of Mg²⁺ in the pathogenesis of hypertension. Magnesium Res. 18(3): 175-185 [PubMed] [PDF]

• Günzel D, Hintz K, Durry S, Schlue WR (2005) Mg²⁺-malate co-transport, a mechanism for Na⁺-independent Mg²⁺ transport in neurons of the leech Hirudo medicinalis. J. Neurophysiol. 94: 441-453 [PubMed] [WebPage] [PDF]

• Günzel D, McGuigan JAS, Schlue WR (2005) Use of Mg²⁺ and Ca²⁺ macroelectrodes to measure binding in extracellular-like physiological solutions. Front. Biosci. 10: 905-918 [PubMed] [Full text] [Request text]

• Heller F, Florian P, Bojarski C, Richter JF, Christ M, Hillenbrand B, Mankertz J, Gitter AH, Bürgel N, Fromm M, Zeitz M, Fuss I, Strober W, Schulzke JD (2005) Interleukin-13 is the key effector Th2 cytokine in ulcerative colitis that affects epithelial tight junctions, apoptosis and cell restitution. Gastroenterology 129(2): 550-564 [PubMed] [WebPage] [PDF]

• Rosenthal R, Choritz L, Schlott S, Bechrakis NE, Jaroszewski J, Wiederholt M, Thieme H (2005) Effects of ML-7 and Y-27632 on carbachol- and endothelin-1-induced contraction of bovine trabecular meshwork. Exp. Eye Res. 80(6): 837-845 [PubMed] [WebPage] [PDF]

• Rosenthal R, Malek G, Salomon N, Peill-Meininghaus M, Coeppicus L, Wohlleben H, Wimmers S, Bowes Rickman C, Strauss O (2005) The fibroblast growth factor receptors, FGFR-1 and FGFR-2, mediate two independent signalling pathways in human retinal pigment epithelial cells. Biochem. Biophys. Res. Commun. 337(1): 241-247 [PubMed] [WebPage] [PDF]

• Russo JM, Florian P, Shen L, Graham WV, Tretiakova MS, Gitter AH, Mrsny RJ, Turner JR (2005) Distinct temporal-spatial roles for rho kinase and myosin light chain kinase in epithelial purse-string wound closure. Gastroenterology 128(4): 987-1001 [PubMed] [WebPage] [PDF]

• Schulzke JD, Gitter AH, Mankertz J, Spiegel S, Seidler U, Amasheh S, Saitou M, Tsukita S, Fromm M (2005) Epithelial transport and barrier function in occludin-deficient mice. Biochim. Biophys. Acta - Biomembranes 1669(1): 34-42 [PubMed] [WebPage] [PDF]

• Strauss O, Rosenthal R (2005) Funktion des Bestrophins. Ophthalmologe 102(2): 122-126 [PubMed] [WebPage] [PDF]

• Stumpff F, Boxberger M, Krauss A, Rosenthal R, Meissner S, Choritz L, Wiederholt M, Thieme H  (2005) Stimulation of cannabinoid (CB1) and prostanoid (EP2) receptors opens BKCa channels and relaxes ocular trabecular meshwork. Exp. Eye Res. 80(5): 697-708 [PubMed] [WebPage] [PDF]

• Thieme H, Steinhausen K, Ottlecz A, Lambrou GN, Strauss O, Wiederholt M, Rosenthal R (2005) Effects of uroprostone and endothelin-1 on L-type channel currents in human trabecular meshwork cells. Ophthalm. Res. 37(6): 293-300 [PubMed] [PDF]

• Tunggal JA*, Helfrich I* (*shared first authorship), Schmitz A, Schwarz H, Günzel D, Fromm M, Kemler R, Krieg T, Niessen CM (2005) E-cadherin is essential for in vivo epidermal barrier function by regulating tight junctions. EMBO J.  24: 1146-1156 [PubMed] [WebPage] [PDF]

  • Textbook chapters

• Fromm M (2005) Chapter 3: "Transport in Membranen und Epithelien", In: Physiologie des Menschen. Schmidt RF, Lang F, Thews G (Hrsg.), 29. Auflage, Springer, Berlin Heidelberg NewYork. ISBN 3-540-21882-3, p 39-55 [Textbook of Physiology] [Publisher's ad]
  and in: Physiologie des Menschen, Die Bilder-CD-ROM 2.0, Schmidt RF, Lang F, Thews G (Hrsg.), Version 2.0, ISBN 3-540-21919-6 [Publisher's ad]

• Fromm M, Gaebel G (2005) Chapter 13: "Niere", In: Physiologie der Haustiere. Engelhardt W von, Breves G (Hrsg.), 2. Auflage, Enke Verlag, Stuttgart, p 277-303 [Textbook of Veterinary Physiology] [Publisher's ad]

2004

• Amasheh S, Barmeyer C, Koch CS, Tavalali S, Mankertz J, Epple HJ, Gehring MM, Florian P, Kroesen AJ, Zeitz M, Fromm M, Schulzke JD (2004) Cytokine-dependent transcriptional down-regulation of epithelial sodium channel (ENaC) in ulcerative colitis. Gastroenterology 126: 1711-1720  [PubMed] [WebPage] [PDF]

• Barmeyer C*, Amasheh S* (*shared first authorship), Tavalali S, Mankertz J, Zeitz M, Fromm M, Schulzke JD (2004) IL-1beta and TNFalpha regulate sodium absorption in rat distal colon. Biochem. Biophys. Res. Comm. 317: 500-507 [PubMed] [WebPage] [PDF]

• Barmeyer C, Harren M, Schmitz H, Heinzel-Pleines U, Mankertz J, Seidler U, Horak I, Wiedenmann B, Fromm M, Schulzke JD (2004) Mechanisms of diarrhea in the interleukin-2 deficient mouse model of colonic inflammation. Am. J. Physiol. Gastrointest. Liver Physiol. 286: G244-G252 [PubMed] [WebPage] [PDF]

• Bojarski C, Weiske J, Schöneberg T, Schröder W, Mankertz J, Schulzke JD, Florian P, Fromm M, Tauber R, Huber O (2004) The specific fate of tight junction proteins in apoptotic epithelial cells. J. Cell Sci. 117: 2097-2107 [PubMed] [WebPage] [PDF]

• Ebel H, Hollstein M, Günther T (2004) Differential effect of imipramine and related compounds on Mg²⁺ efflux from rat erythrocytes. Biochim. Biophys. Acta - Biomembranes 1667(2):132-140 [PubMed] [WebPage] [PDF]

• Ebel H, Kreis K, Günther T (2004) Regulation of Na⁺/Mg²⁺ antiport in rat erythrocytes. Biochim. Biophys. Acta - Biomembranes 1664(2): 150-160 [PubMed] [WebPage] [PDF]

• Epple HJ, Mankertz J, Ignatius R, Liesenfeld O, Fromm M, Zeitz M, Chakraborty T, Schulzke JD (2004) Aeromonas hydrophila beta-hemolysin induces active chloride secretion in colon epithelial cells (HT-29/B6). Infect. Immun. 72(8): 4848-4858 [PubMed] [WebPage] [PDF]

• Lipka C, Mankertz J, Fromm M, Bühler H, Kühn W, Ragosch V, Hundertmark S (2004) Impairment of the antiproliferative effect of glucocorticosteroids by 11beta-hydroxysteroid dehydrogenase type 2 overexpression in MCF-7 breast cancer cells. Hormone Metab. Res. 36: 437-444 [PubMed] [WebPage] [PDF]

• Mankertz J*, Hillenbrand B* (*shared first authorship), Tavalali S, Huber O, Fromm M, Schulzke JD (2004) Functional crosstalk between Wnt signaling and Cdx-related transcriptional activation in the regulation of the claudin-2 promoter activity. Biochem. Biophys. Res. Comm. 314(4): 1001-1007 [PubMed] [WebPage] [PDF]

• Rosenthal R, Wohlleben H, Malek G, Schlichting L, Thieme H, Bowes Rickman C, Strauss O (2004) Insulin-like growth factor-1 contributes to neovascularization in age-related macular degeneration. Biochem. Biophys. Res. Comm. 323: 1203-1208 [PubMed] [WebPage] [PDF]

• Zeissig S*, Bojarski C* (*shared first authorship), Bürgel N, Mankertz J, Zeitz M, Fromm M, Schulzke JD (2004) Downregulation of epithelial apoptosis and barrier repair in active Crohn's disease by TNFalpha antibody treatment. Gut 53: 1295-1302 [PubMed] [WebPage] [PDF]

2003

• Barmeyer C, Horak I, Zeitz M, Fromm M, Schulzke JD (2003) The Interleukin-2-deficient mouse model. Pathobiology 70(3): 139-142 [PubMed] [Full text]

• Ebel H, Günther T (2003) Stimulation of Na⁺/Mg²⁺ antiport in rat erythrocytes by intracellular Cl^-. FEBS Letters 543: 103-107 [PubMed] [WebPage] [PDF]

• Fidzinski P, Knoll A, Rosenthal R, Schrey A, Vescovi A, Koert U, Wiederholt M, Strauß O (2003) Electrophysiological response of cultured trabecular meshwork cells to synthetic ion channels. Chem. Biol. 10(1): 35-43 [PubMed] [Full text]

• Florian P, Amasheh S, Lessidrensky M, Todt I, Bloedow A, Ernst A, Fromm M, Gitter AH (2003) Claudins in the tight junctions of stria vascularis marginal cells. Biochem. Biophys. Res. Comm. 304: 5-10 [PubMed] [WebPage] [PDF]

• Hierholzer K, Hierholzer J (2003) Forgotten nephrologists: Leonhard Thurneysser and Hermann Senator. J. Nephrol. 16(5): 760-765 [PubMed] [Full text] [Related articles]

• Müller A, Günzel D, Schlue WR (2003) Activation of AMPA/kainate receptors but not acetylcholine receptors causes Mg²⁺ influx into Retzius neurones of the leech Hirudo medicinalis. J. Gen. Physiol. 122: 727-739 [PubMed] [WebPage] [PDF]

• Rosenthal R, Strauss O (2003) Investigations of RPE cells of choroidal neovascular membranes from patients with age-related macula degeneration. Adv. Exp. Med. Biol. 533: 107-113 [PubMed reference]

  • Book edition / Textbook chapter

• Fromm M, ed. (2003) Jahrbuch des Campus Benjamin Franklin, Charité - Universitätsmedizin Berlin / Yearbook of the Campus Benjamin Franklin, Charité - University Medicine Berlin (english summaries), pp 492 [Web edition PDF]

• Hierholzer K, Fromm M (2003) Elementi di physiologia renale. In: Malattie dell' apparato urinario. De Santo NG, Camussi G, D'Armiento M (eds), Editoriale Bios, Cosenza, ISBN 88-7740-353-5, 1st ed, chapter 1, p 3-44 [Chapter "Elements of renal physiology" in Italian textbook "Renal diseases"]

2002

• Grotjohann I, Gräber P (2002) The H⁺-ATPase from chloroplasts: effect of different reconstitution procedures on ATP synthesis activity and on phosphate dependence of ATP synthesis. Biochim. Biophys. Acta - Bioenergetics 1556(2-3): 208-216 [PubMed] [WebPage] [PDF]

• Amasheh S, Meiri N, Gitter AH, Schöneberg T, Mankertz J, Schulzke JD, Fromm M (2002) Claudin-2 expression induces cation-selective channels in tight junctions of epithelial cells. J. Cell Sci. 115(24): 4969-4976 [PubMed] [WebPage] [PDF]

• Bürgel N, Bojarski C, Mankertz J, Zeitz M, Fromm M, Schulzke JD (2002) Mechanisms of diarrhea in collagenous colitis. Gastroenterology 123(2): 433-443 [PubMed] [WebPage] [PDF]

• Ebel H, Hollstein M, Günther T (2002) Role of the choline exchanger in Na⁺-independent Mg²⁺ efflux from rat erythrocytes. Biochim. Biophys. Acta  - Biomembranes 1559(2): 135-144 [PubMed] [WebPage] [PDF]

• Florian P, Schöneberg T, Schulzke JD, Fromm M, Gitter AH (2002) Single-cell epithelial defects close rapidly by an actinomyosin purse string mechanism with functional tight junctions. J. Physiol. (Lond.) 545(2): 485-499 [PubMed] [WebPage] [PDF] [Supplementary movies]

• Hierholzer K, Hierholzer J (2002) The discovery of renal contrast media in Berlin. Am. J. Nephrol. 22(2-3): 295-299 [PubMed] [PDF] [Related articles]

• Kroesen AJ, Stockmann M, Ransco C, Schulzke JD, Fromm M, Buhr HJ (2002) Impairment of epithelial transport but not of barrier function in idiopathic pouchitis after ulcerative colitis. Gut 50(6): 821-826 [PubMed] [Full text]

• Mankertz J, Waller JS, Hillenbrand B, Tavalali S, Florian P, Schöneberg T, Fromm M, Schulzke JD (2002) Gene expression of the tight junction protein occludin includes differential splicing and alternative promoter usage. Biochem. Biophys. Res. Comm. 298: 657-666 [PubMed] [PDF]

