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2008 - 2009
De Santo NG, Fromm M, Russo F, Wiederholt M (2009) Klaus Hierholzer [1929-2007] and his impact on our understanding of the renal effects of steroid hormones. J. Nephrol. 22(S14): 159-178 [PubMed] [PDF]
De Santo NG, Fromm M, Russo F, Wiederholt M (2008) Klaus Hierholzer in memoriam: Klaus Hierholzer and his impact on the renal effects of steroid hormones. Arte Tipografica, Napoli, ISBN 978-88-89776-97-1, pp 48.
2002 - 2005
Thieme H, Steinhausen K, Ottlecz A, Lambrou GN, Strauss O, Wiederholt M, Rosenthal R (2005) Effects of unoprostone and endothelin-1 on L-type channel currents in human trabecular meshwork cells. Ophthalm. Res. 37(6): 293-300 [PubMed] [PDF]
Rosenthal R, Choritz L, Schlott S, Bechrakis NE, Jaroszewski J, Wiederholt M, Thieme H (2005) Effects of ML-7 and Y-27632 on carbachol- and endothelin-1-induced contraction of bovine trabecular meshwork. Exp. Eye Res. 80(6): 837-845 [PubMed] [WebPage] [PDF]
Stumpff F, Boxberger M, Krauss A, Rosenthal R, Meissner S, Choritz L, Wiederholt M, Thieme H (2005) Stimulation of cannabinoid (CB1) and prostanoid (EP2) receptors opens BKCa channels and relaxes ocular trabecular meshwork. Exp. Eye Res. 80(5): 697-708 [PubMed] [WebPage] [PDF]
Fidzinski P, Knoll A, Rosenthal R, Schrey A, Vescovi A, Koert U, Wiederholt M, Strauß O (2003) Electrophysiological response of cultured trabecular meshwork cells to synthetic ion channels. Chem. Biol. 10(1): 35-43 [PubMed] [Full text].
Strauss O, Rosenthal R, Dey D, Beninde J, Wollmann G, Thieme H, Wiederholt M (2002) Effects of protein kinase C on delayed rectifier K(+) channel regulation by tyrosine kinase in rat retinal pigment epithelial cells. Invest. Ophthalmol. Vis. Sci. 43(5): 1645-1654 [PubMed] [PDF]
2001
Thieme H, Stumpff F, Ottlecz A, Percicot CL, Lambrou GN, Wiederholt M (2001) Mechanisms of action of unoprostone on trabecular meshwork contractility. Invest. Ophthalmol. Vis. Sci. 42(13): 3193-3201 [PubMed] [WebPage]
Thieme H, Hildebrand J, Choritz L, Strauss O, Wiederholt M (2001) Muscarinic receptors of the M2 subtype in human and bovine trabecular meshwork. Graefe's Arch. Clin. Exp. Ophthalmol. 239: 310-315 [PubMed] [PDF]
Stumpff F, Boxberger M, Thieme H, Strauss O, Wiederholt M (2001) Flufenamic acid enhances current through maxi-K channels in the trabecular meshwork of the eye. Curr. Eye Res. 22(6): 427-437 [PubMed]
2000
Thieme H, Nuskovski M, Nass JU, Pleyer U, Strauss O, Wiederholt M (2000) Mediation of calcium-independent contraction in trabecular meshwork through protein kinase C and rho-A. Invest. Ophthalmol. Vis. Sci. 41(13): 4240-4246 [PubMed] [WebPage]
Wiederholt M, Stumpff F, Dörschner N (2000) Contractility of trabecular meshwork and ciliary muscle is modulated by the NO/cGMP system. In: Nitric oxide in the eye. Ed. S. Kashii, Springer Verlag, Tokyo, pp. 15-30
Wiederholt M, Thieme H, Stumpff F (2000) The regulation of trabecular meshwork and ciliary muscle contractility. Progr. Ret. Eye Res. 19(3): 271-295 [PubMed] [WebPage] [PDF]
Steinhausen K, Stumpff F, Strauss O, Thieme H, Wiederholt M (2000) Influence of muscarinic agonists and tyrosine kinase inhibitors on L-type Ca2+ channels in bovine and human trabecular meshwork cells. Exp. Eye Res. 70(3): 285-293 [PubMed] [PDF]
Stumpff F, Wiederholt M (2000) Regulation of trabecular meshwork contractility. Ophthalmologica 214(1): 33-53 [PubMed]
Strauss O, Buss F, Rosenthal R, Fischer D, Mergler S, Stumpff F, Thieme H (2000) Activation of neuroendocrine L-type channels (a1D subunits) in retinal pigment epithelial cells and brain neurons by pp60c-src. Biochem. Biophys. Res. Comm. 270(3): 806-810 [PubMed]
1999
Wiederholt M, Thieme H, Nass JU, Stumpff F (1999) Contractility of the trabecular meshwork: A target of treatment of glaucoma? In: Pathogenesis and risk factors of glaucoma. Eds. E. Gramer, F. Grehn. Springer Verlag, Berlin, Heidelberg, New York, pp. 108-116
Wiederholt M, Bräuer H, Bräuer B (1999) Excerpta ophthalmologica: Bildatlas zur Physiologie und Pathophysiologie der Mikrozirkulation des Auges. Med. Service, München, pp.1-96
Thieme H, Nass JU, Nuskovski M, Bechrakis NE, Stumpff F, Strauß O, Wiederholt M (1999) The effects of Protein Kinase C (PKC) on Trabecular Meshwork and Ciliary Muscle Contractility. Invest. Ophthalmol. Vis. Sci. 40(13): 3254-3261 [PubMed]
Thieme H, Nass JU, Nuskovski M, Wiederholt M (1999) The effects of the carbonic anhydrase inhibitors methazolamide, diclofenamide and dorzolamide on trabecular meshwork and ciliary muscle contractility. Exp. Eye Res. 69(4): 455-458 [PubMed reference] [PDF]
Thieme H, Wissinger B, Jandeck C, Christ-Adler M, Kraus H, Kellner U, Foerster MH (1999) A pedigree of Leber's hereditary optic neuropathy (LHON) with visual loss in childhood primarily in girls. Graefes Arch. Clin. Exp. Ophthalmol. 237: 714-719 [PubMed]
