Projekte und Promotionsthemen 

     A:  Tight junction molecules, structure and function

Dorothee Günzel*
Institut für Klinische Physiologie, Campus Benjamin Franklin, Charité - Universitätsmedizin Berlin
"Impedance analysis of epithelial barrier properties"
PhD doctoral student, 2^nd cohort: Saeed Khomeijani Farahani
PhD doctoral student, 1^st cohort: Roman Mannweiler
MD doctoral student, 1^st cohort: Ahmad Mouna

Jörg Piontek¹*, Gerd Krause^2
1Institut für Klinische Physiologie, Campus Benjamin Franklin, Charité - Universitätsmedizin Berlin
²Structural Bioinformatics & Protein Design, Leibniz-Forschungsinstitut für Molekulare Pharmacologie (FMP), Berlin-Buch
"Structure-based modification of Clostridium perfringens enterotoxin to target claudins"
PhD doctoral student, 2^nd cohort: Ayk Waldow
PhD doctoral student, 1^st cohort: Laura-Sophie Beier

Michael Fromm*, Jörg-Dieter Schulzke*
Institut für Klinische Physiologie, Campus Benjamin Franklin, Charité - Universitätsmedizin Berlin
"Structural conditions of claudin-based water and cation channels"
PhD doctoral student, 2^nd cohort: Fabián Martínez-Perafán
PhD doctoral student, 1^st cohort: Carlos Ayala-Torres

Martin Lehmann, Volker Haucke*
Leibniz-Forschungsinstitut für Molekulare Pharmakologie (FMP), Berlin-Buch
"Dynamic super-resolution imaging of tight junction components, lipids and Ions"
PhD doctoral student, 2^nd cohort: Rozemarijn van der Veen
PhD doctoral student, 1^st cohort: Hannes Gonschior

     B:  Tight junction development and regulation

Thomas Willnow*, Annabel Christ
Max-Delbrück-Centrum für Molekulare Medizin (MDC), Berlin-Buch
"The endocytic receptor LRP2 serves as a central hub for dynamic cellular remodelling in neuronal stem cells and neural crest cells in the developing neural tube"
PhD doctoral student, 2^nd cohort: Sher Min Mak
PhD doctoral student, 1^st cohort: Izabela Kowalczyk

Michael Hummel¹, Britta Siegmund²*
¹Sektion Molekularpathologie am Institut für Pathologie, Charité, CCM
²Medizinische Klinik m.S. Gastroenterologie, Infektiologie & Rheumatologie, Charité, CBF
"Loss of epithelial polarity as a mechanism in inflammation-induced carcinogenesis"
PhD doctoral student, 2^nd cohort: Violaine Dony
PhD doctoral student, 1^st cohort: Danielle Cardoso-Silva

Dominik Müller*
Klinik für Pädiatrie m.S. Nephrologie, Charité - Universitätsmedizin Berlin, Campus Virchow-Klinikum
"Claudins of the thick ascending limb and nephrocalcinosis"
PhD doctoral student, 2^nd cohort: Amr Al-Shebel
PhD doctoral student, 1^st cohort: Murat Seker

Kai Schmidt-Ott*
Medizinische Klinik mit Schwerpunkt Nephrologie und Internistische Intensivmedizin, Charité - Universitätsmedizin Berlin and Max-Delbrück-Centrum für Molekulare Medizin in der Helmholtz-Gemeinschaft (MDC)
"Systems level assessment of epithelial barriers in the kidney"
PhD doctoral student, 2^nd cohort: Shuang Cao
PhD doctoral student, 1^st cohort: Janna Leiz
MD doctoral student, 1^st cohort: Alexander Holler

     C:  Tight junction modulation in disease

Jörg-Dieter Schulzke¹*, Hanno Troeger^2
1Institut für Klinische Physiologie, Campus Benjamin Franklin, Charité - Universitätsmedizin Berlin
²Med. Klinik m.S. Gastroenterologie, Infektiologie & Rheumatologie, CBF, Charité - Universitätsmedizin Berlin
"Bacterial toxins’ impact on epithelial tight junctions"
PhD doctoral student, 2^nd cohort: Martina Schneemann
PhD doctoral student, 1^st cohort: Praveen Kumar Nattramilarasu
MD doctoral student, 1^st cohort: Karem Awad
MD doctoral student, 1^st cohort: Lucas Heils
MD doctoral student, 1^st cohort: Sholpan Omarova
MD doctoral student, 1^st cohort: Eduard Butkevych

Susanne Krug*, Michael Fromm*
Institut für Klinische Physiologie, Campus Benjamin Franklin, Charité - Universitätsmedizin Berlin
"Interaction of immune cells and TJ proteins in IBD"
PhD doctoral student, 2^nd cohort: Lena Voges
PhD doctoral student, 1^st cohort: Jia-Chen E. Hu

Michael Schumann, Britta Siegmund*
Medizinische Klinik m.S. Gastroenterologie, Infektiologie & Rheumatologie, Campus Benjamin Franklin, Charité - Universitätsmedizin Berlin
"Epithelial barrier function secondary to defective epithelial polarity – a mechanism in celiac disease initiation?"
PhD doctoral student, 2^nd cohort: Subhakankha Manna
PhD doctoral student, 1^st cohort: Deborah Delbue
MD doctoral student, 1^st cohort: Daphni Siampli

Hans-Jörg Epple*, Thomas Schneider
Medizinische Klinik m.S. Gastroenterologie, Infektiologie & Rheumatologie, Campus Benjamin Franklin, Charité - Universitätsmedizin Berlin
"Macromolecule uptake across the mucosa in HIV infection"
PhD doctoral student, 2^nd cohort: Valerie Masete
PhD doctoral student, 1^st cohort: Carolin Grünhagen
MD doctoral student, 1^st cohort: Hannah Lutz

Impressum