• Mergler S, Strauss O (2002) Stimulation of L-type Ca²⁺ channels by increase of intracellular InsP3 in rat retinal pigment epithelial cells. Exp. Eye. Res. 74(1): 29-40 [PubMed] [PDF]

• Schmitz H, Rokos K, Florian P, Gitter AH, Fromm M, Scholz P, Ullrich R, Zeitz M, Pauli G, Schulzke JD (2002) Supernatants of HIV-infected immune cells affect the barrier function of human HT-29/B6 intestinal epithelial cells. AIDS 16(7): 983-991 [PubMed] [WebPage or PDF]

• Strauss O, Rosenthal R, Dey D, Beninde J, Wollmann G, Thieme H, Wiederholt M (2002) Effects of protein kinase C on delayed rectifier K(+) channel regulation by tyrosine kinase in rat retinal pigment epithelial cells. Invest. Ophthalmol. Vis. Sci. 43(5): 1645-1654 [PubMed] [PDF]

• Tebbe B, Mankertz J, Schwarz C, Amasheh S, Fromm M, Schultz-Ehrenburg U, Sánchez Ruderisch H, Schulzke JD, Orfanos CE (2002) Tight junction proteins: A novel class of integral membrane proteins. Expression in human epidermis and HaCaT keratinocytes. Arch. Dermatol. Res. 294: 14-18 [PubMed] [WebPage] [PDF]

  • Review / Book edition

• Rosenthal R, Strauss O (2002) Ca²⁺ channels in the RPE. Adv. Exp. Med. Biol. 514: 225-235 [PubMed reference]

• Fromm M, ed. (2002) Jahrbuch des Fachbereichs Humanmedizin der Freien Universität Berlin / Yearbook of the Medical Faculty (english summaries), pp 494 [Web edition, PDF]

2001

• Bojarski C, Gitter AH, Bendfeldt K, Mankertz J, Schmitz H, Wagner S, Fromm M, Schulzke JD (2001) Permeability of HT-29/B6 colonic epithelium as a function of apoptosis. J. Physiol. (Lond.) 535(2): 541-552 [PubMed] [WebPage] [PDF]

• Epple HJ, Fromm M, Riecken EO, Schulzke JD (2001) Antisecretory effect of loperamide in colon epithelial cells by inhibition of basolateral K⁺ conductance. Scand. J. Gastroent. 36: 731-737 [PubMed] [PDF]

• Gitter AH, Wullstein F, Fromm M, Schulzke JD (2001) Epithelial barrier defects in ulcerative colitis: characterization and quantification by electrophysiological imaging. Gastroenterology 121: 1320-1328 [PubMed] [WebPage] [PDF]

• Hundertmark S, Bühler H, Fromm M, Kruner-Gareis B, Kruner M, Ragosch V, Kuhlmann K, Seckl JR (2001) Ontogeny of 11beta-hydroxysteroid dehydrogenase: activity in the placenta, kidney, colon of fetal rats and rabbits. Horm. Metab. Res. 33(2): 78-83 [PubMed] [WebPage] [PDF]

• Rosenthal R, Thieme H, Strauss O (2001) Fibroblast growth factor receptor 2 (FGFR2) in brain neurons and retinal pigment epithelial cells act via stimulation of neuroendocrine L-type channels (Ca(v)1.3). FASEB J. 15(6): 970-977 [PubMed] [Full text]

• Stumpff F, Boxberger M, Thieme H, Strauss O, Wiederholt M (2001) Flufenamic acid enhances current through maxi-K channels in the trabecular meshwork of the eye. Curr. Eye Res. 22(6): 427-437 [PubMed] [PDF]

• Thieme H, Stumpff F, Ottlecz A, Percicot CL, Lambrou GN, Wiederholt M (2001) Mechanisms of action of unoprostone on trabecular meshwork contractility. Invest. Ophthalmol. Vis. Sci. 42(13): 3193-3201 [PubMed] [WebPage]

• Thieme H, Hildebrand J, Choritz L, Strauss O, Wiederholt M (2001) Muscarinic receptors of the M2 subtype in human and bovine trabecular meshwork. Graefe's Arch. Clin. Exp. Ophthalmol. 239: 310-315 [PubMed] [PDF]

  • Review / Textbook chapter / Book edition

• Schulzke JD, Fromm M (2001) Tight junctions in intestinal inflammation. In: Tight junctions, 2^nd edn., Anderson J, Cereijido M, eds., CRC Press, Boca Raton, ISBN 0-8493-2383-5, p 553-574 [Publisher's ad] [Retailer's ad]

• Häussinger D, Fromm M, Tauber R (2001) Chapter 3: "Proteinstoffwechsel", In: Klinische Pathophysiologie. Siegenthaler W, ed., 8^th edtn., Thieme Verlag, Stuttgart, p 105-125 [Textbook of Pathophysiology]

• Fromm M, ed. (2001) Jahrbuch des Fachbereichs Humanmedizin der Freien Universität Berlin / Yearbook of the Medical Faculty (english summaries), pp 489 [Web edition, PDF]

2000

• Bojarski C, Epple HJ, Kirstein FW, Fromm M, Bisson S, Riecken EO, Schulzke JD (2000) Patients with dyspepsia benefit from eradication of Helicobacter pylori if other organic causes for dyspepsia were carefully ruled out. Z. Gastroenterol. 38(3): 211-219 [PubMed]

• Epple HJ, Amasheh S, Mankertz J, Goltz M, Schulzke JD, Fromm M (2000) Early aldosterone effect in distal colon by transcriptional regulation of ENaC subunits. Am. J. Physiol. 278(5): G718-G724 [PubMed] [WebPage] [PDF]

• Gitter AH, Bendfeldt K, Schmitz H, Schulzke JD, Bentzel CJ, Fromm M (2000) Epithelial barrier defects in HT-29/B6 colonic cell monolayers induced by tumor necrosis factor-alpha. Ann. N.Y. Acad. Sci. 915: 193-203. [PubMed] [Full text]

• Gitter AH, Bendfeldt K, Schulzke JD, Fromm M (2000) Trans-/paracellular, surface/crypt, and epithelial/subepithelial resistances of mammalian colonic epithelia. Pflügers Arch. 439(4): 477-482 [PubMed] [PDF] [Related articles]

• Gitter AH, Bendfeldt K, Schulzke JD, Fromm M (2000) Leaks in the epithelial barrier caused by spontaneous and TNFa-induced single-cell apoptosis. FASEB J. 14(12): 1749-1753 [PubMed] [WebPage] [PDF]

• Mankertz J, Tavalali S, Schmitz H, Mankertz A, Riecken EO, Fromm M, Schulzke JD (2000) Expression from the human occludin promoter is affected by tumor necrosis factor a and interferon g. J. Cell Sci. 113(Pt 11): 2085-2090 [PubMed] [PDF] [GenBank: Homo sapiens occludin gene, partial sequence]

• Saitou M, Furuse M, Sasaki H, Schulzke JD, Fromm M, Takano H, Noda T, Tsukita S (2000) Complex phenotype of mice lacking occludin, a component of tight junction strands. Mol. Biol. Cell 11(12): 4131-4142 [PubMed] [WebPage] [PDF]

• Steinhausen K, Stumpff F, Strauss O, Thieme H, Wiederholt M (2000) Influence of muscarinic agonists and tyrosine kinase inhibitors on L-type Ca²⁺ channels in bovine and human trabecular meshwork cells. Exp. Eye Res. 70(3): 285-293 [PubMed] [PDF]

• Strauss O, Buss F, Rosenthal R, Fischer D, Mergler S, Stumpff F, Thieme H (2000) Activation of neuroendocrine L-type channels (a1D subunits) in retinal pigment epithelial cells and brain neurons by pp60c-src. Biochem. Biophys. Res. Comm. 270(3): 806-810 [PubMed]

• Thieme H, Nuskovski M, Nass JU, Pleyer U, Strauss O, Wiederholt M (2000) Mediation of calcium-independent contraction in trabecular meshwork through protein kinase C and rho-A. Invest. Ophthalmol. Vis. Sci. 41(13): 4240-4246 [PubMed] [WebPage]

  • Reviews / Textbook chapters / Book edition

• Stumpff F, Wiederholt M (2000) Regulation of trabecular meshwork contractility. Ophthalmologica 214(1): 33-53 [PubMed]

• Wiederholt M, Stumpff F, Dörschner N (2000) Contractility of trabecular meshwork and ciliary muscle is modulated by the NO/cGMP system. In: Nitric oxide in the eye. Ed. S. Kashii, Springer Verlag, Tokyo, pp. 15-30

• Wiederholt M, Thieme H, Stumpff F (2000) The regulation of trabecular meshwork and ciliary muscle contractility. Progr. Ret. Eye Res. 19(3): 271-295 [PubMed] [WebPage] [PDF]

• Fromm M, ed. (2000) Jahrbuch des Fachbereichs Humanmedizin der Freien Universität Berlin / Yearbook of the Medical Faculty (english summaries), pp 471 [Web edition, PDF]

• Fromm M, Hierholzer K (2000) Niere. In: Physiologie der Haustiere. W.v. Engelhardt, G. Breves (eds.), 1st edition, Enke, Stuttgart, chapter 12, p 254-288 [Textbook of Veterinary Physiology]

• Fromm M, Hierholzer K (2000) Chapter 34: "Epithelien", In: Physiologie des Menschen. R.F. Schmidt, G. Thews, F. Lang, eds., 28. Auflage, Springer, Berlin Heidelberg New York, pp 719-736 [Textbook of Physiology]

• Lang F, Fromm M (2000) Chapter 35: "Funktionen der Niere", In: Physiologie des Menschen. R.F. Schmidt, G. Thews, F. Lang, eds., 28. Auflage, Springer, Berlin Heidelberg New York, pp 737-776 [Textbook of Physiology] [Verlagsprospekt / publisher's ad].

• Schulzke JD, Fromm M, Riecken EO, Binder H, eds. (2000) Epithelial transport and barrier function: pathomechanisms in gastrointestinal disorders. Ann. N.Y. Acad. Sci. 915: 1-375, ISBN 1-57331-259-2 [Own papers within this volume] [Contents & links to full papers]

1999

• Bode H, Schmidt W, Schulzke JD, Fromm M, Zippel T, Wahnschaffe U, Bendfeldt K, Riecken EO, Ullrich R (1999) The HIV protease inhibitors saquinavir, ritonavir, and nelfinavir, but not indinavir, impair the epithelial barrier in the human intestinal cell line HT-29/B6. AIDS 13(18): 2595-2597 [PubMed reference] [PDF] [Related articles]

• Ebel H, Günther T (1999) Characterization of Mg²⁺ efflux from rat erythrocytes non-loaded with Mg²⁺. Biochim. Biophys. Acta - Biomembranes 1421: 353-360 [PubMed] [WebPage] [PDF]

• Fromm M, ed. (1999) Jahrbuch des Fachbereichs Humanmedizin der Freien Universität Berlin / Yearbook of the Medical Faculty (english summaries), pp 525 [Web edition, WebPage] [Web edition, PDF]

• Grotjohann I, Schulzke JD, Fromm M (1999) Electrogenic Na⁺ transport in rat late distal colon by natural and synthetic glucocorticosteroids and their metabolites. Am. J. Physiol. 276: G491-G498 [PubMed] [WebPage] [PDF]

• Hierholzer K, Ullrich KJ (1999) History of renal physiology in germany during the 19^th century. Am. J. Nephrol. 19: 243-256 [PubMed] [WebPage] [PDF] [Related articles]

• Schmitz H, Barmeyer C, Fromm M, Runkel N, Foss HD, Bentzel CJ, Riecken EO, Schulzke JD (1999) Altered tight junction structure contributes to the impaired epithelial barrier function in ulcerative colitis. Gastroenterology 116: 301-309. [PubMed] [WebPage] [PDF] [DCCV-Preis 1999 / award of the DCCV]

• Schmitz H, Fromm M, Bentzel CJ, Scholz P, Detjen K, Mankertz J, Bode H, Epple HJ, Riecken EO, Schulzke JD (1999) Tumor necrosis factor-alpha (TNFa) regulates the epithelial barrier in the human intestinal cell line HT-29/B6. J. Cell Sci. 112: 137-146 [PubMed] [PDF]

• Stockmann M, Gitter AH, Sorgenfrei D, Fromm M, Schulzke JD (1999) Low edge damage container insert that adjusts intestinal forceps biopsies into Ussing chamber systems. Pflügers Arch. 438: 107-112 [PubMed] [PDF]

• Strauss O, Steinhausen K, Mergler S, Stumpff F, Wiederholt M (1999) Involvement of protein tyrosine kinase in the InsP3-induced activation of Ca²⁺-dependent Cl^- currents in cultured cells of the rat retinal pigment epithelium. J. Membr. Biol. 169: 141-153 [PubMed] [PDF]

• Stumpff F, Que Y, Boxberger M, Strauss O, Wiederholt M (1999) Stimulation of maxi-K channels in trabecular meshwork by tyrosine kinase inhibitors. Invest. Ophthalmol. Vis. Sci. 40: 1404-1417 [PubMed]