Strauß O, Steinhausen K, Mergler S, Stumpff F, Wiederholt M (1999) Involvement of protein tyrosine kinase in the InsP3-induced activation of Ca2+-dependent Cl- currents in cultured cells of the rat retinal pigment epithelium. J. Membr. Biol. 169: 141-153 [PubMed]
Stumpff F, Que Y, Boxberger M, Strauß O, Wiederholt M (1999) Stimulation of maxi-K channels in trabecular meshwork by tyrosine kinase inhibitors. Invest. Ophthalmol. Vis. Sci. 40: 1404-1417 [PubMed]
Valtink M, Engelmann K, Strauss O, Krüger R, Loliger C, Ventura AS, Richard G (1999) Physiological features of primary cultures and subcultures of human retinal pigment epithelial cells before and after cryopreservation for cell transplantation. Graefes Arch. Clin. Exp. Ophthalmol. 237(12): 1001-1006 [PubMed]
1998
Wiederholt M (1998) Nitric oxide and endothelin in aqueous humor outflow regulation. In: Nitric oxide and endothelin in the pathogenesis of glaucoma. Ed. I.O. Haefliger, J. Flammer, Lippincott-Raven Publishers, Philadelphia, pp. 168-177
Strauß O, Steinhausen K, Wienrich M, Wiederholt M (1998) Activation of Cl-conductance by protein kinase-dependent phosphorylation in cultured rat retinal pigment epithelial cells. Exp. Eye Res. 66: 35-42 [PubMed]
Wiederholt M, Stumpff F (1998) The trabecular meshwork and aqueous humor reabsorption. In: Current Topics in Membranes, Vol. 45 "The eye's aqueous humor: from secretion to glaucoma", Ed: M.M. Civan, Academic Press, San Diego, pp. 163-202
Wiederholt M, Groth J, Strauß O (1998) Protein tyrosine kinase pathways and the regulation of trabecular meshwork and ciliary muscle contractility. Invest. Ophthalmol. Vis. Sci. 39: 1012-1020 [PubMed]
Wiederholt M (1998) Direct involvement of trabecular meshwork in regulation of aqueous humor outflow. Curr. Opinion Ophthalmol. 9: 46-49 [PubMed]
Strauß O, Stumpff F, Mergler S, Wienrich M, Wiederholt M (1998) The Royal College of Surgeons rat: an animal model for inherited retinal degeneration with a still unknown genetical defect. Acta Anatomica 162: 101-111 [PubMed]
Mergler S, Steinhausen K, Wiederholt M, Strauß O (1998) Altered regulation of L-type channels by protein kinase C and protein tyrosine kinases as a pathophysiologic effect in retinal degeneration. FASEB J. 12: 1125-1134 [PubMed]
Wiederholt M (1998) Contractility of trabecular meshwork and ciliary muscle: Effects of prostaglandins. In: Prostaglandins in ophthalmology. Ed. M. Diestelhorst, Kaden Verlag, Heidelberg, pp. 31-38
Wiederholt M (1998) Pharmacological regulation of trabecular meshwork contractility. In: Fortbildung Glaukom, Band 1: Perfusion und Pharmakologie. Eds. K.G. Schmidt, L.E. Pillunat, Enke-Verlag, Stuttgart, pp. 19-28
Wiederholt M, Groth J, Strauß O (1998) Protein tyrosine kinase pathways and the regulation of trabecular meshwork and ciliary muscle contractility. Invest. Ophthalmol. Vis. Sci. 39: 1012-1020 [PubMed]
Mergler S, Steinhausen K, Wiederholt M, Strauß O (1998) Altered regulation of L-type channels by protein kinase C and protein tyrosine kinases as a pathophysiologic effect in retinal degeneration. FASEB J. 12: 1125-1134 [PubMed]
1996 - 1997
Gabelt BT, Wiederholt M, Clark AF, Kaufman Pl (1997) Anterior segment physiology following bumetanide inhibition of Na+, K+, Cl- cotransport. Invest. Ophthalmol. Vis. Sci. 38: 1700-1707 [PubMed]
Stumpff F, Strauß O, Boxberger M, Wiederholt M (1997) Characterization of maxi-K-channels in trabecular meshwork and their regulation by cGMP. Invest. Ophthalmol. Vis. Sci. 38: 1883-1892 [PubMed]
Strauß O, Mergler S, Wiederholt M (1997) Regulation of L-type calcium channels by protein tyrosine kinase (PTK) and protein kinase C (PKC) in cultured rat and human retinal pigment epithelial cells. FASEB J. 11: 859-867 [PubMed]
Strauß O, Wiederholt M, Wienrich M (1996) Activation of Cl- currents in cultured rat retinal pigment epithelial cells by intracellular applications of inositol-1,4,5-triphosphate: differences between rats with retinal dystrophy (RCS) and normal rats. J. Membr. Biol. 151: 189-200 [PubMed]
1995
Wiederholt M (1995) The ciliary epithelium of the eye as a model for acid-base related transport properties. In: Acid-base and electrolyte balance. Molecular, cellular, and clinical aspects. Eds. N.G. De Santo, G. Capasso, Istituto Italiano per gli Studi Filosofici, pp. 2-8.
Wiederholt M, Bielka S, Schweig F, Lütjen-Drecoll E, Lepple-Wienhues A (1995) Regulation of outflow rate and resistance in the perfused anterior segment of the bovine eye. Exp. Eye Res. 61: 223-234 [PubMed]
Wiederholt M, Berweck S, Helbig H (1995) Electrophysiological properties of cultured retinal capillary pericytes. In: Progress in Retinal and Eye Research, Vol. 14, No. 2, Eds. N.N. Osborne, G.J. Chader, Pergamon Press, Oxford - New York - Seoul - Tokyo, pp. 437-451.
