Joachim Mankertz

	*Research* *associate: Gastroenterolog*y
	Priv.-Doz. Dr. rer. nat. Joachim Mankertz - head of division - Federal Office of Consumer Protection and Food Safety (BVL) 12277 Berlin-Marienfelde, Germany Diedersdorfer Weg 1
	phone	+49 30 18412-2050
	FAX	+49 30 18412-2955
	e-mail	joachim.mankertz@bvl.bund.de
Joachim Mankertz		http://www.bvl.bund.de

Publications

Research topics

Grants

DFG KFO 104/2 (2005-2008) German Research Society, Clinical Research Unit "Immunpathogenese und Interventionsstrategien bei mukosalen Infektionen", coordinator Zeitz. Therein project 7: Schulzke, Fromm, Epple, Mankertz, "Barrier effects of intestinal infections and systemic-immunologic influences"
DFG FOR 721 (2006-2009) German Research Society, Research Unit "Molecular structure and function of the tight junction", coordinator Fromm. Therein project 2: Schulzke, Mankertz, Kroesen, "Tight junction proteins in inflammatory bowel diseases"

CV
1981 - 1987	Study of Biology, Freie Universitaet Berlin
1987	Diploma thesis "Expressionsklonierung antigener Epitope des Herpes simplex Virus 1"
1987 - 1990	Junior Researcher, Robert Koch-Institute, Berlin
1990	Doctoral thesis, Dr. rer. nat. (equiv. to PhD) "Untersuchung von Transkriptionseinheiten des porcinen Circovirus"
1990 - 1993	Junior Researcher, Dept. Clin. Molecular Biology and Tumor Genetics, Forschungszentrum für Umwelt und Gesundheit, München
1993 - 1998	Researcher, Dept. Biochemistry, Freie Universität Berlin
1998 - 2000	Researcher, Dept. Gastroenterology, Freie Universität Berlin
2000 - 2008	Senior Researcher, Dept. Gastroenterology, Charité, Campus Benjamin Franklin, Berlin
2004	Habilitation for Biochemistry and Pathobiochemistry
March 2008	Appointment @ Federal Office of Consumer Protection and Food Safety (BVL)

Previous research topics:

Virology

Transcription analysis of porcine circovirus (PCV)
Identification of a protein essential for replication of porcine circovirus
Low density lipoproteins as drug carriers in the therapy of macrophage-associated diseases
Mapping and characterization of the origin of DNA replication of porcine circovirus
Selective endocytosis of fluorothymidine and azidothymidine coupled to LDL into HIV infected mononuclear cells
Cell specific uptake of antiretroviral drugs: AZT coupled to LDL inhibits HIV replication in human macrophages
cis-acting elements in the lytic origin of DNA replication of Epstein-Barr virus
Conserved domains of glycoprotein B (gB) of the monkey virus, simian agent 8, identified by comparison with herpesvirus gBs
Conservation of a gene cluster including glycoprotein B in bovine herpesvirus type 2 (BHV-2) and herpes simplex virus type 1 (HSV-1)
Common epitopes of glycoprotein B map within the major DNA-binding proteins of bovine herpesvirus type 2 (BHV-2) and herpes simplex virus type 1 (HSV-1)