• Thieme H, Nass JU, Nuskovski M, Bechrakis NE, Stumpff F, Strauss O, Wiederholt M (1999) The effects of Protein Kinase C (PKC) on Trabecular Meshwork and Ciliary Muscle Contractility. Invest. Ophthalmol. Vis. Sci. 40(13): 3254-3261 [PubMed]

• Thieme H, Nass JU, Nuskovski M, Wiederholt M (1999) The effects of the carbonic anhydrase inhibitors methazolamide, diclofenamide and dorzolamide on trabecular meshwork and ciliary muscle contractility. Exp. Eye Res. 69(4): 455-458 [PubMed reference] [PDF]

• Thieme H, Wissinger B, Jandeck C, Christ-Adler M, Kraus H, Kellner U, Foerster MH (1999) A pedigree of Leber's hereditary optic neuropathy (LHON) with visual loss in childhood primarily in girls. Graefes Arch. Clin. Exp. Ophthalmol. 237: 714-719 [PubMed]

• Valtink M, Engelmann K, Strauss O, Krüger R, Loliger C, Ventura AS, Richard G (1999) Physiological features of primary cultures and subcultures of human retinal pigment epithelial cells before and after cryopreservation for cell transplantation. Graefes Arch. Clin. Exp. Ophthalmol. 237(12): 1001-1006 [PubMed]

• Wiederholt M, Bräuer H, Bräuer B (1999) Excerpta ophthalmologica: Bildatlas zur Physiologie und Pathophysiologie der Mikrozirkulation des Auges. Med. Service, München, pp 1-96

• Wiederholt M, Thieme H, Nass JU, Stumpff F (1999) Contractility of the trabecular meshwork: A target of treatment of glaucoma? In: Pathogenesis and risk factors of glaucoma. Eds. E. Gramer, F. Grehn. Springer Verlag, Berlin, Heidelberg, New York, p 108-116

1998

• Bode H, Schmitz H, Fromm M, Scholz P, Riecken EO, Schulzke JD (1998) IL1b and TNFa, but not IFNa, IFNg, IL6 or IL8, are secretory mediators in human distal colon. Cytokine 10: 457-465 [PubMed] [PDF]

• Fey-Lamprecht F, Gross U, Groth TH, Albrecht W, Paul D, Fromm M, Gitter AH (1998) Functionality of MDCK kidney tubular cells on flat polymer membranes for biohybrid kidney. J. Mater. Sci. Mater. Med. 9: 711-715 [PubMed] [PDF]

• Gitter AH, Fromm M, Schulzke JD (1998) Impedance analysis for determination of epithelial and subepithelial resistance in intestinal tissues. J. Biochem. Biophys. Meth. 37: 35-46 [PubMed]

• Grotjohann I, Gitter AH, Köckerling A, Bertog M, Schulzke JD, Fromm M (1998) Localization of cAMP- and aldosterone-induced K⁺ secretion in rat distal colon by conductance scanning. J. Physiol. (Lond.) 507: 561-570 [PubMed] [WebPage] [PDF]

• Hotz HG, Foitzik T, Rohweder J, Schulzke JD, Fromm M, Runkel NSF, Buhr HJ (1998) Intestinal microcirculation and gut permeability in acute pancreatitits: early changes and therapeutic implications. J. Gastrointest. Surg. 2: 518-525 [PubMed]

• Jüttner R, Ebel H (1998) Characterization of Mg²⁺ transport in brush border membrane vesicles of rabbit ileum studied with mag-fura-2. Biochim. Biophys. Acta 1370: 51-63 [PubMed] [WebPage] [PDF]

• Kirstein FW, Epple HJ, Bojarski C, Victor L, Fromm M, Riecken EO, Schulzke JD (1998) Dual versus triple therapy: comparison of 5 antibiotic regimens for eradication of Helicobacter pylori in a prospective, randomized study. Z. Gastroenterol. 36: 803-809 [PubMed]

• Mergler S, Steinhausen K, Wiederholt M, Strauss O (1998) Altered regulation of L-type channels by protein kinase C and protein tyrosine kinases as a pathophysiologic effect in retinal degeneration. FASEB J. 12: 1125-1134 [PubMed] [PDF]

• Schulzke JD, Bentzel CJ, Schulzke I, Riecken EO, Fromm M (1998) Epithelial tight junction structure in the jejunum of children with acute and treated celiac sprue. Pediatric Res. 43: 435-441 [PubMed] [WebPage]

• Stockmann M, Fromm M, Riecken EO, Schulzke JD (1998) Non-malabsorptive mechanisms of diarrhea in HIV infection. Pathobiology 66: 165-169 [PubMed] [PDF]

• Stockmann M, Fromm M, Schmitz H, Schmidt W, Riecken EO, Schulzke JD (1998) Duodenal biopsies of HIV infected patients with diarrhea show epithelial barrier defects but no secretion. AIDS 12: 43-51 [PubMed]

• Strauss O, Steinhausen K, Wienrich M, Wiederholt M (1998) Activation of Cl-conductance by protein kinase-dependent phosphorylation in cultured rat retinal pigment epithelial cells. Exp. Eye Res. 66: 35-42 [PubMed]

• Strauss O, Stumpff F, Mergler S, Wienrich M, Wiederholt M (1998) The Royal College of Surgeons rat: an animal model for inherited retinal degeneration with a still unknown genetical defect. Acta Anatomica 162: 101-111 [PubMed]

• Wiederholt M (1998) Contractility of trabecular meshwork and ciliary muscle: Effects of prostaglandins. In: Prostaglandins in ophthalmology. Ed. M. Diestelhorst, Kaden Verlag, Heidelberg, pp. 31-38

• Wiederholt M (1998) Direct involvement of trabecular meshwork in regulation of aqueous humor outflow. Curr. Opinion Ophthalmol. 9: 46-49 [PubMed]

• Wiederholt M (1998) Nitric oxide and endothelin in aqueous humor outflow regulation. In: Nitric oxide and endothelin in the pathogenesis of glaucoma. Ed. I.O. Haefliger, J. Flammer, Lippincott-Raven Publishers, Philadelphia, p 168-177

• Wiederholt M (1998)  Pharmacological regulation of trabecular meshwork contractility. In: Fortbildung Glaukom, Band 1: Perfusion und Pharmakologie. Eds. K.G. Schmidt, L.E. Pillunat, Enke-Verlag, Stuttgart, p 19-28

• Wiederholt M, Groth J, Strauss O (1998) Protein tyrosine kinase pathways and the regulation of trabecular meshwork and ciliary muscle contractility. Invest. Ophthalmol. Vis. Sci. 39: 1012-1020 [PubMed]

• Wiederholt M, Stumpff F (1998) The trabecular meshwork and aqueous humor reabsorption. In: Current Topics in Membranes, Vol. 45 "The eye's aqueous humor: from secretion to glaucoma", Ed: M.M. Civan, Academic Press, San Diego, pp. 163-202

1997

• Agrawal R, Lichtenstein I, Siebe H, Hierholzer K (1997) In vitro 6 beta-hydroxylation of progesterone in human renal tissue. Wien. Klin. Wochenschr. 109: 493-496 [PubMed]

• Ebel H (1997) [Mg²⁺ transport in the heart. An overview]. Herz 22 Suppl 1: 10-17 [PubMed reference]

• Epple HJ, Kirstein FW, Bojarski C, Frege J, Fromm M, Riecken EO, Schulzke JD (1997) ¹³C-urea breath test in Helicobacter pylori diagnosis and eradication: correlation to histology, origin of "false" results, and influence of food intake. Scand. J. Gastroent. 32: 308-314 [PubMed]

• Epple HJ, Kreusel KM, Hanski C, Schulzke JD, Riecken EO, Fromm M (1997) Differential stimulation of intestinal mucin secretion by cholera toxin and carbachol. Pflügers Arch. 433: 638-647 [PubMed] [PDF]

• Fromm M, Hierholzer K (1995, 1997) Epithelien. In: Physiologie des Menschen. Kapitel 34, R.F. Schmidt und G. Thews eds., 26. und 27. Auflage, Springer, Berlin Heidelberg New York, pp 719-736 [Textbook of Physiology] [Verlagsprospekt / publisher's ad].

• Gabelt BT, Wiederholt M, Clark AF, Kaufman Pl (1997) Anterior segment physiology following bumetanide inhibition of Na⁺, K⁺, Cl^- cotransport. Invest. Ophthalmol. Vis. Sci. 38: 1700-1707 [PubMed]

• Gitter AH, Bertog M, Schulzke JD, Fromm M (1997) Measurement of paracellular epithelial conductivity by conductance scanning. Pflügers Arch. 434: 830-840 [PubMed] [PDF]

• Gitter AH, Schulzke JD, Sorgenfrei D, Fromm M (1997) Ussing chamber for high-frequency transmural impedance analysis of epithelial tissues. J. Biochem. Biophys. Meth. 35: 81-88 [PubMed]

• Foitzik T, Stufler M, Hotz HG, Klinnert J, Wagner J, Warshaw AL, Schulzke JD, Fromm M, Buhr HJ (1997) Glutamine stabilizes intestinal permeability and reduces pancreatic infection in acute experimental pancreatitis. J. Gastrointest. Surg. 1: 40-47 [PubMed]

• Hierholzer K, Finke R (1997) Myxedema. Kidney Int. Suppl. 59: S82-S89 [PubMed]

• Hierholzer K, Fromm M (1995, 1997) Funktionen der Niere. In: Physiologie des Menschen. Kapitel 35, R.F. Schmidt und G. Thews eds., 26. und 27. Auflage, Springer, Berlin Heidelberg New York, pp 737-776 [Textbook of Physiology].

• Hierholzer K, Fromm M (1995, 1997) Elektrolyt- und Wasserhaushalt. In: Physiologie des Menschen. Kapitel 36, R.F. Schmidt und G. Thews eds., 26. und 27. Auflage., Springer, Berlin Heidelberg NewYork, p 778-791 [Textbook of Physiology].

• Hierholzer K, Hierholzer J (1997) Renal imaging techniques. Am. J. Nephrol. 17: 369-381 [PubMed]

• Strauss O, Mergler S, Wiederholt M (1997) Regulation of L-type calcium channels by protein tyrosine kinase (PTK) and protein kinase C (PKC) in cultured rat and human retinal pigment epithelial cells. FASEB J. 11: 859-867 [PubMed]

• Stumpff F, Strauss O, Boxberger M, Wiederholt M (1997) Characterization of maxi-K-channels in trabecular meshwork and their regulation by cGMP. Invest. Ophthalmol. Vis. Sci. 38: 1883-1892 [PubMed]

1996

• Diener M, Bertog M, Fromm M, Scharrer E (1996) Segmental heterogeneity of swelling-induced Cl^- transport in rat small intestine. Pflügers Arch. 432: 293-300 [PubMed] [PDF]

• Hierholzer K, Lichtenstein I, Siebe H (1996) Does corticosteroid metabolism in target organs affect the cardiovascular system? J. Auton. Nerv. Syst. 1996 57: 188-192 [PubMed]

• Lepple-Wienhues A, Berweck S, Böhmig M, Leo CP, Meyling B, Garbe C, Wiederholt M (1996) K⁺ channels and the intracellular calcium signal in human melanoma cell proliferation. J. Membr. Biol. 151, 149–157 [PubMed] [PDF]

• Schmitz H, Fromm M, Bode H, Scholz P, Riecken EO, Schulzke JD (1996) Tumor necrosis factor alpha induces Cl^- and K⁺ secretion in human distal colon driven by prostaglandin E₂. Am. J. Physiol. 271: G669-G674 [PubMed] [PDF]

• Stahl K, Lichtenstein I, Siebe H, Hierholzer K (1996) Interaction of 11 beta-hydroxysteroid-oxido reductase in different organs of various mammalian species. Kidney Int. Suppl. 55: S156-S159 [PubMed]

• Strauss O, Wiederholt M, Wienrich M (1996) Activation of Cl^- currents in cultured rat retinal pigment epithelial cells by intracellular applications of inositol-1,4,5-triphosphate: differences between rats with retinal dystrophy (RCS) and normal rats. J. Membr. Biol. 151: 189-200 [PubMed] [PDF]

1995

• Epple HJ, Schulzke JD, Schmitz H, Fromm M (1995) Enzyme and mineralocorticoid receptor controlled electrogenic Na⁺ absorption in the human rectum, in vitro. Am. J. Physiol. 269: G42-G48 [PubMed] [PDF]

• Kesselhut A, von Bruchhausen F, Ebel H, Rehse K (1995) Platelet aggregation inhibitong and anticoagulant effecs of oligoamines. XXV: Interactions of the oligoamine RE 1492 with biomembranes, Arch. Pharmazie 328: 21-27 [PubMed]

• Noske W, Strauss O, Levarlet B, Wiederholt M, Hirsch M (1995) Incomplete belts of tight junctions in cultured non-pigmented human ciliary epithelial cells. J. Submicrosc. Cytol. Pathol. 27: 1-8 [PubMed]

• Schulzke JD, Riecken EO, Fromm M (1995) Distension-induced electrogenic Cl^- secretion is mediated via VIP-ergic neurons in rat rectal colon. Am. J. Physiol. 268: G725-G731 [PubMed] [PDF]

• Schulzke JD, Schulzke I, Fromm M, Riecken EO (1995) Epithelial barrier and ion transport in celiac sprue: electrical measurements on intestinal aspiration biopsies. Gut 37: 777-782 [PubMed] [PDF]

• Wiederholt M (1995) The ciliary epithelium of the eye as a model for acid-base related transport properties. In: Acid-base and electrolyte balance. Molecular, cellular, and clinical aspects. Eds. N.G. De Santo, G. Capasso, Istituto Italiano per gli Studi Filosofici, pp. 2-8.