Noske W, Strauß O, Levarlet B, Wiederholt M, Hirsch M (1995) Incomplete belts of tight junctions in cultured non-pigmented human ciliary epithelial cells. J. Submicrosc. Cytol. Pathol. 27: 1-8 [PubMed]
1994
Wiederholt M, Sturm A, Lepple-Wienhues A (1994) Relaxation of trabecular meshwork and ciliary muscle by release of nitric oxide. Invest. Ophthalmol. Vis. Sci. 35: 2515-2520 [PubMed]
Lepple-Wienhues A, Rauch R, Clark A, Grässmann A, Berweck S, Wiederholt M (1994) Electrophysiological properties of cultured human trabecular meshwork cells. Exp. Eye Res. 59: 305-311 [PubMed]
Berweck S, Lepple-Wienhues A, Stöß M, Wiederholt M (1994) Large conductance calcium-activated potassium channels in cultured retinal pericytes under normal and high-glucose conditions. Pflügers Arch. 427: 9-16 [PubMed]
Fromm M, Hegel U, Wiederholt M (1994) "Epithelien". In: Pathophysiologie des Menschen, Kapitel 5, K. Hierholzer und R.F. Schmidt eds., Chapman & Hall, Weinheim, pp 5.1-5.19. [Textbook of pathophysiology]
1993
Wiederholt M, Lepple-Wienhues A, Stahl F (1993) Contractile properties of trabecular meshwork and ciliary muscle. In: Basic aspects of glaucoma research, III, Ed. E. Lütjen-Drecoll. Schattauer, Stuttgart, New York, pp. 287-306
Wiederholt M, Helbig H, Korbmacher C (1993) Regulation of electrolyte transport mechanisms in ciliary epithelium. In: Basic aspects of glaucoma research, III, Ed. E. Lütjen-Drecoll. Schattauer, Stuttgart, New York, pp. 225-241
Hegel U, Fromm M, Kreusel K, Wiederholt M (1993) Bovine and porcine large intestine as model epithelia in a student lab course. Am. J. Physiol. 265: S10-S19 [PubMed]
Berweck S, Thieme H, Helbig H, Lepple-Wienhues A, Wiederholt M (1993) Effect of elevated glucose concentration on membrane voltage regulation in retinal capillary pericytes. Diabetes 42: 1347-1350 [PubMed]
Berweck S, Thieme H, Lepple-Wienhues A, Helbig H, Wiederholt M (1993) Insulin-induced hyperpolarization in retinal capillary pericytes. Invest. Ophthalmol. Vis. Sci. 34: 3402-3407 [PubMed]
1992
Wiek J, Krause M, Schade M, Wiederholt M, Hansen LL (1992) Haemorheological parameters in patients with retinal artery occlusion and anterior ischemic optic neuropathy. Brit. J. Ophthalmol. 76: 142-145 [PubMed]
Strauß O, Stahl F, Wiederholt M (1992) Elevation of cytosolic free calcium in cultured ciliary epithelial cells by histamine: effects of verapamil and staurosporine. J. Ocular Pharmacol. 8: 359-366 [PubMed]
Stahl F, Garus HJ, Lepple-Wienhues A, Wiederholt M (1992) Effect of histamine on membrane potential of cultured human nonpigmented ciliary epithelial cells. German J. Ophthalmol. 1: 62-66 [PubMed]
Stahl F, Gebauer B, Lepple-Wienhues A, Langenbeck-Groh G, Berweck S, Wiederholt M (1992) Characterization of acetylcholine- and endothelin-induced calcium entry in human ciliary muscle cells. Pflügers Arch. 422: 105-111 [PubMed]
Stahl F, Lepple-Wienhues A, Kuppinger M, Tamm E, Wiederholt M (1992) Electrogenic sodium-bicarbonate cotransport in human ciliary muscle cells. Am. J. Physiol. 262: C427-C435 [PubMed] [Full text, PDF]
Stahl F, Lepple-Wienhues A, Koch M, Wiederholt M (1992) Na+-dependent HCO3- transport and Na+/H+ exchange regulate pHi in human ciliary muscle cells. J. Membr. Biol. 127: 215-225 [PubMed]
Lepple-Wienhues A, Becker M, Stahl F, Berweck S, Hensen J, Noske W, Eichhorn M, Wiederholt M (1992) Endothelin-like immunoreactivity in the aqueous humour and in conditioned medium from cultured ciliary epithelial cells. Curr. Eye Res. 11: 1041-1046 [PubMed]
Lepple-Wienhues A, Stahl F, Wunderling D, Wiederholt M (1992) Effects of endothelin and calcium channel blockers on membrane voltage and intracellular calcium in cultured bovine trabecular meshwork. German J. Ophthalmol. 1: 159-163 [PubMed]
Helbig H, Kornacker S, Berweck S, Stahl F, Lepple-Wienhues A, Wiederholt M (1992) Membrane potentials in retinal capillary pericytes: Excitability and effect of vasoactive sustances. Invest. Ophthalmol. Vis. Sci. 33: 2105-2112 [PubMed]
Wiederholt M, Helbig H, Korbmacher C (1991) Ion transport across the ciliary epithelium: lessons from cultured cells and proposed role of carbonic anhydrase. In: Carbonic Anhydrase. Eds. F. Botre, G. Gross, B.T. Storey. VCH, Weinheim, New York, Basel, Cambridge, pp. 232-244
1991
Strauß O, Wiederholt M (1991) Transepithelial resistance of ciliary epithelial cells in culture: Functional modification by protamine and extracellular calcium. Comp. Biochem. Physiol. A 100: 987-993, 1991 [PubMed]
Stahl F, Lepple-Wienhues A, Kuppinger M, Schneider U, Wiederholt M (1991) Measurements of intracellular calcium and contractility in human ciliary muscle. Pflügers Arch. 418: 531-537 [PubMed]
