Priv.-Doz. Dr. rer. nat.
Jörg Piontek
Research Associate


Orcid ID
 +49 30 450-514535
 +49 30 450-514962



Research topics

- Molecular structure of single claudins
- Molecular arrangement of claudin heteromers
- "TJ-Train", project A2: Structure-based modification of Clostridium perfringens enterotoxin to target claudins
- Tight junctions of the blood-brain barrier
- Imaging of tight junction morphology and function



Grants German Research Foundation (DFG)

2021 - 2023


DFG Research Grant (PI 837/4-2) "Molekulare Architektur Claudin-basierender Tight Junction-Stränge und parazellulärer Ionenkanäle"

et al.

DFG major instrumentation (Großgerät, 700 T€) STED superresolution confocal microscope, consortium project: Piontek J
2017 - 2022 Piontek, Krause

Project A2, "Structure-based modification of Clostridium perfringens enterotoxin to target claudins", in:
DFG Research Training Group (GRK 2318) "Tight junctions and their proteins: molecular features and actions in health and disease (TJ-Train)"

2017 Bachmann (Anatomy)

DFG major instrumentation (INST 335/596-1 FUGG) Field emission scanning electron microscope (FESEM), consortium project: Fromm M, Krug SM, Piontek J "Paracellular versus transcytotic macromolecule passage / Organization of claudins in nanodomains"

2016 - 2019 Piontek, Krause DFG Research Grant (PI 837/4-1) "Molecular architekture of claudin-based tight junction strands and paracellular ion channels"
2009 - 2013 Piontek

DFG Research Grant (PI 837/2-1) "Molecular organization of heteropolymer tight junction strands"

2010 - 2012 Krause, Piontek Project TP6, "Molecular and structural patterns of paracellular pores formed by subtype-dependent claudin-claudin interactions in tight junctions", in
DFG Research Unit 721
(FOR 721/2) "Molecular structure and function of the tight junction"


1991 - 1993 Study of biology, University of Kaiserslautern
1994 - 1996 Study of biology, University of Heidelberg
1997 Diploma thesis (Dipl. Biol.) "Analysis of the expression and localization of microtubule-associated proteins in human model neurons", University of Heidelberg, Priv.-Doz. Dr. Roland Brandt
1997 - 2002 PhD thesis (Dr. rer. nat.) "Generation of monoclonal antibodies against proteins of the neuronal membrane cortex and investigation of gravin-signaling complexes in human model neurons", Interdisciplinary Center for Neurosciences (IZN), University of Heidelberg, Prof. Dr. Roland Brandt
2002 - 2003 Research Associate, Tissue engineering, ALVITO Biotechnologie GmbH, Kleinmachnow
2003 - 2009 Research Associate, group "Molecular cell physiology", Priv.-Doz. Dr. Ingolf Blasig, Leibniz-Institut für molekulare Pharmakologie (FMP), Berlin
2009 - 2012 Project leader, Leibniz-Institut für molekulare Pharmakologie (FMP), Berlin
since 2012 Visiting Professor, Guangdong Medical College, Zhanjiang, China
since 04.2013 Research Associate, Institut für Klinische Physiologie, Charité – Universitätsmedizin Berlin
11.07.2016 Habilitation for "Privatdozent" (US eqivalent "associate professor")