• Wiederholt M, Berweck S, Helbig H (1995) Electrophysiological properties of cultured retinal capillary pericytes. In: Progress in Retinal and Eye Research, Vol. 14, No. 2, Eds. N.N. Osborne, G.J. Chader, Pergamon Press, Oxford - New York - Seoul - Tokyo, pp. 437-451.

• Wiederholt M, Bielka S, Schweig F, Lütjen-Drecoll E, Lepple-Wienhues A (1995) Regulation of outflow rate and resistance in the perfused anterior segment of the bovine eye. Exp. Eye Res. 61: 223-234 [PubMed]

1994

• Berweck S, Lepple-Wienhues A, Stöß M, Wiederholt M (1994) Large conductance calcium-activated potassium channels in cultured retinal pericytes under normal and high-glucose conditions. Pflügers Arch. 427: 9-16 [PubMed] [PDF]

• Bühler H, Perschel FH, Fitzner R, Hierholzer K (1994) Endogenous inhibitors of 11 beta-OHSD: existence and possible significance. Steroids 59: 131-135 [PubMed]

• Finke R, Hierholzer K, Schleusener H (1994) The thyroid gland (Thyroid hormones, their origin and their mechanism of action) In: Human Physiology from Cellular Mechanism to Integration. Greger R, Koepchen HP, Mommaerts W, Windhorst U (eds). Part 1, Section D, Chapter 19. Springer Heidelberg New York [Comprehensive textbook of Physiology]

• Fromm M (1994) Störungen der Verdauung und des epithelialen Transports. In: Pathophysiologie des Menschen, Kapitel 6.5, K. Hierholzer und R.F. Schmidt eds., Chapman & Hall, Weinheim, pp 6.28-6.38 [Textbook of Pathophysiology].

• Fromm M, Hegel U, M. Wiederholt (1994) Epithelien. In: Pathophysiologie des Menschen, Kapitel 5, K. Hierholzer und R.F. Schmidt eds., Chapman & Hall, Weinheim, pp 5.1-5.19 [Textbook of Pathophysiology]

• Fromm M, Schulzke JD (1994) Parazellulärer Nährstofftransport: Fakten und Irrtümer [Paracellular sugar transport: facts and doubts]. Z. Gastroent. 32: 30-34 [Review] [Abstract]

• Gogarten W, Köckerling A, Fromm M, Riecken EO, Schulzke JD (1994) Effect of acute Yersinia Enterocolitica infection on intestinal barrier function in the mouse. Scand. J. Gastroent. 29: 814-819 [PubMed]

• Hierholzer K (1994) Carl Ludwig, Jacob Henle, Hermann Helmholtz, Emil DuBois-Reymond and the scientific development of nephrology in Germany. Am. J. Nephrol. 14: 344-354 [PubMed]

• Hierholzer K, Bühler H (1994) The metabolism of cortical hormones and their general mode of action. In: Human Physiology from Cellular Mechanism to Integration. Greger R, Koepchen HP, Mommaerts W, Windhorst U (eds). Part 1, Section D, Chapter 17. Springer Heidelberg NewYork

• Hierholzer K, Fromm M, Ebel H (1994) Elektrolyt- und Wasserhaushalt. In: Pathophysiologie des Menschen. Hierholzer K, Schmidt RF eds., Chapman & Hall, Weinheim, Kap. 10, pp 10.1-10.16 [Textbook of Pathophysiology].

• Hierholzer J, Hierholzer C, Hierholzer K (1994) Johann Lukas Schönlein and his contribution to nephrology and medicine. Am. J. Nephrol. 14: 467-472 [PubMed]

• Hundertmark S, Ragosch V, Schein B, Bühler H, Lorenz U, Fromm M, Weitzel HK (1994) Gestational age dependence of 11b-hydroxysteroid dehydrogenase and its relationship to the enzymes of phosphatidylcholine synthesis in lung and liver of rat. Biochim. Biophys. Acta 1210: 348-354 [PubMed]

• Lepple-Wienhues A, Rauch R, Clark A, Grässmann A, Berweck S, Wiederholt M (1994) Electrophysiological properties of cultured human trabecular meshwork cells. Exp. Eye Res. 59: 305-311 [PubMed]

• Noske W, Fromm M, Levarlet B, Kreusel KM, Hirsch M (1994) Tight junctions of the human corneal endothelium: morphological and electrophysiological features. Ger. J. Ophtalmol. 3: 253-257 [PubMed]

• Noske W, Levarlet B, Kreusel KM, Fromm M, Hirsch M (1994) Tight junctions and paracellular permeability in cultured bovine corneal endothelial cells. Graefes Arch. Clin. Exp. Ophthalmol. 232: 608-613

• Wagner S, Wenzel-Seifert K, Volbracht L, Sorgenfrei D, Ebel H (1994) Oleic acid inhibition of Na⁺/D-glucose transport in isolated renal brush border membranes: role of lipid physical parameters and trans Na⁺-inhibition. Biochim. Biophys. Acta 1190: 309-318 [PubMed]

• Wiederholt M, Sturm A, Lepple-Wienhues A (1994) Relaxation of trabecular meshwork and ciliary muscle by release of nitric oxide. Invest. Ophthalmol. Vis. Sci. 35: 2515-2520 [PubMed]

1993

• Berweck S, Thieme H, Helbig H, Lepple-Wienhues A, Wiederholt M (1993) Effect of elevated glucose concentration on membrane voltage regulation in retinal capillary pericytes. Diabetes 42: 1347-1350 [PubMed]

• Berweck S, Thieme H, Lepple-Wienhues A, Helbig H, Wiederholt M (1993) Insulin-induced hyperpolarization in retinal capillary pericytes. Invest. Ophthalmol. Vis. Sci. 34: 3402-3407 [PubMed]

• Fischer W, Hierholzer K, Hubenstorf M, Walther P, Winau R (Eds) (1993) Exodus der Wissenschaften aus Berlin. Fragestellungen - Ergebnisse - Desiderate. Entwicklungen vor und nach 1933. Forschungsbericht 7, Akademie der Wissenschaften zu Berlin, De Gruyter Verlag, Berlin New York

• Fromm M, Schulzke JD, Hegel U (1993) Control of electrogenic Na⁺ absorption in rat late distal colon by nanomolar aldosterone added in vitro. Am. J. Physiol. 264: E68-E73 [PubMed] [PDF]

• Hegel U, Fromm M, Kreusel KM, Wiederholt M (1993) Bovine and porcine large intestine as model epithelia in a student lab course. Am. J. Physiol. 265: S10-S19 [PubMed] [PDF] (Comment: 1996 we switched to rabbit distal colon which we obtain from a rabbit slaughtery nearby Berlin)

• Hundertmark S, Ragosch V, Schein B, Bühler H, Fromm M, Lorenz U, Weitzel H (1993) 11-beta-hydroxysteroid dehydrogenase of rat lung: enzyme kinetic, oxidase-reductase ratio, electrolyte and trace element dependence. Enzyme Protein 47: 83-91 [PubMed]

• Köckerling A, Sorgenfrei D, Fromm M (1993) Electrogenic Na⁺ absorption of rat distal colon is confined to surface epithelium. A voltage scanning study. Am. J. Physiol. 264: C1285-C1293 [PubMed] [PDF]

• Köckerling A, Fromm M (1993) Origin of cAMP dependent Cl^- secretion from both crypts and surface epithelia of rat intestine. Am. J. Physiol. 264: C1294-C1301. [PubMed] [PDF]

• Sabatini S, Hartsell A, Meyer M, Kurtzman NA, Hierholzer K (1993) Corticosterone metabolism and membrane transport. Miner. Electrolyte Metab. 19: 343-350 [PubMed]

• Siebe H, Baude G, Lichtenstein I, Wang D, Bühler H, Hoyer GA, Hierholzer K (1993) Metabolism of dexamethasone: Sites and activity in mammalian tissues. Renal Physiol. Biochem. 16: 79-88 [PubMed]

• Schulzke JD, Fromm M, Gogarten W, Gebhard H, Schröder P, Riecken EO (1993) Epithelial ion transport in the ileal J-pouch after proctocolectomy in the rat. Scand. J. Gastroent. 28: 533-539 [PubMed]

• Wiederholt M, Helbig H, Korbmacher C (1993) Regulation of electrolyte transport mechanisms in ciliary epithelium. In: Basic aspects of glaucoma research, III, Ed. E. Lütjen-Drecoll. Schattauer, Stuttgart, New York, p 225-241

• Wiederholt M, Lepple-Wienhues A, Stahl F (1993) Contractile properties of trabecular meshwork and ciliary muscle. In: Basic aspects of glaucoma research, III, Ed. E. Lütjen-Drecoll. Schattauer, Stuttgart, New York, p 287-306

1992

• Bentzel CJ, Palant CE, Fromm M (1992) Physiological and pathological factors affecting the tight junction. In: Tight junctions, chapter 11, M. Cereijido ed., CRC Press, Boca Raton, p 151-173 [Review]

• Bühler H, Perschel FH, Hierholzer K (1992) Inhibition of rat 11-hydroxysteroid dehydrogenase by steroidal compounds and triterpenoids; structure-function relationship. Biochim. Biophys. Acta 1075: 206-212 [PubMed]

• Fischer H, Kreusel KM, Illek B, Machen TE, Hegel U, Clauss W (1992) The outwardly rectifying Cl^- channel is not involved in cAMP-mediated Cl^- secretion in HT-29 cells: evidence for a very-low-conductance Cl^- channel. Pflügers Arch. 422: 159-167 [PubMed] [PDF]

• Helbig H, Kornacker S, Berweck S, Stahl F, Lepple-Wienhues A, Wiederholt M (1992) Membrane potentials in retinal capillary pericytes: Excitability and effect of vasoactive sustances. Invest. Ophthalmol. Vis. Sci. 33: 2105-2112 [PubMed]

• Hierholzer K (1992) Claude Bernard, Portrait. Forschung und Medizin, Botschaften Schering AG 1: 99-105

• Hierholzer K, Winau R (1992) Pioneer Nephrologists of Berlin. Am. J. Nephrol. 12: 442-450 [PubMed reference]

• Illek B, Fischer H, Kreusel KM, Hegel U, Clauss W (1992) Volume-sensitive basolateral K⁺ channels in HT-29/B6 cells: block by lidocaine, quinidine, NPPB, and Ba²⁺. Am. J. Physiol. 263: C674-C683 [PubMed] [PDF]

• Lepple-Wienhues A, Becker M, Stahl F, Berweck S, Hensen J, Noske W, Eichhorn M, Wiederholt M (1992) Endothelin-like immunoreactivity in the aqueous humour and in conditioned medium from cultured ciliary epithelial cells. Curr. Eye Res. 11: 1041-1046 [PubMed]

• Lepple-Wienhues A, Stahl F, Wunderling D, Wiederholt M (1992) Effects of endothelin and calcium channel blockers on membrane voltage and intracellular calcium in cultured bovine trabecular meshwork. German J. Ophthalmol. 1: 159-163 [PubMed]

• Schulzke JD, Fromm M, Bentzel CJ, Zeitz M, Menge H, Riecken EO (1992) Ion transport in the experimental short bowel syndrome of the rat: increased glucose-dependent Na-absorption is the main adaptive response. Gastroenterology 102: 497-504 [PubMed] [PDF]

• Stahl F, Garus HJ, Lepple-Wienhues A, Wiederholt M (1992) Effect of histamine on membrane potential of cultured human nonpigmented ciliary epithelial cells. German J. Ophthalmol. 1: 62-66 [PubMed]

• Stahl F, Gebauer B, Lepple-Wienhues A, Langenbeck-Groh G, Berweck S, Wiederholt M (1992) Characterization of acetylcholine- and endothelin-induced calcium entry in human ciliary muscle cells. Pflügers Arch. 422: 105-111 [PubMed] [PDF]

• Stahl F, Lepple-Wienhues A, Koch M, Wiederholt M (1992) Na⁺-dependent HCO₃^- transport and Na⁺/H⁺ exchange regulate pH_i in human ciliary muscle cells. J. Membr. Biol. 127: 215-225 [PubMed] [PDF]

• Stahl F, Lepple-Wienhues A, Kuppinger M, Tamm E, Wiederholt M (1992) Electrogenic sodium-bicarbonate cotransport in human ciliary muscle cells. Am. J. Physiol. 262: C427-C435 [PubMed] [PDF]

• Strauss O, Stahl F, Wiederholt M (1992) Elevation of cytosolic free calcium in cultured ciliary epithelial cells by histamine: effects of verapamil and staurosporine. J. Ocular Pharmacol. 8: 359-366 [PubMed]

• Wiek J, Krause M, Schade M, Wiederholt M, Hansen LL (1992) Haemorheological parameters in patients with retinal artery occlusion and anterior ischemic optic neuropathy. Brit. J. Ophthalmol. 76: 142-145 [PubMed]