Lepple-Wienhues A, Stahl F, Willner U, Schäfer R, Wiederholt M (1991) Endothelin-evoked contractions in bovine ciliary muscle and trabecular meshwork: interaction with calcium, nifedipine and nickel. Curr. Eye Res. 10: 983-989 [PubMed]
Lepple-Wienhues A, Stahl F, Wiederholt M (1991) Differential smooth muscle-like contractile properties of trabecular meshwork and ciliary muscle. Exp. Eye Res. 53: 33-38 [PubMed]
Fromm M, Hegel U, Wiederholt M (1991) Epithelien. In: Pathophysiologie des Menschen, Kapitel 5, K. Hierholzer und R.F. Schmidt eds., edition medizin VCH, Weinheim, S. 5.1-5.19
Coroneo MT, Korbmacher C, Stiemer B, Flügel C, Lütjen-Drecoll E, Wiederholt M (1991) Electrical and morphological evidence for heterogenous populations of cultured bovine trabecular meshwork cells. Exp. Eye Res. 52: 375-388 [PubMed]
1990
Wiek J, Schade M, Wiederholt M, Arntz HR, Hansen LL (1990) Haemorheological changes in patients with retinal vein occlusion after isovolaemic haemodilution. Brit. J. Ophthalmol. 74: 665-669 [PubMed]
Wiek J, Krause M, Wiederholt M, Hansen LL (1990) [Hemorheologic parameters in patients with giant cell arteritis before and after treatment with steroids]. Fortschr. Ophthalmol. 87: 671-674 [PubMed]
Wiederholt M, Jentsch TJ (1990) Cell culture of bovine corneal endothelial cells and its application to transport studies. In: Methods in Enzymology. (Eds. S. Fleischer, B. Fleischer), Vol. 192: Biomembranes Part W, Cellular and subcellular transport: Epithelial cells. Academic Press, San Diego, New York, Boston, London, Sydney, Tokyo, Toronto, pp. 571-582
Wiederholt M, Zadunaisky JA (1990) Electrolyte transport across the ciliary epithelium of the shark. In: Animal Nutrition and Transport Processes. 2. Transport, Respiration and Excretion: Comparative and Environmental Aspects, Eds. J.-P.Truchot and B. Lahlou, Comp. Physiol. Basel, Karger, vol 6, pp 171-184
Pahlitzsch T, Wyrobisch W, Kämpe C, Wiederholt M (1990) [Therapy of the ocular form of Behcet disease with cyclosporin A]. Klin. Monatsbl. Augenheilk. 196: 466-469 [PubMed]
Wiederholt M, Wiek J, Hansen LL (1990) Hämodilution bei Durchblutungsstörungen der Retina. Folia Ophthalmol. 15: 113-116
Helbig H, Korbmacher C, Wiederholt M (1990) [Mechanism of ascorbic acid transport in the aqueous humor]. Fortschr. Ophthalmol. 87: 421-424 [PubMed]
Korbmacher C, Helbig H, Coroneo MT, Erickson-Lamy KA, Stiemer B, Tamm E, Lütjen-Drecoll E, Wiederholt M (1990) Membrane voltage recordings in a primary cell line derived from human ciliary muscle. Invest. Ophthalmol. Vis. Sci. 31: 2420-2430 [PubMed]
1989
Coroneo MT, Helbig H, Korbmacher C, Wiederholt M (1989) Effect of hypotonic media on the membrane voltage of cultured bovine corneal endothelial cells. Curr. Eye Res. 8: 891-899 [PubMed]
Wiederholt M, Flügel C, Lütjen-Drecoll E, Zadunaisky JA (1989) Mechanically stripped pigmented and non-pigmented epithelium of the shark ciliary body: morphology and transepithelial electrical properties. Exp Eye Res. 49: 1031-1043 [PubMed]
Flügel C, Lütjen-Drecoll E, Zadunaisk JA, Wiederholt M (1989) Regional differences in the morphology and enzyme distribution of the spiny dogfish (Squalus acanthias) ciliary epithelium. Exp Eye Res. 49: 1097-1114 [PubMed]
Korbmacher C, Helbig H, Haller H, Erickson-Lamy KA, Wiederholt M (1989) Endothelin depolarizes membrane voltage and increases intracellular calcium concentration in human ciliary muscle cells. Biochem. Biophys. Res. Commun. 164: 1031-1039 [PubMed]
Hansen LL, Wiek J, Wiederholt M (1989) A randomised prospective study of treatment of non-ischaemic central retinal vein occlusion by isovolaemic haemodilution. Br. J. Ophthalmol. 73: 895-899 [PubMed]
Helbig H, Korbmacher C, Erb C, Nawrath M, Knuuttila KG, Wistrand P, Wiederholt M (1989) Coupling of 22Na and 36Cl uptake in cultured pigmented ciliary epithelial cells: a proposed role for the isoenzymes of carbonic anhydrase. Curr. Eye Res. 8: 1111-1119 [PubMed]
Helbig H, Korbmacher C, Stumpff F, Coca-Prados M, Wiederholt M (1989) Role of HCO3- in regulation of cytoplasmic pH in ciliary epithelial cells. Am. J. Physiol. 257: C696-C705 [PubMed] [Full text, PDF]
Helbig H, Korbmacher C, Wohlfarth J, Coca-Prados M, Wiederholt M (1989) Intracellular voltage recordings in bovine non-pigmented ciliary epithelial cells in primary culture. Curr. Eye Res. 8: 793-800 [PubMed]
Korbmacher C, Helbig H, Stahl F, Coroneo M, Haller H, Lindschau C, Quass P, Wiederholt M (1989) Continuous membrane voltage recordings in A10 vascular smooth muscle cells: effect of AVP. Am. J. Physiol. 257: C323-C332 [PubMed] [Full text, PDF]
Helbig H, Korbmacher C, Nawrath M, Erb C, Wiederholt M (1989) Sodium bicarbonate cotransport in cultured pigmented ciliary epithelial cells. Curr. Eye Res. 8: 595-598 [PubMed]
Helbig H, Korbmacher C, Wohlfarth J, Coroneo MT, Lindschau C, Quass P, Haller H, Coca-Prados M, Wiederholt M (1989) Effect of acetylcholine on membrane potential of cultured human nonpigmented ciliary epithelial cells. Invest. Ophthalmol. Vis. Sci. 30: 890-896 [PubMed]
Helbig H, Korbmacher C, Wohlfarth J, Coca-Prados M, Wiederholt M (1989) Electrical membrane properties of a cell clone derived from human nonpigmented ciliary epithelium. Invest. Ophthalmol. Vis. Sci. 30: 882-889 [PubMed]
Helbig H, Korbmacher C, Wohlfarth J, Berweck S, Kuhner D, Wiederholt M (1989) Electrogenic Na+-ascorbate cotransport in cultured bovine pigmented ciliary epithelial cells. Am. J. Physiol. 256: C44-C49 [PubMed] [Full text, PDF]
Korbmacher C, Helbig H, Forster C, Wiederholt M (1989) [Measuring intracellular pH in cultivated corneal epithelial cells]. Fortschr. Ophthalmol. 86: 279-282 [PubMed]
Hansen LL, Wiek J, Schade M, Muller-Stolzenburg N, Wiederholt M (1989) Effect and compatibility of isovolaemic haemodilution in the treatment of ischaemic and non-ischaemic central retinal vein occlusion. Ophthalmologica 199: 90-99 [PubMed]
Helbig H, Korbmacher C, Erb C, Nawrath M, Knuuttila KG, Wistrand P, Wiederholt M (1989) [Carbonic anhydrase and its function in ion transport in cultivated pigmented ciliary body epithelial cells]. Fortschr. Ophthalmol. 86: 474-477 [PubMed]
1988
Helbig H, Korbmacher C, Stumpff F, Coca-Prados M, Wiederholt M (1988) Na+/H+ exchange regulates intracellular pH in a cell clone derived from bovine pigmented ciliary epithelium. J. Cell Physiol. 137: 384-389 [PubMed]
Helbig H, Korbmacher C, Kuhner D, Berweck S, Wiederholt M (1988) Characterization of Cl-/HCO3- exchange in cultured bovine pigmented ciliary epithelium. Exp. Eye Res. 47: 515-523 [PubMed]
Korbmacher C, Helbig H, Forster C, Wiederholt M (1988) Characterization of Na+/H+ exchange in a rabbit corneal epithelial cell line (SIRC). Biochim. Biophys. Acta 943: 405-410 [PubMed]
Jentsch TJ, Korbmacher C, Janicke I, Fischer DG, Stahl F, Helbig H, Hollwede H, Cragoe EJ Jr, Keller SK, Wiederholt M (1988) Regulation of cytoplasmic pH of cultured bovine corneal endothelial cells in the absence and presence of bicarbonate. J. Membr. Biol. 103: 29-40 [PubMed]
Helbig H, Korbmacher C, Berweck S, Kuhner D, Wiederholt M (1988) Kinetic properties of Na+/H+ exchange in cultured bovine pigmented ciliary epithelial cells. Pflügers Arch. 412: 80-85 [PubMed]
Korbmacher C, Helbig H, Stahl F, Wiederholt M (1988) Evidence for Na/H exchange and Cl/HCO3 exchange in A10 vascular smooth muscle cells. Pflügers Arch. 412: 29-36 [PubMed]
Korbmacher C, Helbig H, Forster C, Wiederholt M (1988) Evidence for Na+/H+ exchange and pH sensitive membrane voltage in cultured bovine corneal epithelial cells. Curr. Eye Res. 7: 619-626 [PubMed]
Hoffmann F, von Keyserlingk HJ, Wiederholt M (1988) [Significance of transplantation antigens in keratoplasty]. Fortschr. Ophthalmol. 85: 186-189 [PubMed reference]
Keller SK, Jentsch TJ, Janicke I, Wiederholt M (1988) Regulation of intracellular pH in cultured bovine retinal pigment epithelial cells. Pflügers Arch. 411: 47-52 [PubMed]
Helbig H, Korbmacher C, Berweck S, Kuhner D, Wiederholt M (1988) [Culture of ciliary body epithelia and studies of ion transport]. Fortschr. Ophthalmol. 85: 42-45 [PubMed reference]
1987
Wiederholt M, Zadunaisky JA (1987) Effects of ouabain and furosemide on transepithelial electrical parameters of the isolated shark ciliary epithelium. Invest. Ophthalmol. Vis. Sci. 28: 1353-1356 [PubMed]
von Keyserlingk H, Offermann G, Wiederholt M, Hoffmann F (1987) The importance of HLA-DR matching in corneal transplant recipients treated with cyclosporine A. Transplant. Proc. 19: 2576-2578 [PubMed reference]
Wiederholt M (1987) [Electrolyte transport in the epithelium and endothelium of the cornea]. Fortschr. Ophthalmol. 84: 301-306 [PubMed reference]
Helbig H, Korbmacher C, Wiederholt M (1987) K+-conductance and electrogenic Na+/K+ transport of cultured bovine pigmented ciliary epithelium. J. Membr. Biol. 99: 173-186 [PubMed]
1986
Jentsch TJ, Matthes H, Keller SK, Wiederholt M (1986) Electrical properties of sodium bicarbonate symport in kidney epithelial cells (BSC-1). Am. J. Physiol. 1986 Dec;251(6 Pt 2):F954-68 [PubMed] [Full text, PDF]
Jentsch TJ, Janicke I, Sorgenfrei D, Keller SK, Wiederholt M (1986) The regulation of intracellular pH in monkey kidney epithelial cells (BSC-1). Roles of Na+/H+ antiport, Na+-HCO3(-)-(NaCO3-) symport, and Cl-/HCO3- exchange. J. Biol. Chem. 261: 12120-12127 [PubMed]
Jentsch TJ, Schwartz P, Schill BS, Langner B, Lepple AP, Keller SK, Wiederholt M (1986) Kinetic properties of the sodium bicarbonate (carbonate) symport in monkey kidney epithelial cells (BSC-1). Interactions between Na+, HCO3-, and pH. J. Biol. Chem. 261: 10673-10679 [PubMed]