1991

• Coroneo MT, Korbmacher C, Stiemer B, Flügel C, Lütjen-Drecoll E, Wiederholt M (1991) Electrical and morphological evidence for heterogenous populations of cultured bovine trabecular meshwork cells. Exp. Eye Res. 52: 375-388 [PubMed]

• Ebel H, Strauss D, Christowa M, Papanis B (1991) Na⁺-dependent D-glucose transport in Mg-deficient rat renal brush border membranes. In: Magnesium. A Relevant Ion, Eds. B. Laserre and J. Durlach, J. Libbey, London, pp. 321-325 [Book article]

• Fromm M, Hegel U, Wiederholt M (1991) Epithelien. In: Pathophysiologie des Menschen, Kapitel 5, K. Hierholzer und R.F. Schmidt eds., edition medizin VCH, Weinheim, S. 5.1-5.19 [Textbook of Pathophysiology]

• Hierholzer K, Fromm M, Ebel H (1991) Elektrolyt- und Wasserhaushalt. In: Pathophysiologie des Menschen. VCH Verlagsgesellschaft. Herausgeber: Hierholzer K und Schmidt RF, edition medizin VCH, Weinheim, Kap.10, pp 10.1-10.16 [Textbook of Pathophysiology]

• Hierholzer K, Hierholzer C (1991) J.S. Bach, "Die Kunst der Fuge", BWV 1080, Begleittext für Berliner Saxophon Quartett, Classic Produktion, Osnabrück, CD 2 cpo 999 058-2 [Audio-CD booklet]

• Hierholzer K, Perschel FH (1991) Ormoni e Rene (Hormones and Kidney) In: Nefrologia Pediatrica. De Santo NG, Capasso G (eds.). Editoriale Bios. Chapter 3: 49-77 [Italian textbook of Pediatric Nephrology]

• Hierholzer K, Ritz E (1991) Nieren und ableitende Harnwege. In: Pathophysiologie des Menschen. VCH Verlagsgesellschaft. Herausgeber: Hierholzer K und Schmidt RF, edition medizin VCH, Weinheim, Kap.9, pp 9.1-9.30 [textbook of Pathophysiology]

• Hierholzer K, Schmidt RF (editors) (1991) Pathophysiologie des Menschen. VCH Verlagsgesellschaft, edition medizin VCH, Weinheim [Textbook of Pathophysiology]

• Kreusel KM, Fromm M, Schulzke JD, Hegel U (1991) Cl^- secretion in epithelial monolayers of mucus-forming human colon cells (HT-29/B6). Am. J. Physiol. 261: C574-C582. [PubMed] [PDF]

• Lepple-Wienhues A, Stahl F, Wiederholt M (1991) Differential smooth muscle-like contractile properties of trabecular meshwork and ciliary muscle. Exp. Eye Res. 53: 33-38 [PubMed]

• Lepple-Wienhues A, Stahl F, Willner U, Schäfer R, Wiederholt M (1991) Endothelin-evoked contractions in bovine ciliary muscle and trabecular meshwork: interaction with calcium, nifedipine and nickel. Curr. Eye Res. 10: 983-989 [PubMed]

• Perschel FH, Bühler H, Hierholzer K (1991) Bile acids and their amidates inhibit 11b-hydroxysteroid dehydrogenase obtained from rat kidney. Pflügers Arch. 418: 538-543 [PubMed] [PDF]

• Roslyn JJ, Abedin MZ, Saunders KD, Cates JA, Strichartz SD, Alperin M, Fromm M, Palant CE (1991) Uncoupled basal sodium absorption and chloride secretion in prairie dog gallbladder. Comp. Biochem. Physiol. A 100: 335-341. [PubMed]

• Strauss O, Wiederholt M (1991) Transepithelial resistance of ciliary epithelial cells in culture: Functional modification by protamine and extracellular calcium. Comp. Biochem. Physiol. A 100: 987-993, 1991 [PubMed]

• Stahl F, Lepple-Wienhues A, Kuppinger M, Schneider U, Wiederholt M (1991) Measurements of intracellular calcium and contractility in human ciliary muscle. Pflügers Arch. 418: 531-537 [PubMed] [PDF]

• Ullrich KJ, Rumrich G, Papavassiliou F, Hierholzer K (1991) Contraluminal p-aminohippurate transport in the proximal tubule of the rat kidney. VIII. Transport of Corticosteroids. Pflügers Arch. 418: 371-382 [PubMed] [PDF]

• Wiederholt M, Helbig H, Korbmacher C (1991) Ion transport across the ciliary epithelium: lessons from cultured cells and proposed role of carbonic anhydrase. In: Carbonic Anhydrase. Eds. F. Botre, G. Gross, B.T. Storey. VCH, Weinheim, New York, Basel, Cambridge, pp. 232-244

1990

• Ebel H (1990) Na⁺-dependent D-glucose transport in Mg-deficient rat renal brush border membranes. Magnesium Res. 3: 51-52.

• Ebel H (1990) Intestinal magnesium absorption. In: Metal ions in biological systems, Vol. 26, Compendium on magnesium and its role in biology, nutrition, and physiology, Ed. Sigel, H., pp. 227-248, Marcel Dekker Inc., New York

• Fromm M, Schulzke JD, Hegel U (1990) Aldosterone low dose, short term action in adrenalectomized glucocorticoid-substituted rats: Na, K, Cl, HCO₃, osmolyte, and water transport in proximal and rectal colon. Pflügers Arch. 416: 573-579. [PubMed] [PDF]

• Fromm M, Tykocinski M, Schulzke JD, Hegel U, Bentzel CJ (1990) pH-dependence of protamine action on apical membrane permeability in Necturus gallbladder epithelium. Biochim. Biophys. Acta 1027: 179-184. [PubMed] [PDF]

• Günther T, Ebel H (1990) Membrane transport of magnesium. In: Metal ions in biological systems, Vol. 26, Compendium on magnesium and its role in biology, nutrition, and physiology, Ed. Sigel H., pp. 215-225, Marcel Dekker Inc., New York. [Review article]

• Hegel U, Fromm M (1990) Electrical measurements in large intestine (including colon, rectum, caecum). Methods Enzymol. 192: 459-484. [PubMed reference] [PDF]

• Helbig H, Korbmacher C, Wiederholt M (1990) [Mechanism of ascorbic acid transport in the aqueous humor]. Fortschr. Ophthalmol. 87: 421-424 [PubMed]

• Hierholzer K, Siebe H, Fromm M (1990) Inhibition of 11-b-hydroxysteroid dehydrogenase and its effect on epithelial sodium transport. Kidney Int. 38: 673-678 [Abstract+References] [PDF]

• Hierholzer K (Sprecher), Winau R, Fischer W (1990) Bericht der Arbeitsgruppe "Exodus von Wissenschaften aus Berlin". In: Jahrbuch, Akademie der Wissenschaften zu Berlin 1989, de Gruyter Verlag Berlin New York, pp 283-293

• Korbmacher C, Helbig H, Coroneo MT, Erickson-Lamy KA, Stiemer B, Tamm E, Lütjen-Drecoll E, Wiederholt M (1990) Membrane voltage recordings in a primary cell line derived from human ciliary muscle. Invest. Ophthalmol. Vis. Sci. 31: 2420-2430 [PubMed]

• Pahlitzsch T, Wyrobisch W, Kämpe C, Wiederholt M (1990) [Therapy of the ocular form of Behcet disease with cyclosporin A]. Klin. Monatsbl. Augenheilk. 196: 466-469 [PubMed]

• Schulzke JD, Fromm M, von Hippel C, Sandforth W, Menge H, Bentzel CJ, Riecken EO (1990) Adaptation of epithelial ion transport in the short bowel syndrome. Digestion 46: 467-471 [PubMed]

• Schulzke JD, Fromm M, Riecken EO, Reutter W (1990) Enkephalin affects ion transport via the enteric nervous system in guinea pig ileum. Eur. J. Clin. Invest. 20: 182-191 [PubMed]

• Schulzke JD, Fromm M, Zeitz M, Menge H, Riecken EO, Bentzel CJ (1990) Tight junction regulation during impaired ion transport in blind loops of rat jejunum. Res. Exp. Med. 190: 59-68 [PubMed]

• Wiederholt M, Jentsch TJ (1990) Cell culture of bovine corneal endothelial cells and its application to transport studies. Methods Enzymol. 192: 571-582 [PubMed summary]

• Wiederholt M, Wiek J, Hansen LL (1990) Hämodilution bei Durchblutungsstörungen der Retina. Folia Ophthalmol. 15: 113-116

• Wiederholt M, Zadunaisky JA (1990) Electrolyte transport across the ciliary epithelium of the shark. In: Animal Nutrition and Transport Processes. 2. Transport, Respiration and Excretion: Comparative and Environmental Aspects, Eds. J.-P.Truchot and B. Lahlou, Comp. Physiol. Basel, Karger, vol 6, pp 171-184

• Wiek J, Krause M, Wiederholt M, Hansen LL (1990) [Hemorheologic parameters in patients with giant cell arteritis before and after treatment with steroids]. Fortschr. Ophthalmol. 87: 671-674 [PubMed]

• Wiek J, Schade M, Wiederholt M, Arntz HR, Hansen LL (1990) Haemorheological changes in patients with retinal vein occlusion after isovolaemic haemodilution. Brit. J. Ophthalmol. 74: 665-669 [PubMed]

1989

• Castello R, Schwarting R, Müller C, Hierholzer K, Lichtenstein I (1989) Immunohistochemical localization of 11-hydroxysteroid dehydrogenase in rat kidney with a monoclonal antibody. Renal Physiol. Biochem. 12: 320-327 [PubMed]

• Coroneo MT, Helbig H, Korbmacher C, Wiederholt M (1989) Effect of hypotonic media on the membrane voltage of cultured bovine corneal endothelial cells. Curr. Eye Res. 8: 891-899 [PubMed]

• Flügel C, Lütjen-Drecoll E, Zadunaisk JA, Wiederholt M (1989) Regional differences in the morphology and enzyme distribution of the spiny dogfish (Squalus acanthias) ciliary epithelium. Exp. Eye Res. 49: 1097-1114 [PubMed]

• Hansen LL, Wiek J, Schade M, Müller-Stolzenburg N, Wiederholt M (1989) Effect and compatibility of isovolaemic haemodilution in the treatment of ischaemic and non-ischaemic central retinal vein occlusion. Ophthalmologica 199: 90-99 [PubMed]

• Hansen LL, Wiek J, Wiederholt M (1989) A randomised prospective study of treatment of non-ischaemic central retinal vein occlusion by isovolaemic haemodilution. Br. J. Ophthalmol. 73: 895-899 [PubMed]

• Helbig H, Korbmacher C, Erb C, Nawrath M, Knuuttila KG, Wistrand P, Wiederholt M (1989) Coupling of ²²Na and ³⁶Cl uptake in cultured pigmented ciliary epithelial cells: a proposed role for the isoenzymes of carbonic anhydrase. Curr. Eye Res. 8: 1111-1119 [PubMed]

• Helbig H, Korbmacher C, Erb C, Nawrath M, Knuuttila KG, Wistrand P, Wiederholt M (1989) [Carbonic anhydrase and its function in ion transport in cultivated pigmented ciliary body epithelial cells]. Fortschr. Ophthalmol. 86: 474-477 [PubMed]

• Helbig H, Korbmacher C, Nawrath M, Erb C, Wiederholt M (1989) Sodium bicarbonate cotransport in cultured pigmented ciliary epithelial cells. Curr. Eye Res. 8: 595-598 [PubMed]

• Helbig H, Korbmacher C, Wohlfarth J, Berweck S, Kuhner D, Wiederholt M (1989) Electrogenic Na⁺-ascorbate cotransport in cultured bovine pigmented ciliary epithelial cells. Am. J. Physiol. 256: C44-C49 [PubMed] [PDF]

• Helbig H, Korbmacher C, Stumpff F, Coca-Prados M, Wiederholt M (1989) Role of HCO₃^- in regulation of cytoplasmic pH in ciliary epithelial cells. Am. J. Physiol. 257: C696-C705 [PubMed] [PDF]

• Helbig H, Korbmacher C, Wohlfarth J, Coca-Prados M, Wiederholt M (1989) Intracellular voltage recordings in bovine non-pigmented ciliary epithelial cells in primary culture. Curr. Eye Res. 8: 793-800 [PubMed]

• Helbig H, Korbmacher C, Wohlfarth J, Coca-Prados M, Wiederholt M (1989) Electrical membrane properties of a cell clone derived from human nonpigmented ciliary epithelium. Invest. Ophthalmol. Vis. Sci. 30: 882-889 [PubMed]

• Helbig H, Korbmacher C, Wohlfarth J, Coroneo MT, Lindschau C, Quass P, Haller H, Coca-Prados M, Wiederholt M (1989) Effect of acetylcholine on membrane potential of cultured human nonpigmented ciliary epithelial cells. Invest. Ophthalmol. Vis. Sci. 30: 890-896 [PubMed]