Hoffmann F, Wiederholt M, Kossendrup D (1986) [Effect of cyclosporin A, dexamethasone and various preservatives on epithelial wound healing in the denervated guinea pig cornea]. Klin. Monatsbl. Augenheilkd. 189: 30-33 [PubMed]
Wiederholt M, Kossendrup D, Schulz W, Hoffmann F (1986) Pharmacokinetic of topical cyclosporin A in the rabbit eye. Invest. Ophthalmol. Vis. Sci. 27: 519-524 [PubMed]
Keller SK, Jentsch TJ, Koch M, Wiederholt M (1986) Interactions of pH and K+ conductance in cultured bovine retinal pigment epithelial cells. Am. J. Physiol. 250: C124-C137 [PubMed] [Full text, PDF]
Wiederholt M, Zadunaisky JA (1986) Membrane potentials and intracellular chloride activity in the ciliary body of the shark. Pflügers Arch. 407 Suppl 2: S112-S115 [PubMed]
Hoffmann F, von Keyserlingk HJ, Wiederholt M (1986) [Significance of HLA typing in corneal transplants with unfavorable prognosis in cyclosporin A therapy]. Fortschr. Ophthalmol. 83: 542-546. German [PubMed reference]
Wiederholt M, Kampe C, Hansen LL, Hövener G (1986) [Treatment of posterior uveitis with cyclosporin or prednisolone - one-year report of a randomized prospective study]. Fortschr. Ophthalmol. 83: 348-352. German [PubMed reference]
Wiederholt M, Zadunaisky JA (1986) Effect of calcium antagonist compound nisoldipine on transepithelial electrical parameters in the isolated frog cornea. J. Ocul. Pharmacol. 2: 159-164 [PubMed]
Hoffmann F, von Keyserlingk HJ, Wiederholt M (1986) Importance of HLA DR matching for corneal transplantation in high-risk cases. Cornea 5: 139-143 [PubMed reference]
Hoffmann F, Wiederholt M (1986) Topical cyclosporin A in the treatment of corneal graft reaction. Cornea 5: 129 [PubMed reference]
1985
Jentsch TJ, Schill BS, Schwartz P, Matthes H, Keller SK, Wiederholt M (1985) Kidney epithelial cells of monkey origin (BSC-1) express a sodium bicarbonate cotransport. Characterization by 22Na+ flux measurements. J. Biol. Chem. 260: 15554-15560 [PubMed]
Jentsch TJ, von der Haar B, Keller SK, Wiederholt M (1985) Response of the intracellular potentials of cultured bovine lens cells to ions and inhibitors. Exp. Eye Res. 41: 131-144 [PubMed]
Hoffmann F, Wiederholt M (1985) [Local treatment of corneal transplants in the human with cyclosporin A]. Klin. Monatsbl. Augenheilkd. 187: 92-96 [PubMed]
Kana JS, Wiederholt M (1985) Effect of corticosteroids on electrolyte transport of the isolated human and rabbit lens. Curr. Eye Res. 4: 461-465 [PubMed]
Jentsch TJ, Keller SK, Wiederholt M (1985) Ion transport mechanisms in cultured bovine corneal endothelial cells. Curr. Eye Res. 4: 361-369 [PubMed]
Jentsch TJ, Matthes H, Keller SK, Wiederholt M (1985) Anion dependence of electrical effects of bicarbonate and sodium on cultured bovine corneal endothelial cells. Pflügers Arch. 403: 175-185 [PubMed]
Hansen LL, Danisevskis P, Arntz HR, Hovener G, Wiederholt M (1985) A randomised prospective study on treatment of central retinal vein occlusion by isovolaemic haemodilution and photocoagulation. Br. J. Ophthalmol. 69: 108-116 [PubMed]
Jentsch TJ, Stahlknecht TR, Hollwede H, Fischer DG, Keller SK, Wiederholt M (1985) A bicarbonate-dependent process inhibitable by disulfonic stilbenes and a Na+/H+ exchange mediate 22Na+ uptake into cultured bovine corneal endothelium. J. Biol. Chem. 260: 795-801 [PubMed]
Hoffmann F, Wiederholt M (1985) Local treatment of necrotizing scleritis with cyclosporin A. Cornea 4: 3-7 [PubMed]
Hansen LL, Hövener G, Mercks C, Tavakolian U, Wiederholt M (1985) [Isovolemic hemodilution in patients with retinal branch vein occlusion]. Fortschr. Ophthalmol. 82: 290-292. German [PubMed reference]
Kossendrup D, Wiederholt M, Hoffmann F (1985) Influence of cyclosporin A, dexamethasone, and benzalkonium chloride (BAK) on corneal epithelial wound healing in the rabbit and guinea pig eye. Cornea 4: 177-181 [PubMed]
Wiederholt M, Jentsch TJ, Keller SK (1985) Electrogenic sodium-bicarbonate symport in cultured corneal endothelial cells. Pflügers Arch. 405 Suppl 1: S167-S171 [PubMed]
1984
Kana JS, Wiederholt M (1984) Corticosteroids and the active ion transport of the isolated human lens. Ann. Ophthalmol. 16: 1034-1039 [PubMed]
Wiederholt M, Keller S, Krolik A, Jentsch TJ (1984) The calcium antagonist nisoldipine stimulates the electrolyte transport of the isolated frog skin. Biochem. Pharmacol. 33: 2926-2928 [PubMed reference]
Wiederholt M, Hampel J, Belkien L, Oelkers W (1984) Aldosterone secretion, measurements of membrane potential and intracellular potassium activity in the isolated adrenal zone glomerulosa. FEBS Lett. 174: 211-214 [PubMed]
Wiederholt M, Zadunaisky JA (1984) Decrease of intracellular chloride activity by furosemide in frog retinal pigment epithelium. Curr. Eye Res. 3: 673-675 [PubMed]
Cohen B, Giebisch G, Hansen LL, Teuscher U, Wiederholt M (1984) Relationship between peritubular membrane potential and net fluid reabsorption in the distal renal tubule of Amphiuma. J. Physiol. (Lond.) 348: 115-134 [PubMed]
Jentsch TJ, Keller SK, Koch M, Wiederholt M (1984) Evidence for coupled transport of bicarbonate and sodium in cultured bovine corneal endothelial cells. J. Membr. Biol. 81: 189-204 [PubMed]
Jentsch TJ, Koch M, Bleckmann H, Wiederholt M (1984) Effect of bicarbonate, pH, methazolamide and stilbenes on the intracellular potentials of cultured bovine corneal endothelial cells. J. Membr. Biol. 78: 103-117 [PubMed]
1983
Danisevskis P, Hansen LL, Arntz HR, Hovener G, Wiederholt M (1983) [Treatment of central retinal vein occlusion by isovolemic hemodilution and photocoagulation]. Fortschr. Ophthalmol. 80: 173-175 [PubMed reference]
Wiederholt M, Schmidt DK, Eggebrecht R, Zimmermann J, Fischer FH (1983) Adrenergic regulation of sodium and chloride transport in the isolated cornea of rabbit and man. Graefes Arch. Clin. Exp. Ophthalmol. 220: 240-244 [PubMed]
1982
Kana JS, Hoffmann F, Buchen R, Krolik A, Wiederholt M (1982) Rabbit corneal allograft survival following topical administration of cyclosporin A. Invest. Ophthalmol. Vis. Sci. 22: 686-690 [PubMed]
Fischer FH, Wiederholt M (1982) Human precorneal tear film pH measured by microelectrodes. Graefes Arch. Clin. Exp. Ophthalmol. 218: 168-170 [PubMed]
Kana JS, Hoffmann F, Buchen R, Krolik A, Wiederholt M (1982) [Effect of local administration of cyclosporin A on corneal graft survival in the rabbit]. Fortschr. Ophthalmol. 79: 132-134. German. [PubMed reference]
1981
Platsch KD, Wiederholt M (1981) Intracellular potassium activity and cell membrane potential of the isolated human and rabbit lens. Exp. Eye Res. 33: 467-478 [PubMed reference]
Platsch KD, Wiederholt M (1981) Effect of ion substitution and ouabain on short circuit current in the isolated human and rabbit lens. Exp. Eye Res. 32: 615-625 [PubMed reference]
Wiederholt M (1981) Hemodilution in retinal hypoperfusion. Bibl. Haematol. 47: 185-191 [PubMed reference]
Wiederholt M (1981) [Hemodilution in ocular circulation disorders]. Verh. Dtsch. Ges. Inn. Med. 87: 1354-1357 [PubMed reference]
Hansen LL, Schilling AR, Wiederholt M (1981) Effect of calcium, furosemide and chlorothiazide on net volume reabsorption and basolateral membrane potential of the distal tubule. Pflügers Arch. 389: 121-126 [PubMed]
1980
Wiederholt M, Danisevskis P, Hansen LL, Lichey HJ, Platsch KD (1980) The effects of extracellular potassium, ouabain, and prostaglandins on intracellular potassium activity in sheep cardica Purkinje fibers. Pflügers Arch. 388: 169-175 [PubMed]
Wiederholt M (1980) Physiology of epithelial transport in the human eye. Klin. Wochenschr. 58: 975-984 [PubMed reference]
Wiederholt M, Leonhardt H, Schmid-Schonbein H, Hager H (1980) [Treatment of central retinal venous and arterial occlusion by isovolemic hemodilution]. Klin. Monatsbl. Augenheilkd. 177: 157-164. German [PubMed]
Wiederholt M, Hansen LL (1980) Amphiuma kidney as a model for distal tubular transport studies. Contrib. Nephrol. 19: 28-32 [PubMed reference]
1979
Wieland R, Wiederholt M, Hager H (1979) [Clinical and experimental evaluation of hydrophilic contact lenses for continuous-wear]. Klin. Monatsbl. Augenheilkd. 175: 664-966 [PubMed]
Hansen LL, Koch M, Platsch KD, Wiederholt M (1979) Intracellular potassium activity of isolated human and rabbit corneal epithelium. Exp. Eye Res. 29: 367-378 [PubMed reference]
Wiederholt M, Koch M (1979) Effect of intraocular irrigating solutions on intracellular membrane potentials and swelling rate of isolated human and rabbit cornea. Invest. Ophthalmol. Vis. Sci. 18: 313-317 [PubMed]
1978
Wiederholt M, Koch M (1978) Intracellular potentials of isolated rabbit and human corneal endothelium. Exp. Eye Res. 27: 511-518 [PubMed reference]
Fischer FH, Wiederholt M (1978) The pH dependency of sodium and chloride transport in the isolated human cornea. Invest. Ophthalmol. Vis. Sci. 17: 810-813 [PubMed]
Wiederholt M, Koch M (1978) Intracellular potentials of isolated rabbit and human corneal epithelium. Exp. Eye Res. 26: 629-640 [PubMed reference]
Fischer FH, Schmitz L, Hoff W, Schartl S, Liegl O, Wiederholt M (1978) Sodium and chloride transport in the isolated human cornea. Pflügers Arch. 373: 179-188 [PubMed]
1975 - 1977
Oelkers W, Rawer C, Wiederholt M, Schoneshofer M, Palicki H (1977) [Catamnestic and endocrinological investigations in women with idiopathic edema]. Klin. Wochenschr. 55: 495-502 [PubMed]
Hierholzer K, Wiederholt M (1976) Some aspects of distal tubular solute and water transport. Kidney Int. 9: 198-213 [PubMed reference]