• Hierholzer K (Sprecher), Winau R, Hubenstorf M (1989) Bericht der Arbeitsgruppe "Exodus von Wissenschaften aus Berlin". In: Jahrbuch, Akademie der Wissenschaften zu Berlin 1988, de Gruyter-Verlag Berlin New York, pp 432-446

• Korbmacher C, Helbig H, Forster C, Wiederholt M (1989) [Measuring intracellular pH in cultivated corneal epithelial cells]. Fortschr. Ophthalmol. 86: 279-282 [PubMed]

• Korbmacher C, Helbig H, Haller H, Erickson-Lamy KA, Wiederholt M (1989) Endothelin depolarizes membrane voltage and increases intracellular calcium concentration in human ciliary muscle cells. Biochem. Biophys. Res. Commun. 164: 1031-1039 [PubMed]

• Korbmacher C, Helbig H, Stahl F, Coroneo M, Haller H, Lindschau C, Quass P, Wiederholt M (1989) Continuous membrane voltage recordings in A10 vascular smooth muscle cells: effect of AVP. Am. J. Physiol. 257: C323-C332 [PubMed] [PDF]

• Korbmacher C, Schulz W, König M, Siebe H, Lichtenstein I, Hierholzer K (1989) Renal epithelial cell lines (BSC-1, MDCK, LLC-PK1) express 11b-hydroxysteroid dehydrogenase activity. Biochim. Biophys. Acta 1010: 311-317 [PubMed]

• Schulz W, Lichtenstein I, Siebe H, Hierholzer K (1989) Isoelectric focusing analysis of detergent extracted renal 11b-hydroxysteroid dehydrogenase. J. Steroid Biochem. 32: 581-590  [PubMed]

• Schulzke JD, Fromm M, Hegel U, Riecken EO (1989) Ion transport and enteric nervous system (ENS) in rat rectal colon: Mechanical stretch causes electrogenic Cl-secretion via Plexus Meissner and amiloride-sensitive electrogenic Na-absorption is not affected by intramural neurons. Pflügers Arch. 414: 216-221. [PubMed] [PDF]

• Wiederholt M, Flügel C, Lütjen-Drecoll E, Zadunaisky JA (1989) Mechanically stripped pigmented and non-pigmented epithelium of the shark ciliary body: morphology and transepithelial electrical properties. Exp. Eye Res. 49: 1031-1043 [PubMed]

1988

• l'Allemand D, Siebe H, Tsiakiras D, Hoyer GA, Vecsei P, Hierholzer K (1988) Aldosterone metabolism in rat renal tissue in vitro. Formation of lipid soluble metabolites. Pflügers Arch. 411: 529-539 [PubMed]

• Helbig H, Korbmacher C, Berweck S, Kuhner D, Wiederholt M (1988) Kinetic properties of Na⁺/H⁺ exchange in cultured bovine pigmented ciliary epithelial cells. Pflügers Arch. 412: 80-85 [PubMed]

• Helbig H, Korbmacher C, Berweck S, Kuhner D, Wiederholt M (1988) [Culture of ciliary body epithelia and studies of ion transport]. Fortschr. Ophthalmol. 85: 42-45 [PubMed reference]

• Helbig H, Korbmacher C, Kuhner D, Berweck S, Wiederholt M (1988) Characterization of Cl^-/HCO₃^- exchange in cultured bovine pigmented ciliary epithelium. Exp. Eye Res. 47: 515-523 [PubMed]

• Helbig H, Korbmacher C, Stumpff F, Coca-Prados M, Wiederholt M (1988) Na⁺/H⁺ exchange regulates intracellular pH in a cell clone derived from bovine pigmented ciliary epithelium. J. Cell Physiol. 137: 384-389 [PubMed]

• Hierholzer K (1988) Arbeitsgruppe "Exodus von Wissenschaften aus Berlin" Bericht. In: Jahrbuch, Akademie der Wissenschaften zu Berlin, 1987, de Gruter Verlag Berlin New York, pp 110-113

• Hoffmann F, von Keyserlingk HJ, Wiederholt M (1988) [Significance of transplantation antigens in keratoplasty]. Fortschr. Ophthalmol. 85: 186-189 [PubMed reference]

• Korbmacher C, Helbig H, Forster C, Wiederholt M (1988) Characterization of Na⁺/H⁺ exchange in a rabbit corneal epithelial cell line (SIRC). Biochim. Biophys. Acta 943: 405-410 [PubMed]

• Jentsch TJ, Korbmacher C, Janicke I, Fischer DG, Stahl F, Helbig H, Hollwede H, Cragoe EJ Jr, Keller SK, Wiederholt M (1988) Regulation of cytoplasmic pH of cultured bovine corneal endothelial cells in the absence and presence of bicarbonate. J. Membr. Biol. 103: 29-40 [PubMed]

• Keller SK, Jentsch TJ, Janicke I, Wiederholt M (1988) Regulation of intracellular pH in cultured bovine retinal pigment epithelial cells. Pflügers Arch. 411: 47-52 [PubMed]

• Korbmacher C, Helbig H, Stahl F, Wiederholt M (1988) Evidence for Na/H exchange and Cl/HCO₃ exchange in A10 vascular smooth muscle cells. Pflügers Arch. 412: 29-36 [PubMed]

• Korbmacher C, Helbig H, Forster C, Wiederholt M (1988) Evidence for Na⁺/H⁺ exchange and pH sensitive membrane voltage in cultured bovine corneal epithelial cells. Curr. Eye Res. 7: 619-626 [PubMed]

1987

• Bentzel CJ, Fromm M, Palant CE, Hegel U (1987) Protamine alters structure and conductance of Necturus gallbladder tight junctions without major electrical effects on the apical cell membrane. J. Membr. Biol. 95: 9-20. [PubMed] [PDF]

• Fromm M, Hegel U (1987) Net ion fluxes and zero flux limiting concentrations in rat upper colon and rectum during anaesthesia-induced aldosterone liberation. Pflügers Arch. 408: 185-193. [PubMed] [PDF]

• Helbig H, Korbmacher C, Wiederholt M (1987) K⁺-conductance and electrogenic Na⁺/K⁺ transport of cultured bovine pigmented ciliary epithelium. J. Membr. Biol. 99: 173-186 [PubMed]

• Hierholzer K, Fromm M (1987) Wasser- und Elektrolythaushalt; Physiologie der Niere. In: Lehrbuch der Veterinär-Physiologie (Scheunert/Trautmann), G. Wittke, editor, 7^th edn., Paul Parey, Berlin, chapter 8, pp 359-436. [Textbook of Veterinary Physiology]

• von Keyserlingk H, Offermann G, Wiederholt M, Hoffmann F (1987) The importance of HLA-DR matching in corneal transplant recipients treated with cyclosporine A. Transplant. Proc. 19: 2576-2578 [PubMed reference]

• Kobayashi N, Schulz W, Hierholzer K (1987) Corticosteroid metabolism in rat kidney in vitro. IV. Subcellular, sites of 11-hydroxysteroid dehydrogenase activity. Pflügers Arch. 408: 46-53 [PubMed]

• Schulzke JD, Fromm M, Bentzel CJ, Menge H, Riecken EO (1987) Adaptation of the jejunal mucosa in the experimental blind loop syndrome: changes in paracellular conductance and tight junction structure. Gut 28: 159-164 [PubMed] [PDF]

• Schulzke JD, Fromm M, Menge H, Riecken EO (1987) Impaired intestinal sodium and chloride transport in the blind loop syndrome of the rat. Gastroenterology 92: 693-698. [PubMed] [PDF]

• Wiederholt M (1987) [Electrolyte transport in the epithelium and endothelium of the cornea]. Fortschr. Ophthalmol. 84: 301-306. Review [PubMed reference]

• Wiederholt M, Zadunaisky JA (1987) Effects of ouabain and furosemide on transepithelial electrical parameters of the isolated shark ciliary epithelium. Invest. Ophthalmol. Vis. Sci. 28: 1353-1356 [PubMed]

1986

• Fromm M, Palant CE, Bentzel CJ, Hegel U (1985) Protamine reversibly decreases paracellular cation permeability in Necturus gallbladder. J. Membr. Biol. 87: 141-150. [PubMed] [PDF]

• Hoffmann F, von Keyserlingk HJ, Wiederholt M (1986) Importance of HLA DR matching for corneal transplantation in high-risk cases. Cornea 5: 139-143 [PubMed reference]

• Hierholzer K (1986) Diuretika als spezifische Elektrolyttransport-Inhibitoren (SETI). In: Diuretika. H. Knauf/E. Mutschler (Hrsg.) Urban & Schwarzenberg, München, pp 169-172

• Hoffmann F, von Keyserlingk HJ, Wiederholt M (1986) [Significance of HLA typing in corneal transplants with unfavorable prognosis in cyclosporin A therapy]. Fortschr. Ophthalmol. 83: 542-546 [PubMed reference]

• Hoffmann F, Wiederholt M (1986) Topical cyclosporin A in the treatment of corneal graft reaction. Cornea. 5: 129 [PubMed reference]

• Hoffmann F, Wiederholt M, Kossendrup D (1986) [Effect of cyclosporin A, dexamethasone and various preservatives on epithelial wound healing in the denervated guinea pig cornea]. Klin. Monatsbl. Augenheilkd. 189: 30-33 [PubMed]

• Jentsch TJ, Janicke I, Sorgenfrei D, Keller SK, Wiederholt M (1986) The regulation of intracellular pH in monkey kidney epithelial cells (BSC-1). Roles of Na⁺/H⁺ antiport, Na⁺-HCO₃(^-)-(NaCO₃^-) symport, and Cl^-/HCO₃^- exchange. J. Biol. Chem. 261: 12120-12127 [PubMed] [PDF]

• Jentsch TJ, Matthes H, Keller SK, Wiederholt M (1986) Electrical properties of sodium bicarbonate symport in kidney epithelial cells (BSC-1). Am. J. Physiol. 251: F954-F968 [PubMed] [PDF]

• Jentsch TJ, Schwartz P, Schill BS, Langner B, Lepple AP, Keller SK, Wiederholt M (1986) Kinetic properties of the sodium bicarbonate (carbonate) symport in monkey kidney epithelial cells (BSC-1). Interactions between Na⁺, HCO₃^-, and pH. J. Biol. Chem. 261: 10673-10679 [PubMed] [PDF]

• Keller SK, Jentsch TJ, Koch M, Wiederholt M (1986) Interactions of pH and K⁺ conductance in cultured bovine retinal pigment epithelial cells. Am. J. Physiol. 250: C124-C137 [PubMed] [PDF]

• Schulzke JD, Fromm M, Hegel U (1986) Epithelial and subepithelial resistance of rat large intestine: Segmental differences, effect of stripping, time course, and action of aldosterone. Pflügers Arch. 407: 632-637 [PubMed] [PDF]

• Schulzke JD, Fromm M, Menge H, Reutter W, Riecken EO (1986) Die neurogene Steuerung der Chlorid-Sekretion der Ileumschleimhaut [Neurogenic control of chloride secretion of the ileal mucosa]. Z. Gastroent. 24: 62-69 [PubMed reference]

• Wiederholt M, Kampe C, Hansen LL, Hövener G (1986) [Treatment of posterior uveitis with cyclosporin or prednisolone - one-year report of a randomized prospective study]. Fortschr. Ophthalmol. 83: 348-352 [PubMed reference]

• Wiederholt M, Kossendrup D, Schulz W, Hoffmann F (1986) Pharmacokinetic of topical cyclosporin A in the rabbit eye. Invest. Ophthalmol. Vis. Sci. 27: 519-524 [PubMed]

• Wiederholt M, Zadunaisky JA (1986) Membrane potentials and intracellular chloride activity in the ciliary body of the shark. Pflügers Arch. 407 Suppl 2: S112-S115 [PubMed]

• Wiederholt M, Zadunaisky JA (1986) Effect of calcium antagonist compound nisoldipine on transepithelial electrical parameters in the isolated frog cornea. J. Ocul. Pharmacol. 2: 159-164 [PubMed]

1985

• Ebel H, Ruf W (1985) Anion sensitive ATPase in human cornea. Curr. Eye Res. 4: 393-397. [PubMed]

• Fromm M, Palant CE, Bentzel CJ, Hegel U (1985) Protamine reversibly decreases paracellular cation permeability in Necturus gallbladder. J. Membr. Biol. 87: 141-150. [PubMed] [PDF]

• Fromm M, Schulzke JD, Hegel U (1985) Epithelial and subepithelial contributions to transmural electrical resistance of intact rat jejunum, in vitro. Pflügers Arch. 405: 400-402. [PubMed] [PDF]

• Groeben C, Hierholzer K (1985) Emil du Bois-Reymond - Anton Dohrn, Briefwechsel. Springer, Berlin [Book]

• Hansen LL, Danisevskis P, Arntz HR, Hovener G, Wiederholt M (1985) A randomised prospective study on treatment of central retinal vein occlusion by isovolaemic haemodilution and photocoagulation. Br. J. Ophthalmol. 69: 108-116 [PubMed]

• Hansen LL, Hövener G, Mercks C, Tavakolian U, Wiederholt M (1985) [Isovolemic hemodilution in patients with retinal branch vein occlusion]. Fortschr. Ophthalmol. 82: 290-292 [PubMed reference]