Khuri RN, Strieder N, Wiederholt M, Giebisch G (1975) Effects of graded solute diuresis on renal tubular sodium transport in the rat. Am. J. Physiol. 228: 1262-1268 [PubMed] [Full text, PDF]
1974
Strieder N, Khuri R, Wiederholt M, Giebisch G (1974) Studies on the renal action of ouabain in the rat. Effects in the non-diuretic state. Pflügers Arch. 349: 91-107 [PubMed reference]
Fischer F, Voigt G, Liegl O, Wiederholt M (1974) Effect of pH on potential difference and short circuit current in the isolated human cornea. Pflügers Arch. 349: 119-131 [PubMed reference]
Wiederholt M, Schoormans W, Hansen L, Behn C (1974) Sodium conductance changes by aldosterone in the rat kidney. Pflügers Arch. 348: 155-165 [PubMed reference]
Wiederholt M, Agulian SK, Khuri RN (1974) Intracellular potassium in the distal tubule of the adrenalectomized and aldosterone treated rat. Pflügers Arch. 347: 117-123 [PubMed reference]
Lichey HJ, Fischer F, Wiederholt M (1974) Intracellular potentials in the isolated human cornea. Pflügers Arch. 346: 351-360 [PubMed reference]
1972 - 1973
Wiederholt M, Schoormans W, Fischer F, Behn C (1973) Mechanism of action of aldosterone on potassium transfer in the rat kidney. Pflügers Arch. 345: 159-178 [PubMed reference]
Behn C, Brecht JP, Lübbemeier A, Wiederholt M (1973) Arterial pressure elevation in response to inhibitors of protein synthesis. Pflügers Arch. 339: 85-95 [PubMed reference]
Wiederholt M (1972) A new method for studying the function of the descending part of the proximal tubule in vivo. Yale J. Biol. Med. 45: 439-445 [PubMed reference]
Wiederholt M, Behn C, Schoormans W, Hansen L (1972) Effect of aldosterone on sodium and potassium transport in the kidney. J. Steroid. Biochem. 3: 151-159 [PubMed reference]
1969 - 1971
Wiederholt M, Sullivan WJ, Giebisch G (1971) Potassium and sodium transport across single distal tubules of Amphiuma. J. Gen. Physiol. 57: 495-525 [PubMed reference]
Baldamus CA, Hierholzer K, Rumrich G, Stolte H, Uhlich E, Ullrich KJ, Wiederholt M (1969) [Sodium transport in the proximal tubules and the collecting ducts during variation in the sodium concentration of the surrounding interatitium]. Pflügers Arch. 310: 354-368 [PubMed reference]
Stolte H, Wiederholt M, Fuchs G, Hierholzer K (1969) Time course of development of transtubular sodium concentration differences in proximal surface tubules of the rat kidney. Micropuncture experiments in intact and adrenalectomized rats. Pflügers Arch. 313: 252-270 [PubMed reference]
1968
Wiederholt M, Wiederholt B (1968) [Influence of dexamethasone on water and electrolyte excretion in adrenalectomized rats]. Pflügers Arch. 302: 57-78 [PubMed reference]
Wiederholt M, Langer KH, Thoenes W, Hierholzer K (1968) [Functional and morphologic investigation of proximal and distal convolutions of rat kidney under the influence of the split-oil droplet method]. Pflügers Arch. 302: 166-191 [PubMed reference]
Langer KH, Thoenes W, Wiederholt M (1968) [Light and electron microscopic investigations of proximal convoluted tubules of the rat kidney after intraluminal injection of oil]. Pflügers Arch. 302: 149-165 [PubMed reference]
Stolte H, Brecht JP, Wiederholt M, Hierholzer K (1968) [Influence of adrenalectomy and glucocorticoid hormones on water permeability of superficial nephron segments in the rat kidney]. Pflügers Arch. 299: 99-127 [PubMed reference]
Wiederholt M, Hierholzer K, Senft G, Herken H (1968) [Localization of natriuretic action of 6-aminonicotinamide in rat kidney]. Naunyn Schmiedebergs Arch. Exp. Pathol. Pharmakol. 261: 143-151 [PubMed reference]
1965 - 1967
Wiederholt M, Hierholzer K, Windhager EE, Giebisch G (1967) Microperfusion study of fluid reabsorption in proximal tubules of rat kidneys. Am. J. Physiol. 213: 809-818 [PubMed reference]
Thoenes W, Langer KH, Wiederholt M (1966) [The resorption of ferritin in the proximal convolution of the rat kidney (following intratubular administration by micro-puncture)]. Klin. Wochenschr. 44: 1379-1381 [PubMed reference]
Wiederholt M (1966) [Micropuncture research on the proximal and distal convolution of the rat kidney on the effect of actinomycin D on mineralocorticoid-dependent sodium transport]. Pflügers Arch. 292: 334-342 [PubMed reference]
Wiederholt M, Stolte H, Brecht JP, Hierholzer K (1966) [Micropuncture research on the effect of aldosterone, cortisone and dexamethasone on renal sodium resorption in adrenalectomized rats]. Pflügers Arch. 292: 316-333 [PubMed reference]
Hierholzer K, Wiederholt M, Stolte H (1966) [The impairment of sodium resorption in the proximal and distal convolution of adrenalectomized rats]. Pflügers Arch. 291: 43-62 [PubMed reference]
Thoenes W, Hierholzer K, Wiederholt M (1965) [Fixation of renal tubules in vivo by microperfusion in light and electron microscopic studies]. Klin. Wochenschr. 43: 794-795 [PubMed reference]