• Hierholzer K (1985) Sodium reabsorption in the distal tubular system. In: The Kidney: Physiology and Pathophysiology, edited by Seldin DW and Giebisch G, Raven Press, New York, pp 1063-1096 [Handbook article]

• Hoffmann F, Wiederholt M (1985) Local treatment of necrotizing scleritis with cyclosporin A. Cornea 4: 3-7 [PubMed]

• Hoffmann F, Wiederholt M (1985) [Local treatment of corneal transplants in the human with cyclosporin A]. Klin. Monatsbl. Augenheilkd. 187: 92-96 [PubMed]

• Jentsch TJ, Keller SK, Wiederholt M (1985) Ion transport mechanisms in cultured bovine corneal endothelial cells. Curr. Eye Res. 4: 361-369 [PubMed]

• Jentsch TJ, Matthes H, Keller SK, Wiederholt M (1985) Anion dependence of electrical effects of bicarbonate and sodium on cultured bovine corneal endothelial cells. Pflügers Arch. 403: 175-185 [PubMed] [PDF]

• Jentsch TJ, Schill BS, Schwartz P, Matthes H, Keller SK, Wiederholt M (1985) Kidney epithelial cells of monkey origin (BSC-1) express a sodium bicarbonate cotransport. Characterization by ²²Na⁺ flux measurements. J. Biol. Chem. 260: 15554-15560 [PubMed] [PDF]

• Jentsch TJ, Stahlknecht TR, Hollwede H, Fischer DG, Keller SK, Wiederholt M (1985) A bicarbonate-dependent process inhibitable by disulfonic stilbenes and a Na⁺/H⁺ exchange mediate ²²Na⁺ uptake into cultured bovine corneal endothelium. J. Biol. Chem. 260: 795-801 [PubMed] [PDF]

• Jentsch TJ, von der Haar B, Keller SK, Wiederholt M (1985) Response of the intracellular potentials of cultured bovine lens cells to ions and inhibitors. Exp. Eye Res. 41: 131-144 [PubMed]

• Kana JS, Wiederholt M (1985) Effect of corticosteroids on electrolyte transport of the isolated human and rabbit lens. Curr. Eye Res. 4: 461-465 [PubMed]

• Kossendrup D, Wiederholt M, Hoffmann F (1985) Influence of cyclosporin A, dexamethasone, and benzalkonium chloride (BAK) on corneal epithelial wound healing in the rabbit and guinea pig eye. Cornea 4: 177-181 [PubMed]

• Wiederholt M, Jentsch TJ, Keller SK (1985) Electrogenic sodium-bicarbonate symport in cultured corneal endothelial cells. Pflügers Arch. 405 Suppl 1: S167-S171 [PubMed] [PDF]

1984

• Cohen B, Giebisch G, Hansen LL, Teuscher U, Wiederholt M (1984) Relationship between peritubular membrane potential and net fluid reabsorption in the distal renal tubule of Amphiuma. J. Physiol. (Lond). 348: 115-134 [PubMed] [PDF]

• Hierholzer K, Schöneshöfer M, Siebe H, Tsiakiras D, Weskamp P (1984) Corticosteroid metabolism in isolated rat kidney in vitro. I. Formation of lipid soluble metabolites from corticosterone (B) in renal tissue from male rats. Pflügers Arch. 400: 363-371 [PubMed] [PDF]

• Hoyer GA, Tsiakiras D, Siebe H, Hierholzer K (1984) Corticosteroid metabolism in isolated rat kidney in vitro. III. Structure analysis of lipid soluble metabolites of corticosterone. Pflügers Arch. 400: 377-380 [PubMed] [PDF]

• Jentsch TJ, Keller SK, Koch M, Wiederholt M (1984) Evidence for coupled transport of bicarbonate and sodium in cultured bovine corneal endothelial cells. J. Membr. Biol. 81: 189-204 [PubMed] [PDF]

• Jentsch TJ, Koch M, Bleckmann H, Wiederholt M (1984) Effect of bicarbonate, pH, methazolamide and stilbenes on the intracellular potentials of cultured bovine corneal endothelial cells. J. Membr. Biol. 78: 103-117 [PubMed] [PDF]

• Kana JS, Wiederholt M (1984) Corticosteroids and the active ion transport of the isolated human lens. Ann. Ophthalmol. 16: 1034-1039 [PubMed]

• Siebe H, Tsiakiras D, Hierholzer K, with techn. assistance of Lichtenstein I (1984) Corticosteroid metabolism in isolated rat kidney in vitro. II. Sex dependency of metabolism and formation of 11-dehydro-corticosterone. Pflügers Arch. 400: 372-376 [PubMed] [PDF]

• Wiederholt M, Hampel J, Belkien L, Oelkers W (1984) Aldosterone secretion, measurements of membrane potential and intracellular potassium activity in the isolated adrenal zone glomerulosa. FEBS Lett. 174: 211-214 [PubMed] [PDF]

• Wiederholt M, Keller S, Krolik A, Jentsch TJ (1984) The calcium antagonist nisoldipine stimulates the electrolyte transport of the isolated frog skin. Biochem. Pharmacol. 33: 2926-2928 [PubMed reference]

• Wiederholt M, Zadunaisky JA (1984) Decrease of intracellular chloride activity by furosemide in frog retinal pigment epithelium. Curr. Eye Res. 3: 673-675 [PubMed]

1983

• Danisevskis P, Hansen LL, Arntz HR, Hovener G, Wiederholt M (1983) [Treatment of central retinal vein occlusion by isovolemic hemodilution and photocoagulation]. Fortschr. Ophthalmol. 80: 173-175 [PubMed reference]

• Ebel H, Günther T (1983) Role of magnesium in cardiac disease. J. Clin. Chem. Clin. Biochem. 21: 249-265 [PubMed] [PDF]

• Fromm M, Oelkers W, Hegel U (1983) Time course of aldosterone and corticosterone plasma levels in rats during general anaesthesia and abdominal surgery. Pflügers Arch. 399: 249-254. [PubMed] [PDF]

• Vormann J, Förster R, Günther T, Ebel H (1983) Lipolysin-induced magnesium uptake into fat cells. Magnesium-Bull. 5: 29-41.

• Wiederholt M, Schmidt DK, Eggebrecht R, Zimmermann J, Fischer FH (1983) Adrenergic regulation of sodium and chloride transport in the isolated cornea of rabbit and man. Graefes Arch. Clin. Exp. Ophthalmol. 220: 240-244 [PubMed] [PDF]

 1982

• Fischer FH, Wiederholt M (1982) Human precorneal tear film pH measured by microelectrodes. Graefes Arch. Clin. Exp. Ophthalmol. 218: 168-170 [PubMed] [PDF]

• Hierholzer K (1982) Value and necessity of animal research in nephrolgoy. Exp. Biol. Med. 7: 88-101

• Hierholzer K, Lichtenstein I, Siebe H, Tsiakiras D, Witt I (1982) Renal metabolism of corticosteroid hormones. Klin. Wschr. 60: 1127-1135 [PubMed] [PDF]

• Kana JS, Hoffmann F, Buchen R, Krolik A, Wiederholt M (1982) Rabbit corneal allograft survival following topical administration of cyclosporin A. Invest. Ophthalmol. Vis. Sci. 22: 686-690 [PubMed]

• Kana JS, Hoffmann F, Buchen R, Krolik A, Wiederholt M (1982) [Effect of local administration of cyclosporin A on corneal graft survival in the rabbit]. Fortschr. Ophthalmol. 79: 132-134 [PubMed reference]

• Welsh MJ, Smith PL, Fromm M, Frizzell RA (1982) Crypts are the site of intestinal fluid and electrolyte secretion. Science 218: 1219-1221. [PubMed] [PDF] (see also Köckerling & Fromm, 1993)

1981

• Fromm M, Schultz SG (1981) Some properties of KCl-filled microelectrodes: Correlation of potassium "leakage" with tip resistance. J. Membr. Biol. 62: 239-244. [PubMed] [PDF]

• Fromm M, Schultz SG (1981) Potassium transport across rabbit descending colon in vitro: Evidence for single-file diffusion through a paracellular pathway. J. Membr. Biol. 63: 93-98. [PubMed] [PDF]

• Hansen LL, Schilling AR, Wiederholt M (1981) Effect of calcium, furosemide and chlorothiazide on net volume reabsorption and basolateral membrane potential of the distal tubule. Pflügers Arch. 389: 121-126 [PubMed]

• Platsch KD, Wiederholt M (1981) Effect of ion substitution and ouabain on short circuit current in the isolated human and rabbit lens. Exp. Eye Res. 32: 615-625 [PubMed reference]

• Platsch KD, Wiederholt M (1981) Intracellular potassium activity and cell membrane potential of the isolated human and rabbit lens. Exp. Eye Res. 33: 467-478 [PubMed reference]

• Wiederholt M (1981) Hemodilution in retinal hypoperfusion. Bibl. Haematol. 47: 185-191 [PubMed reference]

• Wiederholt M (1981) [Hemodilution in ocular circulation disorders]. Verh. Dtsch. Ges. Inn. Med. 87: 1354-1357 [PubMed reference]

1980

• Ebel H, Günther T (1980) Magnesium metabolism: a review. J. Clin. Chem. Clin. Biochem. 18: 257-270. [PubMed]

• Ebel H, Günther T (1980) [Magnesium - the 2^nd most abundant intracellular cation]. Med. Klin. 75: 257-263 [PubMed reference]

• Ebel H, Gebhard A (1980) Protein metabolism of renal basolateral membranes in rat. Int. J. Biochem. 12: 315-318 [PubMed reference]

• Fromm M, Weskamp P, Hegel U (1980) Versatile piezoelectric driver for cell puncture. Pflügers Arch. 384: 69-73 [PubMed] [PDF]

• Gutsche HU, Müller-Suur R, Hegel U, Hierholzer K (1980) Electrical conductivity of tubular fluid of the rat nephron. Pflügers Arch. 383: 113-121 [PubMed reference] [PDF]

• Gutsche HU, Müller-Suur R, Samwer KF, Beer G, Hierholzer K (1980) Tubuloglomerular feedback control in kidneys of adrenalectomized rats. Pflügers Arch. 386: 11-19 [PubMed reference] [PDF]

• Hierholzer K, Kawamura S, Seldin DW, Kokko JP, Jacobson HR (1980) Reflection coefficients of various substrates across superficial and juxtameduallary proximal convoluted segments of rabbit nephrons. Mineral Electrolyte Metab. 3: 172-180

• Wiederholt M (1980) Physiology of epithelial transport in the human eye. Klin. Wochenschr. 58: 975-984. (Review) [PubMed reference] [PDF]

• Wiederholt M, Danisevskis P, Hansen LL, Lichey HJ, Platsch KD (1980) The effects of extracellular potassium, ouabain, and prostaglandins on intracellular potassium activity in sheep cardica Purkinje fibers. Pflügers Arch. 388: 169-175 [PubMed] [PDF]

• Wiederholt M, Hansen LL (1980) Amphiuma kidney as a model for distal tubular transport studies. Contrib. Nephrol. 19: 28-32 [PubMed reference]

• Wiederholt M, Leonhardt H, Schmid-Schonbein H, Hager H (1980) [Treatment of central retinal venous and arterial occlusion by isovolemic hemodilution]. Klin. Monatsbl. Augenheilkd. 177: 157-164 [PubMed]

1979

• Hansen LL, Koch M, Platsch KD, Wiederholt M (1979) Intracellular potassium activity of isolated human and rabbit corneal epithelium. Exp. Eye Res. 29: 367-378 [PubMed reference]

• Wieland R, Wiederholt M, Hager H (1979) [Clinical and experimental evaluation of hydrophilic contact lenses for continuous-wear]. Klin. Monatsbl. Augenheilkd. 175: 664-966 [PubMed]

• Wiederholt M, Koch M (1979) Effect of intraocular irrigating solutions on intracellular membrane potentials and swelling rate of isolated human and rabbit cornea. Invest. Ophthalmol. Vis. Sci. 18: 313-317 [PubMed]

1978

• Fischer FH, Schmitz L, Hoff W, Schartl S, Liegl O, Wiederholt M (1978) Sodium and chloride transport in the isolated human cornea. Pflügers Arch. 373: 179-188 [PubMed] [PDF]

• Fischer FH, Wiederholt M (1978) The pH dependency of sodium and chloride transport in the isolated human cornea. Invest. Ophthalmol. Vis. Sci. 17: 810-813 [PubMed]

• Fromm M, Hegel U (1978) Segmental heterogeneity of epithelial transport in rat large intestine. Pflügers Arch. 378: 71-83 [PubMed] [PDF] (congruent to doctoral thesis of MF)

• Hierholzer K (1978) Modes of action of diuretics. Contrib. Nephrol. 14: 111-117 [PubMed reference]

• Wiederholt M, Koch M (1978) Intracellular potentials of isolated rabbit and human corneal epithelium. Exp. Eye Res. 26: 629-640 [PubMed reference]

• Wiederholt M, Koch M (1978) Intracellular potentials of isolated rabbit and human corneal endothelium. Exp. Eye Res. 27: 511-518 [PubMed reference]

 1977

• Ebel H, Aulbert E, Averdunk R (1977) Inhibition of (Na⁺K⁺)-ATPase and cation transport by an antibody against renal plasma membranes. Curr. Probl. Clin. Biochem. 8: 150-158. [PubMed]

• Ebel H, Aulbert E, Averdunk R (1977) Inhibition of renal (Na⁺K⁺)-ATPase and cation transport by an antibody against NaI extracted kidney plasma membranes. Pflügers Arch. 370: 269-276. [PubMed reference] [PDF]

• Hierholzer K (1977) Das Renin-Angiotensin-Aldosteronsystem. In: Gauer, Kramer, Jung: "Physiologie des Menschen", Bd.20: Endokrinologie III, pp 219-261, Urban & Schwarzenberg, München [Textbook of Physiology]

• Hierholzer K (1977) Prostaglandine. In: Gauer, Kramer, Jung: "Physiologie des Menschen", Bd.20: Endokrinologie III, pp 263-282, Urban & Schwarzenberg, München (1977) [Textbook of Physiology]

• Hierholzer K (1977) Die Nebennierenrinde. In: Gauer, Kramer, Jung: "Physiologie des Menschen", Bd.19: Endokrinologie II, pp 1-63, Urban & Schwarzenberg, München [Textbook of Physiology]

• Hierholzer K (1977) Die Adenohypophyse. In: Gauer, Kramer, Jung: "Physiologie des Menschen", Bd. 18: Endokrinologie I, pp 87-164, Urban & Schwarzenberg, München [Textbook of Physiology]

• Hierholzer K (1977) Das Hypothalamus-Neurohypophysen-System. In: Gauer, Kramer, Jung: "Physiologie des Menschen", Bd. 18: Endokrinologie I, pp 165-204, Urban & Schwarzenberg, München [Textbook of Physiology]

• Hierholzer K (1977) Der Hypothalamus als endokrines Organ. In: Gauer, Kramer, Jung "Physiologie des Menschen", Bd. 18: Endokrinologie I, pp 57-85, Urban & Schwarzenberg, München [Textbook of Physiology]

• Hierholzer K, Kleinschmidt J (1977) Renale Wirkungen von Diuretika. Berliner Seminar 1, Physiologische und pharmakologische Grundlagen der Therapie (Herzglykoside, b-Rezeptorenblocker, Diuretika), pp 67-86, Verlag Dr. med. D. Straube, Erlangen

• Oelkers W, Rawer C, Wiederholt M, Schöneshöfer M, Palicki H (1977) [Catamnestic and endocrinological investigations in women with idiopathic edema]. Klin. Wochenschr. 55: 495-502. [PubMed] [PDF]

1976

• Ebel H, Aulbert E, Merker HJ (1976) Isolation of the basal and lateral plasma membranes of rat kidney tubule cells. Biochim. Biophys. Acta 433: 531-546. [PubMed]

• Ebel H, Gebhardt A, Aulbert E (1976) Protein composition of kidney cell membranes. In: Intestinal ion transport, ed. J.W.L. Robinson, MTP Press Ltd. Lancaster, p. 96-98 [Review]

• Hierholzer K, Wiederholt M (1976) Some aspects of distal tubular solute and water transport. Kidney Int. 9: 198-213 [PubMed reference]

• Ruf W, Ebel H (1976) (Na⁺K⁺)-activated ATPase in human cornea. Distribution within the cornea and properties of the enzyme from epithelial cells. Pflügers Arch. 366: 203-210. [PubMed] [PDF]

• Schurek HJ, Aulbert E, Ebel H (1976) The effect of Ca ion antagonist verapamil on ouabain inhibition of renal sodium reabsorption. Studies in the isolated perfused rat kidney. Curr. Probl. Clin. Biochem. 6: 281-290 [PubMed]

• Ullrich KJ, Hierholzer K (1976) Physiologie der Niere. In: Sarre H: Nierenkrankheiten. Georg Thieme Verlag, 4. neubearbeitete und erweiterte Auflage, Stuttgart [Textbook of Nephrology]

1975

• Ebel H, Sharp GWG (1975) Renal adenylate cyclase-effects of diuretics. Eur. J. Pharmacol. 34: 273-281 [PubMed]

• Gutsche HU, Müller-Suur R, Hegel U, Hierholzer K, Lüderitz S (1975) A new method for intratubular blockade in micropuncture experiments. Pflügers Arch. 354: 197-202 [PubMed]

• Hierholzer K (1975) [Regulation of electrolyte metabolism through membrane transport] Verh. Dtsch. Ges. Inn. Med. 81: 739-754 [PubMed reference]

• Khuri RN, Strieder N, Wiederholt M, Giebisch G (1975) Effects of graded solute diuresis on renal tubular sodium transport in the rat. Am. J. Physiol. 228: 1262-1268 [PubMed] [PDF]

• Müller-Suur R, Gutsche HU, Samwer KF, Oelkers W, Hierholzer K (1975) Tubuloglomerular feedback in rat kidneys of different renin contents. Pflügers Arch. 359: 33-56 [PubMed] [PDF]

• Schurek HJ, Aulbert E, Ebel H (1975) Influence of ouabain and ethacrynic acid on sodium transport and NaK-ATPase activity in the isolated perfused rat kidney. Curr. Probl. Clin. Biochem. 4: 162-168 [PubMed reference]

• Schurek HJ, Brecht JP, Lohfert H, Hierholzer K (1975) The basic requirements for the function of the isolated cell free perfused rat kidney. Pflügers Arch. 354: 349-365 [PubMed] [PDF]

1974

• Ebel H (1974) Effect of diuretics on renal NaK-ATPase and adenyl cyclase. Naunyn Schmiedebergs Arch. Pharmacol. 281(3): 301-314 [PubMed reference]

• Fischer F, Voigt G, Liegl O, Wiederholt M (1974) Effect of pH on potential difference and short circuit current in the isolated human cornea. Pflügers Arch. 349: 119-131 [PubMed reference]

• Hierholzer K, Lange S (1974) The effects of adrenal steroids on renal function. In: Thurau K: MTP International Review of Science, Kidney and Urinary Tract Physiology. Butterworths University Park Press, S. 273-319 [Review]

• Hierholzer K, Müller-Suur R, Gutsche HU, Butz M, Lichtenstein I (1974) Filtration in surface glomeruli as regulated by flow rate through the Loop of Henle. Pflügers Arch. 352: 315-337  [PubMed reference] [PDF]

• Lange S, Hegel U, Hierholzer K (1974) Die Wirkung von Aldosteron auf den transepithelialen Salztransport und ihre Untersuchung mit elektrophysiologischen Methoden. Med. Klinik 69: 1478-1488 [PubMed reference]

• Lichey HJ, Fischer F, Wiederholt M (1974) Intracellular potentials in the isolated human cornea. Pflügers Arch. 346: 351-360 [PubMed reference] [PDF]

• Strieder N, Khuri R, Wiederholt M, Giebisch G (1974) Studies on the renal action of ouabain in the rat. Effects in the non-diuretic state. Pflügers Arch. 349: 91-107 [PubMed reference] [PDF]

• Wiederholt M, Schoormans W, Hansen L, Behn C (1974) Sodium conductance changes by aldosterone in the rat kidney. Pflügers Arch. 348: 155-165 [PubMed reference] [PDF]

• Wiederholt M, Agulian SK, Khuri RN (1974) Intracellular potassium in the distal tubule of the adrenalectomized and aldosterone treated rat. Pflügers Arch. 347: 117-123 [PubMed reference] [PDF]

1973

• Behn C, Brecht JP, Lübbemeier A, Wiederholt M (1973) Arterial pressure elevation in response to inhibitors of protein synthesis. Pflügers Arch. 339: 85-95 [PubMed reference] [PDF]

• Sharp GW, Hynie S, Ebel H, Parkinson DK, Witkum P (1973) Properties of adenylate cyclase in mucosal cells of the rabbit ileum and the effect of cholera toxin. Biochim. Biophys. Acta 309: 339-348 [PubMed reference]

• Wiederholt M, Schoormans W, Fischer F, Behn C (1973) Mechanism of action of aldosterone on potassium transfer in the rat kidney. Pflügers Arch. 345: 159-178 [PubMed reference] [PDF]

1972

• Ebel H, Ehrich J, De Santo NG, Doerken U (1972) Plasma membranes of the kidney. III influence of diuretics on ATPase activity. Pflügers Arch. 335: 224-234 [PubMed reference] [PDF]

• Hierholzer K, Butz M, Müller-Suur R, Lichtenstein I (1972) Pressure measurements in proximal surface tubules of the rat-single nephron filtration rate and tubuloglomerular feedback. Yale J. Biol. Med. 45: 224-232 [PubMed reference]

• Hierholzer K, Froese P (1972) Optimale Therapie mit Diuretika. Dtsch. Med. J. 23: 85-92 [PubMed reference]

• Parkinson DK, Ebel H, DiBona DR, Sharp GW (1972) Localization of the action of cholera toxin on adenyl cyclase in mucosal epithelial cells of rabbit intestine. J. Clin. Invest. 51: 2292-2298 [PubMed reference]

• Wiederholt M (1972) A new method for studying the function of the descending part of the proximal tubule in vivo. Yale J. Biol. Med. 45: 439-445 [PubMed reference]

• Wiederholt M, Behn C, Schoormans W, Hansen L (1972) Effect of aldosterone on sodium and potassium transport in the kidney. J. Steroid. Biochem. 3: 151-159 [PubMed reference]

1971

• De Santo NG, Ebel H, Hierholzer K (1971) Plasma cell membranes of the rat kidney. II. ATPase activities in adrenalectomized rats with and without steroid hormone substitution. Pflügers Arch. 324: 26-42 [PubMed reference] [PDF]

• De Santo NG, Natzschka JC, Lichtenstein I, Ebel H, Hierholzer K (1971) Studi di micropuntura renale nella nefropatia bilirubinica [Studies of renal micropuncture in bilirubin nephropathy]. Minerva Nefrologica 18: 159-161 [PubMed reference]

• Ebel H, De Santo NG, Hierholzer K (1971) Plasma cell membranes of the rat kidney. I. Purification and properties of cell membrane ATPase. Pflügers Arch. 324: 1-25 [PubMed reference] [PDF]

• Ebel H, Wolff JR, Dorn F, Günther T (1971) [The effect of hormones on the levels of electrolytes, ATPase and the structure of the endoplasmic reticulum in rat brain]. Z. Klin. Chem. Klin. Biochem. 9: 249-256 [PubMed reference]

• Hierholzer K, Hegel U (1971) Die osmotische Diurese. Med. Klinik 66: 255-264 [PubMed reference]

• Lohfert H, Lichtenstein I, Butz M, Hierholzer K (1971) Continuous measurement of renal intratubular pressures with a combined pressure transducer microperfusion system. Pflügers Arch. 327: 191-202 [PubMed reference] [PDF]

• Wiederholt M, Sullivan WJ, Giebisch G (1971) Potassium and sodium transport across single distal tubules of Amphiuma. J. Gen. Physiol. 57: 495-525 [PubMed reference]

1970

• De Santo NG, Ebel H, Hierholzer K (1970) [Mg⁺⁺-Na⁺-K⁺-ATPase in cellular membranes of the rat kidney. Effect of aldosterone, cortisone and aldosterone inhibitors] Minerva Nefrologica 17(3): 100-104 [PubMed reference]

1969

• Baldamus CA, Hierholzer K, Rumrich G, Stolte H, Uhlich E, Ullrich KJ, Wiederholt M (1969) [Sodium transport in the proximal tubules and the collecting ducts during variation in the sodium concentration of the surrounding interatitium]. Pflügers Arch. 310: 354-368 [PubMed reference] [PDF]

• De Santo NG, Ebel H, Hierholzer K (1969) Assenza di correlazione diretta transporto steroido-dipendente di sodio e Mg⁺⁺, Na⁺, K⁺-ATPase nelle membrane cellulari di rene di ratto [Absence of direct correlation between steroid-dependent transport of sodium, and Mg⁺⁺ Na⁺ K⁺ ATPase in the cellular membrane of the rat kidney] Minerva Nefrologica 16: 235-239 [PubMed reference]

• Hierholzer K (1969) Physiologie tubulärer Transportvorgänge. In: Klinische Pharmakologie der Diuretika. Hrsg. F Krück, W Leppla, Urban u. Schwarzenberg, München, p 24-36

• Hierholzer K, Stolte H (1969) The proximal and distal tubular action of adrenal steroids on Na-reabsorption. Nephron 6: 188-204. (Review) [PubMed reference]

• Hierholzer K, Ullrich KJ (1969) Grundzüge der Nierenphysiologie. In: Handb. d. exp. Pharmakologie. Hrsg.: H Herken, Bd. XXIV pp 1-61, Springer Verlag Berlin, Heidelberg, New York [Handbook article]

• Stolte H, Wiederholt M, Fuchs G, Hierholzer K (1969) Time course of development of transtubular sodium concentration differences in proximal surface tubules of the rat kidney. Micropuncture experiments in intact and adrenalectomized rats. Pflügers Arch. 313: 252-270 [PubMed reference] [PDF]

1969: Launching of the Institute of Clinical Physiology
1969: Gründung des Instituts für Klinische Physiologie